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    Cistanoside A
    CAS No. 93236-42-1 Price $218 / 10mg
    Catalog No.CFN90526Purity>=98%
    Molecular Weight800.75Type of CompoundPhenylpropanoids
    FormulaC36H48O20Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    Biological Activity
    Description: 1. Cistanoside A possesses protective activities on CCl4 induced hepatotoxicity in mice, which is involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria.
    Targets: SOD
    Cistanoside A Description
    Source: The herbs of Cistanche deserticola Ma
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
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    J Cell Biochem. 2018 Feb;119(2):2231-2239.
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    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.2488 mL 6.2441 mL 12.4883 mL 24.9766 mL 31.2207 mL
    5 mM 0.2498 mL 1.2488 mL 2.4977 mL 4.9953 mL 6.2441 mL
    10 mM 0.1249 mL 0.6244 mL 1.2488 mL 2.4977 mL 3.1221 mL
    50 mM 0.025 mL 0.1249 mL 0.2498 mL 0.4995 mL 0.6244 mL
    100 mM 0.0125 mL 0.0624 mL 0.1249 mL 0.2498 mL 0.3122 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Cistanoside A References Information
    Citation [1]

    Latin American Journal of Pharmacy; 2012 vol. 31, no. 3

    Protective Activities of Cistanoside A on CCl4 Induced Hepatotoxicity in Mice[Reference: WebLink]
    To evaluate the protective efficacy of Cistanoside A (C.A), a phenylethanol glycoside isolated from Cistanche deserticola, on CCl4 induced hepatotoxicity in mice, 50 animals were divided into five different protocols, and hepatic functional index were detected by diagnostic kits.To confirm the effect of Cistanoside A on free radical, tests on the free radical scavenging activities were also carried out in vitro. We found treatment with Cistanoside A (10, 20 mg/kg o.p. for 7 days) could significantly ameliorated the levels of hepatic function indices (AST, ALT, ALP and LDH) (P < 0.05). The biochemical results were also confirmed by histopathological examination. Cistanoside A treatment decreased the ballooning degeneration, moderated the hepatocytes apoptosis, and alleviated centrilobular and bridging necrosis which were observed in the CCl4 control group. Following experiments revealed that Cistanoside A could increase the activities of mitochondrial antioxidant enzymes (GST, SOD, and CAT) and respiratory marker enzymes (MDH, SDH, NADH dehydrogenase, and cytochrome c oxidases) (P < 0.05). In vitro, Cistanoside A exhibited strong scavenging activities for DPPH radical and superoxide anion radical. Our results revealed that Cistanoside A possess protective activities on CCl4 induced hepatotoxicity in mice, which was involved with increasing free radicals clearing activities, alleviating lipid-overoxidation damage, and improving respiratory chain function in mitochondria.