ChemFaces is a professional high-purity natural products manufacturer.
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1. Reference standards
2. Pharmacological research
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More articles cited ChemFaces products.
Sci Rep. 2017 Dec 11;Biochem Pharmacol. 2017 Apr 15;Int J Mol Med.2015 Dec 28.Journal of Pharmaceutical Analysis2016 May 5; The Korea Society of Pharmacognosy.2014
Chem Pharm Bull (Tokyo).2017;65(9)Am J Chin Med.2016;44(6)J Cell Biochem.2018 Feb;Acta Agriculturae ScandinavicaJan. 18, 2016Anticancer Res.2014 Jul;34(7):3505-9.
Scientific Research.2015 Jan 6; 14-23Korean J. of Food Sci. and TechApril 2016Free Radic Biol Med.2017 Nov;Anal Bioanal Chem. 2016 Jun;408(15)
Our products had been exported to the following research institutions and universities, And still growing.
University of Bonn (Germany)Univerzita Karlova v Praze (Czech Republic)Universidad Veracuzana (Mexico)University of Parma (Italy)
Nicolaus Copernicus Uniwersity (Poland)Kamphaengphet Rajabhat University (Thailand)John Innes Centre (United Kingdom)Griffith University (Australia)
Calcutta University (India)Universidade Federal de Santa Ca... (Brazil)National Cancer Center Research ... (Japan)
||Arjunic acid is a strong antioxidant and a free radical scavenger.
Arjunic acid shows activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. |
||Antifection | COX|
|Am J Chin Med. 2008;36(1):197-207. |
|Arjunic acid, a strong free radical scavenger from Terminalia arjuna.[Pubmed: 18306462]|
|This study was designed to investigate the antioxidant and free radical scavenging capacities of Arjunic acid, an aglycone obtained from the fruit of medicine Terminalia Fruit. |
METHODS AND RESULTS:
Liver microsomes, mitochondria, and red blood cells (RBCs) were prepared from Wistar rats. The antioxidant capacity was determined by the inhibitory effect on lipid peroxidation, hydrogen peroxide induced RBCs hemolysis, and RBCs autoxidative hemolysis. The free radical scavenging activity was tested by DPPH method and 2',7'-dichlorodihydrofluoresc in diacetate (DCFH(2)-DA) assay. Ascorbic acid was chosen as the positive controls. Results showed that Arjunic acid was a strong antioxidant and a free radical scavenger, more potent than ascorbic acid, in microsomes lipid peroxidation, DPPH, hydrogen peroxide induced RBCs hemolysis, and (DCFH(2)-DA) assay (p < 0.05). However, no significant difference was observed in the RBCs autoxidative hemolysis assay (p > 0.05).
|Planta Med. 2008 Mar;74(4):411-3. |
|Isolation and biological activities of termilignan B and arjunic acid from Terminalia sericea roots.[Pubmed: 18484533]|
|Bioassay-guided fractionation of ethyl acetate root extracts of Terminalia sericea yielded a new compound, termilignan B, and the known Arjunic acid. |
METHODS AND RESULTS:
Both compounds showed activity against Gram-positive and Gram-negative bacteria with MIC values ranging between 1.9 and 15.6 microg/mL. The lowest MIC value (1.9 microg/mL) was observed with termilignan B against Bacillus subtilis. Neither of the compounds showed significant activity against Mycobacterium aurum A+. In the cyclooxygenase assays, the compounds showed weak inhibitory activity with IC (50) values of 78 microM (COX-1) and 156 microM (COX-2) (termilignan B) and 36 microM (COX-1) and 253 microM (COX-2) (Arjunic acid). No potential mutagenic effects were observed with the two compounds in the Salmonella microsome assay (TA 98).
Arjunic acid Description
||The stem barks of Terminalia arjuna
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.