ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
More articles cited ChemFaces products.
Phytochem Anal.2013 Sep-Oct.Br J Pharmacol.2016 Jan;173(2):396-410.Arch Toxicol. 2017 Mar 20. Aquaculture1 Dec. 2017Am J Chin Med.2016;44(6)
Front Pharmacol. 2017 Apr 25;Naunyn Schmiedebergs Arch Pharmacol. 2017 Jul 21. Universite de Bordeaux15 Dec 2017;Cell Physiol Biochem. 2017;44(4);British Jou. Med. & Med. Research2014 Jan 1
Anal Bioanal Chem.2018 Feb;Molecules. 2017 Feb 21;J Ethnopharmacol. 2017 Jan 20;Hindawi Publishing Corporation2015 July 30
Our products had been exported to the following research institutions and universities, And still growing.
Universit?t Basel (Switzerland)University of Auckland (New Zealand)Biotech R&D Institute (USA)Universite Libre de Bruxelles (Belgium)
Sanford Burnham Medical Research... (USA)Instytut Nawozów Sztucznych w P... (Poland)St. Jude Children Research Hospi... (USA)University of Leipzig (Germany)
Imperial College London (United Kingdom)Universidad de Buenos Aires (Argentina)Texas A&M University (USA)
Methyl L-pyroglutamate Description
||The roots of Brachystemmacalycinum D.Don.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Bioorg Med Chem Lett. 2015 May 1;25(9):1965-70. |
|Synthesis of [(11)C]GSK1482160 as a new PET agent for targeting P2X(7) receptor.[Pubmed: 25819093 ]|
METHODS AND RESULTS:
The authentic standards GSK1482160 and its isomer, as well as the radiolabeling precursors desmethyl-GSK1482160 and Boc-protected desmethyl-GSK1482160 were synthesized from L-pyroglutamic acid, Methyl L-pyroglutamate and 2-chloro-3-(trifluoromethyl)benzylamine with overall chemical yield 27-28% in 3 steps, 58% in 4 steps, 76% in 1 step and 33% in 2 steps, respectively. [(11)C]GSK1482160 was prepared from either desmethyl-GSK1482160 or Boc-protected desmethyl-GSK1482160 with [(11)C]CH3OTf through N-[(11)C]methylation and isolated by HPLC combined with SPE in 40-50% and 30-40% radiochemical yield, respectively, based on [(11)C]CO2 and decay corrected to end of bombardment (EOB).
The radiochemical purity was >99%, and the specific activity at EOB was 370-1110 GBq/μmol with a total synthesis time of ～40-min from EOB.