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    Pallidol
    Pallidol
    Information
    CAS No. 105037-88-5 Price $318 / 10mg
    Catalog No.CFN92341Purity>=98%
    Molecular Weight454.5Type of CompoundPhenols
    FormulaC28H22O6Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Pallidol is a potent and selective singlet oxygen quencher in aqueous systems, it may be used in singlet oxygen-mediated diseases as a pharmacological agent.
    Targets: ROS
    Pallidol Description
    Source: The herbs of Cissus pallida
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2002 mL 11.0011 mL 22.0022 mL 44.0044 mL 55.0055 mL
    5 mM 0.44 mL 2.2002 mL 4.4004 mL 8.8009 mL 11.0011 mL
    10 mM 0.22 mL 1.1001 mL 2.2002 mL 4.4004 mL 5.5006 mL
    50 mM 0.044 mL 0.22 mL 0.44 mL 0.8801 mL 1.1001 mL
    100 mM 0.022 mL 0.11 mL 0.22 mL 0.44 mL 0.5501 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Pallidol References Information
    Citation [1]

    Biochem Biophys Res Commun. 2009 Feb 6;379(2):283-7.

    Pallidol, a resveratrol dimer from red wine, is a selective singlet oxygen quencher.[Pubmed: 19101516]
    Pallidol is a naturally occurring resveratrol dimer from red wine with antioxidant and antifungal activities. In this report, with the use of the EPR spin-trapping technique, the scavenging and quenching effects of Pallidol on reactive oxygen species (ROS) were investigated. The results demonstrated that Pallidol showed strong quenching effects on singlet oxygen at very low concentrations, but it was ineffective to scavenge hydroxyl radicals or superoxide anions. Further kinetic study revealed that the reaction of Pallidol with singlet oxygen had an extremely high rate constant (k(a)=1.71x10(10)). Therefore, Pallidol is a potent and selective singlet oxygen quencher in aqueous systems. It may be used in singlet oxygen-mediated diseases as a pharmacological agent, which may contribute to the health beneficial effects of red wine.