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    Isomangiferin
    Information
    CAS No. 24699-16-9 Price $268 / 10mg
    Catalog No.CFN90385Purity>=98%
    Molecular Weight422.34Type of CompoundXanthones
    FormulaC19H18O11Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    Isomangiferin Description
    Source: The herbs of Mangifera indica L.
    Biological Activity or Inhibitors: 1. Isomangiferin and mangiferin has antiviral effect, may due to their capability of inhibiting virus replication within cells.
    Solvent: Pyridine, DMSO.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.3678 mL 11.8388 mL 23.6776 mL 47.3552 mL 59.194 mL
    5 mM 0.4736 mL 2.3678 mL 4.7355 mL 9.471 mL 11.8388 mL
    10 mM 0.2368 mL 1.1839 mL 2.3678 mL 4.7355 mL 5.9194 mL
    50 mM 0.0474 mL 0.2368 mL 0.4736 mL 0.9471 mL 1.1839 mL
    100 mM 0.0237 mL 0.1184 mL 0.2368 mL 0.4736 mL 0.5919 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Isomangiferin References Information
    Citation [1]

    Chin Med J (Engl). 1990 Feb;103(2):160-5.

    Antiviral effect of mangiferin and isomangiferin on herpes simplex virus.[Pubmed: 2167819]
    Using tissue culture technique the present study for the first time indicated the antiviral effect of mangiferin and Isomangiferin against type I herpes simplex virus (HSV-I). 4 methods were used for evaluating drug effectiveness (i.e., in vitro drug-on-virus direct action, simultaneous addition of drug-virus-inoculum to cell bottle, virus inoculation preceding drug addition, and drug addition followed by virus inoculation), it was readily found by log determination of HSV-I inhibition that Isomangiferin somewhat exceeded such control drugs as acyclovir, idoxuridine, and cyclocytidine in log by 0.27-0.50, and that mangiferin was lower than Isomangiferin in log by 0.53. The average plaque reduction rates of mangiferin and Isomangiferin were 56.8% and 69.5% respectively. The antiviral effect of mangiferin and Isomangiferin was presumably due to their capability of inhibiting virus replication within cells.
    Citation [2]

    Zhongguo Yao Li Xue Bao. 1989 Jan;10(1):85-90.

    Antiviral effect of mangiferin and isomangiferin on herpes simplex virus[Pubmed: 2554669]
    Using tissue culture techniques the present study assured us of the merits of mangiferin and Isomangiferin in the antiviral action against HSV-1. Utilizing 4 main patterns for evaluating drug effectiveness (ie intratube drug-on-virus direct action, simultaneous addition of drug-virus-inoculum to cell bottle, virus inoculation preceding drug addition, and drug addition followed by virus inoculation), it was readily found by logarithm determination of HSV-I inhibition that Isomangiferin was superior to such control drugs as acyclovir, idoxuridine, and cyclocytidine in logarithm by 0.27-0.50, and that mangiferin was lower than Isomangiferin in logarithm by 0.53. The average plaque reduction rates of mangiferin and Isomangiferin were 69.5% and 56.8%, respectively. All in all, the antiviral effect of mangiferin and Isomangiferin was attributed presumably to their capability to inhibit virus replication within cells.