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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $113.2 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Asian Journal of Chemistry...2014...China Pharmacy2015, 26(27)The Journal of Internal Korean Me...2015...Ind Crops Prod.2015, 67:185-191Chemistr of plant2016, 2016021195Biochem Systematics and Ecology...2017...Semyung University2017, 149407Preprints2017, 2017120176
Oncotarget.2017, 9(3):4161-4172Industrial Crops and Products...2017...Int J Biol Macromol.2018, 112:1093-1103J Cell Biochem.2018, 119(2):2231-2239ACS Nano.2018, 12(4):3385-3396J of the Society of Cosmetic Scie...2018...Toxicol In Vitro.2018, 52:94-105Sci Rep.2018, 8(1):12970
Molecules.2019, 24(4):E709Phytother Res.2019, 33(5):1490-1500Int J Mol Med.2019, 43(6):2516-2522Phytomedicine.2019, 65:153089TCI CO.2019, US20190151281A1Plant Cell Tiss Org2020, 1-16Antioxidants (Basel).2020, 9(2):E99
Our products had been exported to the following research institutions and universities, And still growing.
Universidade Federal de Santa C... (Brazil)Instituto de Investigaciones Ag... (Chile)Centralised Purchases Unit (CPU... (India)Sanford Burnham Medical Researc... (USA)
University of Hertfordshire (United Kingdom)Lodz University of Technology (Poland)Mahatma Gandhi University (India)Seoul National University of Sc... (Korea)
Shanghai Institute of Biochemis... (China)Warszawski Uniwersytet Medyczny (Poland)Lund University (Sweden)
Related Screening Libraries
||Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity. |
||Immunology & Inflammation related|
|Phytother Res. 2000 Sep;14(6):463-5. |
|Antiinflammatory activity and chemical composition of extracts of Verbena officinalis.[Pubmed: 10960904]|
METHODS AND RESULTS:
In an attempt to locate the biologically active fraction(s) of the plant Verbena officinalis Linn. (Verbenaceae), a preliminary screening of successive petroleum ether, chloroform and methanol extracts of aerial parts for antiinflammatory activity using carrageenan paw oedema model was carried out. All three extracts were found to exhibit antiinflammatory activity with the chloroform extract being the most active. Chemical investigations of petroleum ether and chloroform extracts led to the isolation of beta-sitosterol, ursolic acid, oleanolic acid, 3-epiursolic acid, 3-epioleanolic acid, and minor triterpenoids of derivatives of ursolic acid and oleanolic acids.
Chromatographic purification of the methanol extract yielded two iridoid glucosides, verbenalin and Hastatoside, a phenylpropanoid glycoside, verbascoside and beta-sitosterol-D-glucoside.
|Sleep & Biological Rhythms, 2009, 7(3):211–217. |
|Hastatoside and verbenalin are sleep‐promoting components in Verbena officinalis[Reference: WebLink]|
|Herbal tea made from Verbena officinalis (V. officinalis) has traditionally been used for the treatment of insomnia and other nervous conditions. |
METHODS AND RESULTS:
In this study, we examined the sleep-promoting activity of Hastatoside, verbenalin, and verbascoside, which are the major iridoids (Hastatoside and verbenalin) and polyphenol (verbascoside) components responsible for the pharmacological activity of V. officinalis, by electroencephalographic analysis of rats after oral administration of the compounds. Hastatoside (0.64 mmol/kg of body weight) and verbenalin (1.28 mmol/kg of body weight) increased the total time of non-rapid eye movement sleep during a 9-h period from 23.00 to 08.00 hours by 81% and 42%, respectively, with a lag time of about 3–5 h after the administration at 20.00 hours (lights-off time). Both compounds also increased the delta activity during non-rapid eye movement sleep. However, verbascoside had no effect on the amount of sleep.
Therefore, Hastatoside and verbenalin are major sleep-promoting components of V. officinalis.
||The herbs of Verbena officinalis L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.