ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules.2015, 20(10):19172-88Evid Based Complement Alternat Me...2015...Phytomedicine.2015, 22(4):498-503Mediators Inflamm.2016, 2016:7216912J Drug Target.2016, 24:1-28US20170000760 A12016, 42740Vojnosanit Pregl2016, 75(00):391-391Preprints2017, 2017120176
J of L. Chroma.&Related Tech...2017...Integr Med Res.2017, 6(4):395-403Sci Rep. 2018, 10590BMC Plant Biol.2018, 18(1):122Biol Pharm Bull.2018, 41(1):65-72Mol Cells.2018, 41(8):771-780Virulence.2018, 9(1):588-603J Cancer.2019, 10(23):5843-5851
New Journal of Chemistry...2019...J Asian Nat Prod Res.2019, 5:1-17Food Sci Nutr.2019, 8(1):246-256Sci Rep.2019, 9(1):6429Br J Pharmacol.2020, 10.1111LWT-Food Sci Technol2020, 109163Biochem Biophys Res Commun....2020...
Our products had been exported to the following research institutions and universities, And still growing.
Centralised Purchases Unit (CPU... (India)Universiti Kebangsaan Malaysia (Malaysia)St. Jude Children Research Hosp... (USA)Texas A&M University (USA)
Heinrich-Heine-University Düss... (Germany)Nicolaus Copernicus Uniwersity (Poland)Seoul National University (Korea)Universidad de Buenos Aires (Argentina)
Cancer Research Initatives Foun... (Malaysia)Northeast Normal University Cha... (China)Korea Food Research Institute(K... (Korea)
Related Screening Libraries
||Agatharesinol acetonide shows anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). |
|Chem Biodivers. 2005 Apr;2(4):497-505. |
|Norlignans from Sequoia sempervirens.[Pubmed: 17191998]|
METHODS AND RESULTS:
Six new norlignans, named sequosempervirins B-G (1-6), together with three known norlignans, agatharesinol (7), Agatharesinol acetonide (8), and sugiresinol (9), were isolated from the branches and leaves of Sequoia sempervirens. Their structures were determined mainly by high-resolution mass spectroscopy (HR-MS), and various 1D- and 2D-NMR methods, as well as, in the case of 1, by means of X-ray diffraction.
Compound 8 showed anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). The acetone extract of S. sempervirens was found to be antifungal towards Candida glabrata (IC50 = 15.98 microg/ml), and both the acetone and MeOH extracts inhibited the proteolytic activity of cathepsin B (IC50 = 4.58 and 5.49 microg/ml, resp.).
Agatharesinol acetonide Description
||The heartwoods of Sequoia sempervirens
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.