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    (20R)-Ginsenoside Rh1
    Information
    CAS No. 80952-71-2 Price $188 / 20mg
    Catalog No.CFN92796Purity>=98%
    Molecular Weight638.9Type of CompoundTriterpenoids
    FormulaC36H62O9Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: (20R)-Ginsenoside Rh1 exhibits various pharmacological activities including vasorelaxation, antioxidation, anti-inflammation, and anticancer.
    In vitro:
    Japanese Journal of Pharmacognosy, 1985, 39:123-5.
    Pharmacological Study on Panax ginseng C.A. MEYER V. : Effects of Red Ginseng on the Experimental Disseminated Intravascular Coagulation (4). On Ginsenoside-Rg3, Rh1 and Rh2[Reference: WebLink]

    METHODS AND RESULTS:
    20S, 20R ginsenoside Rg3, 20S, 20R ginsenoside Rh1, and ginsenoside Rh2 isolated from red ginseng were investigated for their effect on blood platelet aggregation and thrombin-induced conversion of fibrinogen to fibrin in vitro.
    CONCLUSIONS:
    20S, 20R ginsenoside Rg3 inhibited collagen- and ADP-induced blood platelet aggregation. 20S ginsenoside Rg3, 20S, 20R ginsenoside Rh1 inhibited the thrombin-induced conversion of fibrinogen to fibrin.
    (20R)-Ginsenoside Rh1 Description
    Source: The roots of Panax ginseng C. A. Mey.
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.5652 mL 7.826 mL 15.6519 mL 31.3038 mL 39.1298 mL
    5 mM 0.313 mL 1.5652 mL 3.1304 mL 6.2608 mL 7.826 mL
    10 mM 0.1565 mL 0.7826 mL 1.5652 mL 3.1304 mL 3.913 mL
    50 mM 0.0313 mL 0.1565 mL 0.313 mL 0.6261 mL 0.7826 mL
    100 mM 0.0157 mL 0.0783 mL 0.1565 mL 0.313 mL 0.3913 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2013 Nov;38(22):3910-7.
    Chemical constituents from processed rhizomes of Panax notoginseng.[Pubmed: 24558875]

    METHODS AND RESULTS:
    To investigate the chemical constituents of the processed rhizomes of Panax notoginseng, their 70% ethanol extract was chromatographed on macroporous resin (SP825), silica gel, RP-C18 and semi-preparative HPLC to afford compounds 1-23. On the basis of physicochemical properties and spectral data analysis, their structures were identified to be 6'-O-Acetylginsenoside Rh1 (1), ginsenoside RK3 (2), ginsenoside Rh4 (3), 20S-ginsenoside Rg3 (4), ginsenoside Rk1 (5), 20R-ginsenoside Rg3 (6), ginsenoside Rg5 (7), ginsenoside F2 (8), 20S-ginsenoside Rh1 (9), (20R)-Ginsenoside Rh1(10), gypenoside X VII (11), notoginsenoside Fa, (12), ginsenoside Ra3 (13), ginsenoside Rg1 (14), ginsenoside Re (15), notoginsenoside R2 (16), ginsenoside Rg2 (17), notoginsenoside R1 (18), ginsenoside Rd (19), ginsenoside Rb1 (20), notoginsenoside D (21), notoginsenoside R4 (22) and ginsenoside Rb2 (23), respectively. Among them, compound 1 was isolated from P. notoginseng for the first time, and compounds 4, 6, 8 and 11 were isolated from the processed P. notoginseng for the first time.
    CONCLUSIONS:
    According to the fingerprint profiles of raw and processed P. notoginseng, the putative chemical conversion pathways of panoxatriol and panoxadiol compounds in the processing procedure was deduced, and the results revealed the main reactions to be dehydration and glycosyl hydrolysis.