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    Deoxylapachol
    Information
    CAS No. 3568-90-9 Price
    Catalog No.CFN98473Purity>=98%
    Molecular Weight226.3 Type of CompoundQuinones
    FormulaC15H14O2Physical DescriptionYellow oil
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)
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    Deoxylapachol Description
    Source: The leaves of Catalpa ovata G. Don.
    Biological Activity or Inhibitors: 1. Deoxylapachol from T. grandis extract can induce fungal cell wall stress.
    2. Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.4189 mL 22.0946 mL 44.1891 mL 88.3783 mL 110.4728 mL
    5 mM 0.8838 mL 4.4189 mL 8.8378 mL 17.6757 mL 22.0946 mL
    10 mM 0.4419 mL 2.2095 mL 4.4189 mL 8.8378 mL 11.0473 mL
    50 mM 0.0884 mL 0.4419 mL 0.8838 mL 1.7676 mL 2.2095 mL
    100 mM 0.0442 mL 0.2209 mL 0.4419 mL 0.8838 mL 1.1047 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Deoxylapachol References Information
    Citation [1]

    Planta Med. 2006 Aug;72(10):943-4.

    Activity of quinones from teak (Tectona grandis) on fungal cell wall stress.[Pubmed: 16972200]
    Teak ( Tectona grandis L.f., Verbenaceae) sawdust extract inhibited the growth of Aspergillus niger. Centrifugal partition chromatography was used to isolate the active compounds. By (1)H-NMR the active compounds were identified as Deoxylapachol and tectoquinone. Two A. niger transgenic strains which show induction of 1,3 -alpha-D-glucan synthase were used as a cell wall damage model. The result showed that Deoxylapachol from T. grandis extract induced fungal cell wall stress.
    Citation [2]

    J. Wood Chem.Technol.,2008, 28(4):247- 60.

    Identification of Anti-Wood Rot Compounds in Teak (Tectona grandis L.f.) Sawdust Extract.[Reference: WebLink]
    The tropical hardwood sawdust of Tectona grandis L.f. from the wood processing industry was extracted and tested for anti-wood rot activity. Tectona grandis extract inhibited the brown rot fungi Gloeophyllum sepiarium, Gloeophyllum trabeum, Piptoporus betulinus and Serpula lacrymans, and the white rot fungi Bjerkandera adusta, Merulius tremellosus, and Phlebia brevispora. Centrifugal partition chromatography was used to separate these compounds using n-hexane-MeOH-H2O (50:47.5:2.5) as a solvent system. The compounds Deoxylapachol, tectoquinone, 2-hydroxymethylanthraquinone, 3′-OH-deoxyisolapachol (2-[(1E)-3-hydroxy-3-methylbut-1-enyl]naphthoquinone), hemitectol (2,2-dimethyl-2H-benzo[h]chromen-6-ol), and tectol were isolated from Tectona grandis sawdust CHCl3-MeOH (1:1) extract. Deoxylapachol inhibited the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevispora CBS 509.92. Hemitectol together with tectol showed a high percentage of cellulase inhibition followed by 3′-OH-deoxyisolapachol and Deoxylapachol.