ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Mediators Inflamm. 2016, 2016:6189590Chemistry of Plant Materials....2016...Acta horticulturae2017, 1158:257-268Universite de Bordeaux...2017...J Biochem Mol Toxicol.2017, 31(9)Naunyn Schmiedebergs Arch Pharmac...2017...Front Aging Neurosci.2018, 10:269Int J Biol Macromol.2018, 112:1093-1103
ACS Nano.2018, 12(4):3385-3396Food Quality and Safety2018, 2:213-219Nat Prod Sci.2018, 24(2):109-114Journal of Physiology & Pathology...2018...Biochem Biophys Res Commun....2018...J Herbmed Pharmacol.2018, 7(4):280-286J Nat Med.2018, 72(3):734-744Planta Med.2018, 84(6-07):465-474
Microb Pathog.2019, 131:128-134Int J Mol Sci.2019, 20(16):E4015Food Engineering Progress...2019...Molecules.2019, 24(2):E343Anal Sci.2019, 35(12):1317-1325Oncol Rep.2019, 41(4):2453-2463Int J Pharmacol2020, 16:1-9
Our products had been exported to the following research institutions and universities, And still growing.
Institute of Bioorganic Chemist... (Poland)Lund University (Sweden)Instytut Nawozów Sztucznych w ... (Poland)Macau University of Science and... (China)
Chang Gung University (Taiwan)University of Queensland (Australia)Uniwersytet Medyczny w ?odzi (Poland)Siksha O Anusandhan University (India)
University of Bordeaux (France)Deutsches Krebsforschungszentrum (Germany)Regional Crop Research Institute (Korea)
Related Screening Libraries
||Actinidic acid is a triterpene phytoalexin from unripe kiwi fruit.
|Arch Pharm Res. 2008 May;31(5):666-70. |
|A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta.[Pubmed: 18481026]|
METHODS AND RESULTS:
A new coumaroyl triterpene, 3-O-trans-p-coumaroyl Actinidic acid (1), as well as five known triterpenes, ursolic acid (2), 23-hydroxyursolic acid (3), corosolic acid (4), asiatic acid (5) and betulinic acid (6) were isolated from an EtOAc-soluble extract of the roots of Actinidia arguta. The structure of compound 1 was elucidated from interpretation of the spectroscopic data, particularly by extensive 1D and 2D NMR studies. All the isolates (1-6) were evaluated in vitro for their inhibitory activities on pancreatic lipase (PL).
Of the isolates, the new compound 1 possessed the highest inhibitory activity on PL, with an IC(50) of 14.95 microM, followed by ursolic acid (2, IC(50) = 15.83 microM). The other four triterpenes (3-6) also showed significant PL inhibitory activity, with IC(50) values ranging from 20.42 to 76.45 microM.
Actinidic acid Description
||The leaves of Eucalyptus maideni
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Biosci Biotechnol Biochem. 2001 Feb;65(2):480-3. |
|Actinidic acid, a new triterpene phytoalexin from unripe kiwi fruit.[Pubmed: 11302196]|
METHODS AND RESULTS:
Seven phytoalexins (1-7), including a new compound, were isolated from the peel of unripe kiwi fruit (Actinidia deliciosa cv. Golden King) that had been wounded and inoculated with Colletotrichum musae. The new phytoalexin (1) was identified as 2alpha,3beta,23-trihydroxy-12,20(30)-ursadien-28-oic acid, and named Actinidic acid.
Phytoalexins 2-6 are known triterpenes but have not previously been described as phytoalexins. Phytoalexin 7 is the same triterpene as the phytoalexin of nectarine fruit.