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  • 7-Methoxyneochamaejasmine A
    • 7-Methoxyneochamaejasmine A
    7-Methoxyneochamaejasmine A
    Information
    CAS No. 402828-38-0 Price $433 / 5mg
    Catalog No.CFN92156Purity>=98%
    Molecular Weight556.5Type of CompoundFlavonoids
    FormulaC31H24O10Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $963.9 / In-stock
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    • Biological Activity
    Description: 7-Methoxyneochamaejasmine A has a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings.
    In vitro:
    Plant Growth Regulation, 2015 , 77 (3) :335-342.
    Potential allelochemicals in root zone soils of Stellera chamaejasme L. and variations at different geographical growing sites[Reference: WebLink]
    Populations of Stellera chamaejasme L. have been increasing constantly in recent years in some areas of the grassland in north China but why this toxic weed has become highly competitive is not clear. In order to determine if any potential allelochemicals are released into the soil environment by S. chamaejasme, we investigated the chemical composition of a water-washed solution of the living roots with rhizosphere soil.
    METHODS AND RESULTS:
    This led to the isolation and identification of seven compounds: umbelliferone (1), daphnoretin (2), chamaechromone (3), 7-Methoxyneochamaejasmine A (4), mesoneochamaejasmin A (5), neochamaejasmin B (6), dihydrodaphnodorin B (7). All are secondary metabolites of S. chamaejasme. Bioassay showed that 1, 5 and 6 had a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings. These compounds were quantified by high performance liquid chromatography in 25 root zone soil samples of S. chamaejasme collected at altitudes between 165 and 4741 m from the northeast to the Tibetan Plateau of China. All samples contained at least one of the phytotoxic compounds. Their content did not correlate with the altitude of the growing site. However, the level of chamaechromone negatively correlated with the soil pH.
    CONCLUSIONS:
    Principle components analysis indicated that the flavonoids might come from the same source. These potential allelochemicals from root release into the soil might play an important role in the highly competitive nature and broad ecological adaptability of S. chamaejasme in the wild.
    7-Methoxyneochamaejasmine A Description
    Source: The roots of Stellera chamaejasme Linn.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

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    doi: 10.1016/j.molcel.2017.10.022.
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    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.7969 mL 8.9847 mL 17.9695 mL 35.9389 mL 44.9236 mL
    5 mM 0.3594 mL 1.7969 mL 3.5939 mL 7.1878 mL 8.9847 mL
    10 mM 0.1797 mL 0.8985 mL 1.7969 mL 3.5939 mL 4.4924 mL
    50 mM 0.0359 mL 0.1797 mL 0.3594 mL 0.7188 mL 0.8985 mL
    100 mM 0.018 mL 0.0898 mL 0.1797 mL 0.3594 mL 0.4492 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2002 Dec;4(4):259-63.
    Chemical constituents of Stellera chamaejasme L.[Pubmed: 12450253]
    A new biflavanone, 7-Methoxyneochamaejasmine A, and a new chromone derivative, isomohsenone, were isolated from the roots of Stellera chamaejasme L.
    METHODS AND RESULTS:
    The structures of two compounds were determined by means of ESI-MS, 1H NMR and 13C NMR, especially 2D NMR spectral analyses.
    CFN92151Neochamaejasmine A90411-13-5542.5C30H22O10
    CFN921567-Methoxyneochamaejasmine A402828-38-0556.5C31H24O10
    CFN92155Sikokianin A106293-99-6556.5C31H24O10
    CFN96514Sikokianin C159813-69-1556.52C31H24O10
    CFN92063Isochamaejasmenin B865852-48-8570.6C32H26O10
    CFN92062Chamaejasmenin A89595-71-1570.6C32H26O10
    CFN92061Chamaejasmenin C89595-70-0584.6C33H28O10
    CFN96558Ruixianglangdusu B447454-49-1584.57C33H28O10
    CFN92064Chamaejasmenin D865852-47-7570.6C32H26O10
    CFN92150Isochamaejasmine93859-63-3542.5C30H22O10
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