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More articles cited ChemFaces products.
Phytomedicine15 Dec. 2015,1262–1268LWT - Food Science and Technology2017 Jan.Nat Plants. 2016 Dec 22Int J Mol Sci.2015 Jan 6;16(1):1232-51.Universite de Bordeaux15 Dec 2017;
Cell11 Jan. 2018;Phytochemistry2017 Jun;Invest New Drugs. 2017 Apr;Fitoterapia. 2018 Jan;Acta Physiologiae PlantarumJanuary 2016, 38:7
Scientific Reports2015 August 26 J Pharm Biomed Anal.2018 Mar 20;Planta Med 2016 Apr 28.J Bone Miner Res. 2017 Jul 26.
Our products had been exported to the following research institutions and universities, And still growing.
Florida International University (USA)Mendel University in Brno (Czech Republic)University of Bonn (Germany)Uniwersytet Jagielloński w Krak... (Poland)
University of Maryland School of... (USA)Warszawski Uniwersytet Medyczny (Poland)Cancer Research Initatives Found... (Malaysia)University of Fribourg (Switzerland)
University of Dicle (Turkey)Helmholtz Zentrum München (Germany)Aveiro University (Portugal)
||Hastatoside and verbenalin are major sleep-promoting components of V. officinalis. Hastatoside has anti-inflammatory activity. |
||Immunology & Inflammation related|
|Phytother Res. 2000 Sep;14(6):463-5. |
|Antiinflammatory activity and chemical composition of extracts of Verbena officinalis.[Pubmed: 10960904]|
METHODS AND RESULTS:
In an attempt to locate the biologically active fraction(s) of the plant Verbena officinalis Linn. (Verbenaceae), a preliminary screening of successive petroleum ether, chloroform and methanol extracts of aerial parts for antiinflammatory activity using carrageenan paw oedema model was carried out. All three extracts were found to exhibit antiinflammatory activity with the chloroform extract being the most active. Chemical investigations of petroleum ether and chloroform extracts led to the isolation of beta-sitosterol, ursolic acid, oleanolic acid, 3-epiursolic acid, 3-epioleanolic acid, and minor triterpenoids of derivatives of ursolic acid and oleanolic acids.
Chromatographic purification of the methanol extract yielded two iridoid glucosides, verbenalin and Hastatoside, a phenylpropanoid glycoside, verbascoside and beta-sitosterol-D-glucoside.
|Sleep & Biological Rhythms, 2009, 7(3):211–217. |
|Hastatoside and verbenalin are sleep‐promoting components in Verbena officinalis[Reference: WebLink]|
|Herbal tea made from Verbena officinalis (V. officinalis) has traditionally been used for the treatment of insomnia and other nervous conditions. |
METHODS AND RESULTS:
In this study, we examined the sleep-promoting activity of Hastatoside, verbenalin, and verbascoside, which are the major iridoids (Hastatoside and verbenalin) and polyphenol (verbascoside) components responsible for the pharmacological activity of V. officinalis, by electroencephalographic analysis of rats after oral administration of the compounds. Hastatoside (0.64 mmol/kg of body weight) and verbenalin (1.28 mmol/kg of body weight) increased the total time of non-rapid eye movement sleep during a 9-h period from 23.00 to 08.00 hours by 81% and 42%, respectively, with a lag time of about 3–5 h after the administration at 20.00 hours (lights-off time). Both compounds also increased the delta activity during non-rapid eye movement sleep. However, verbascoside had no effect on the amount of sleep.
Therefore, Hastatoside and verbenalin are major sleep-promoting components of V. officinalis.
||The herbs of Verbena officinalis L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
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* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.