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    Melamine
    Melamine
    Information
    CAS No. 108-78-1 Price $30 / 20mg
    Catalog No.CFN96945Purity>=98%
    Molecular Weight126.12Type of CompoundAlkaloids
    FormulaC3H6N6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Our products had been exported to the following research institutions and universities, And still growing.
  • Julius Kühn-Institut (Germany)
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  • Package
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    Biological Activity
    Description: 1. Melamine has nephrotoxic, the combination of melamine and cyanuric acid can cause acute renal failure in cats.
    2. The intumescent system additives( filled with ammonium polyphosphate, pentaerythritol and melamine) is an effective flame retardant on improving combustion properties for polypropylene.
    Melamine Description
    Source: Forms synthetic resins with formaldehyde.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 7.929 mL 39.6448 mL 79.2896 mL 158.5791 mL 198.2239 mL
    5 mM 1.5858 mL 7.929 mL 15.8579 mL 31.7158 mL 39.6448 mL
    10 mM 0.7929 mL 3.9645 mL 7.929 mL 15.8579 mL 19.8224 mL
    50 mM 0.1586 mL 0.7929 mL 1.5858 mL 3.1716 mL 3.9645 mL
    100 mM 0.0793 mL 0.3964 mL 0.7929 mL 1.5858 mL 1.9822 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Melamine References Information
    Citation [1]

    J Vet Diagn Invest. 2007 Nov;19(6):616-24.

    Assessment of melamine and cyanuric acid toxicity in cats.[Pubmed: 17998549 ]
    The major pet food recall associated with acute renal failure in dogs and cats focused initially on Melamine as the suspect toxicant. In the course of the investigation, cyanuric acid was identified in addition to Melamine in the offending food. The purpose of this study was to characterize the toxicity potential of Melamine, cyanuric acid, and a combination of Melamine and cyanuric acid in cats. In this pilot study, Melamine was added to the diet of 2 cats at 0.5% and 1%, respectively. Cyanuric acid was added to the diet of 1 cat at increasing doses of 0.2%, 0.5%, and 1% over the course of 10 days. Melamine and cyanuric acid were administered together at 0%, 0.2%, 0.5%, and 1% to 1 cat per dose group. No effect on renal function was observed in cats fed with Melamine or cyanuric acid alone. Cats dosed with a combination were euthanized at 48 hours after dosing because of acute renal failure. Urine and touch impressions of kidneys from all cats dosed with the combination revealed the presence of fan-shaped, birefringent crystals. Histopathologic findings were limited to the kidneys and included crystals primarily within tubules of the distal nephron, severe renal interstitial edema, and hemorrhage at the corticomedullary junction. The kidneys contained estimated Melamine concentrations of 496 to 734 mg/kg wet weight and estimated cyanuric acid concentrations of 487 to 690 mg/kg wet weight. The results demonstrate that the combination of Melamine and cyanuric acid is responsible for acute renal failure in cats.
    Citation [2]

    Polymer, 1998, 39(10):1951-1955.

    Dynamic. Flame retardancy of polypropylene filled with ammonium polyphosphate, pentaerythritol and melamine additives[Reference: WebLink]
    The dynamic flammability properties of an intumescent fire retardant polypropylene filled with ammonium polyphosphate, pentaerythritol and Melamine was discussed in this study. To evaluate the flammability properties of the materials, limit oxygen index, smoke emission, tensile strength, and our exploitation ‘dynamic flammability evaluation system’ tests were assessed in experiments. The results showed that the intumescent fire retardant filled polypropylene has superior flammability properties and keeps its mechanical strength. It also can be seen that CO concentration and smoke emission decrease while burning. It is concluded that this intumescent system additives is an effective flame retardant on improving combustion properties for polypropylene.