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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Inflammation.2015, 38(4):1502-16FEBS Lett.2015, 589(1):182-7Mediators Inflamm.2016, 2016:7216912Food and Bioprocess Technology...2017...J Chromatogr A.2017, 1518:46-58J Ethnopharmacol.2017, 198:91-97J Ethnopharmacol.2017, 206:327-336J of L. Chroma.&Related Tech...2017...
FEMS Microbiol Lett.2017, 364(11)Nutrients.2018, 10(7)Fitoterapia.2018, 124:92-102Exp Parasitol.2018, 194:67-78Phytomedicine.2018, 47:48-57Pathogens.2018, 7(3):E62J Nat Sc Biol Med2019, 10(2):149-156Front Pharmacol.2019, 10:1226
Int J Mol Sci.2019, 20(3):E651Molecules.2019, 24(22):E4022Plos One.2019, 15(2):e0220084Food Analytical Methods2020, 1-10Drug Des Devel Ther.2020, 14:61-71Appl Biochem Biotechnol....2020...Antioxidants (Basel).2020, 9(2):E99
Our products had been exported to the following research institutions and universities, And still growing.
Institute of Pathophysiology Me... (Austria)Leibniz-Institut für Pflanzenb... (Germany)FORTH-IMBB (Greece)Monash University (Australia)
Colorado State University (USA)Kyung Hee University (Korea)Universite de Lille1 (France)Siksha O Anusandhan University (India)
Vin?a Institute of Nuclear Scie... (Serbia)China Medical University (Taiwan)Fraunhofer-Institut für Moleku... (Germany)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Diterpenoids Compound Library
|| Andropanolide is a natural product from Andrographis paniculata (Burm. f.) Nees.|
|International Journal of Pharmacy & Pharmaceutical Sciences, 2014, 6(1):46–52. |
|MICROBIAL METABOLISM OF AN ANTI-HIV AND ANTI-MALARIAL NATURAL PRODUCT ANDROGRAPHOLIDE[Reference: WebLink]|
| In the present study, we first time studied the microbial metabolism of andrographolide (1) with Cunninghamella elegans (TSY 0865) and Cephalosporium aphidicola (IMI-68689). |
METHODS AND RESULTS:
Microbial cultures of the C. elegans and C. aphidicola were grown on Potato dextrose agar (PDA) at 25°C and stored at 4°C. Medium for C. aphidicola was prepared by mixing Glucose (50.0 g), KH2PO4 (1.0 g), MgSO4.7H2O (2.0 g), Glycin (2.0 g), KCl (1.0 g) and Gibberella trace element solution (2.0 mL) into distilled water (1 L) and maintained pH at 5.6. While C. elegans medium was prepared by adding Glucose (10.0 g), peptone (5.0 g), KH2PO4 .Two compounds were obtained as transformed products. Based on physical and spectroscopic data, these have been identified as Andropanolide (2) and 14-deoxy-11,12-didehydro andrographolide (3). Both compounds were previously obtained by the phytochemical investigation of A. paniculata and biotransformed product as well. (5.0 g), yeast extract (5.0 g), NaCl (5.0 g) and glycerol (10 mL) into distilled water (1 L) and maintained pH at 5.6.
It could be concluded that C. elegans and C. aphidicola were able to produce oxidative derivatives of 1 in a regio- and stereoselective manner. Present investigation has been conducted for the first time with C. elegans and C. aphidicola. Incubation of 1 for 9 days with fungal strains yielded isomerized and oxidative products 2 and 3. Structures of all metabolites were elucidated by using spectroscopic techniques.
||The herbs of Andrographis paniculata (Burm. f.) Nees
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Nat Prod. 2006 Mar;69(3):403-5. |
|Andropanolide and isoandrographolide, minor diterpenoids from Andrographis paniculata: structure and X-ray crystallographic analysis.[Pubmed: 16562845]|
METHODS AND RESULTS:
Phytochemical investigation of the leaves of Andrographis paniculata has led to the isolation of a new labdane type diterpenoid, Andropanolide (1), along with seven known diterpenoids including isoandrographolide (2), previously reported as a rearrangement product of andrographolide. The structures and stereochemistry of compounds Andropanolide and 2 were established by X-ray crystallographic analysis.