• ChemFaces is a professional high-purity natural products manufacturer.
  • Product Intended Use
  • 1. Reference standards
  • 2. Pharmacological research
  • 3. Inhibitors
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • Science | Nature | Cell | View More
    Natural Products
    7-Methoxy-4-methylcoumarin
    7-Methoxy-4-methylcoumarin
    Information
    CAS No. 2555-28-4 Price $40 / 20mg
    Catalog No.CFN94405Purity>=98%
    Molecular Weight190.20Type of CompoundCoumarins
    FormulaC11H10O3Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $9.3 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Massachusetts General Hospital (USA)
  • Medical University of South Car... (USA)
  • National Research Council of Ca... (Canada)
  • Universit?t Basel (Switzerland)
  • Chiang Mai University (Thailand)
  • Universiti Sains Malaysia (Malaysia)
  • Complutense University of Madrid (Spain)
  • University of Malaya (Malaysia)
  • Leibniz-Institut für Pflanzenb... (Germany)
  • Vin?a Institute of Nuclear Scie... (Serbia)
  • Aveiro University (Portugal)
  • More...
  • Package
    Featured Products
    Ganoderic acid C6

    Catalog No: CFN92290
    CAS No: 105742-76-5
    Price: $368/10mg
    Scopolin

    Catalog No: CFN98887
    CAS No: 531-44-2
    Price: $168/20mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $368/5mg
    meso-Hannokinol

    Catalog No: CFN90864
    CAS No: N/A
    Price: $368/5mg
    Pomolic acid

    Catalog No: CFN99433
    CAS No: 13849-91-7
    Price: $413/5mg
    Pyrocurzerenone

    Catalog No: CFN96169
    CAS No: 20013-75-6
    Price: $388/20mg
    Ganoderic acid S

    Catalog No: CFN99066
    CAS No: 104759-35-5
    Price: $568/5mg
    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antibacterial Compound Library
  • Markers Compound Library
  • Coumarins Compound Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: 7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis.
    Targets: Antifection
    In vitro:
    Pak J Pharm Sci. 2015 May;28(3):819-23.
    Potential antibacterial activity of coumarin and coumarin-3-acetic acid derivatives[Reference: WebLink]
    Coumarin and coumarin-3-acetic acid derivatives were synthesized by reacting phenols with malic acid, ethyl acetoacetate and ethyl acetylsuccinate in appropriate reaction conditions.
    METHODS AND RESULTS:
    All synthesized compounds were subjected to test for their antimicrobial activities against variety of gram positive (Bacillus subtilis, Staphylococcus aureus) and gram negative bacterial stains (Shigella sonnei, Escherichia coli) by agar dilution method. Several of them exhibited appreciable good antibacterial activity against the different strains of gram positive and gram negative bacteria. These findings suggest a great potential of these compounds for screening and use as antibacterial agents for further studies with a battery of bacteria. Minimal inhibitory concentration values shows that experimental compounds were found less active in comparison to standard drug ciprofloxacin but showed parallel activity to moxifloxacin. From table 3, it can be concluded that all the compounds have displayed good activity against B. subtilis.
    CONCLUSIONS:
    Compounds were enough active against this bacterial strain especially 7-Methoxy coumarin (1), 7-Methyl coumarin (4), 6-methylcoumarin (5), 4,6-Dimethylcoumarin (7), 7-Methoxy-4-methylcoumarin (8) and 7-Methoxy-4-methylcoumarin-3- acetic acid (17). 6-Methylcoumarin (5), 7-methoxy-4- methylcoumarin (8) and 6-aminocoumarin-3-acetic acid (12) showed excellent activities against B. subtilis even better than standard drug amoxifloxacin.
    7-Methoxy-4-methylcoumarin Description
    Source: The herbs of Eupatorium pauciflorum.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Recent ChemFaces New Products and Compounds
    3-O-methylellagic acid 4'-O-alpha-...

    Catalog No: CFN95228
    CAS No: 51768-39-9
    Price: $413/5mg
    Leachianol F

    Catalog No: CFN95147
    CAS No: 164123-50-6
    Price: $318/5mg
    Arjungenin

    Catalog No: CFN95039
    CAS No: 58880-25-4
    Price: $318/10mg
    Hinokiflavone

    Catalog No: CFN92007
    CAS No: 19202-36-9
    Price: $318/10mg
    2''-O-Galloylquercitrin

    Catalog No: CFN95041
    CAS No: 80229-08-9
    Price: $418/5mg
    Gypenoside XVII

    Catalog No: CFN90193
    CAS No: 80321-69-3
    Price: $148/20mg
    Tuberosin

    Catalog No: CFN95107
    CAS No: 41347-45-9
    Price: $218/5mg
    New compound 3

    Catalog No: CFN95184
    CAS No: N/A
    Price: $368/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 5.2576 mL 26.2881 mL 52.5762 mL 105.1525 mL 131.4406 mL
    5 mM 1.0515 mL 5.2576 mL 10.5152 mL 21.0305 mL 26.2881 mL
    10 mM 0.5258 mL 2.6288 mL 5.2576 mL 10.5152 mL 13.1441 mL
    50 mM 0.1052 mL 0.5258 mL 1.0515 mL 2.103 mL 2.6288 mL
    100 mM 0.0526 mL 0.2629 mL 0.5258 mL 1.0515 mL 1.3144 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Journal of Chromatography A, 1985 , 328 :111-20.
    4-methyl-7-methoxycoumarin as a fluorescent label for high-performance liquid chromatographic analysis of dicarboxylic acids[Reference: WebLink]
    4-methyl-7-methoxycoumarin(7-Methoxy-4-methylcoumarin) as a fluorescent label for high-performance liquid chromatographic analysis of dicarboxylic acids