ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules. 2013, 18(7):7376-88British Jou. Med.&Med. Research...2014...J Breast Cancer.2015, 18(2):112-118Analytical sci. & Tech2016, 186-193Mediators Inflamm.2016, 2016:7216912Phytomedicine.2016, 23(4):331-9Nutrients.2017, 10(1)Preprints2017, 2017120176
J Chromatogr B Analyt Technol Bio...2018...Phytochemistry2018, 15:83-92Molecules.2018, 23(7):E1659Nat Prod Sci.2018, 24(2):109-114J Sep Sci.2018, 41(11):2488-2497Biofactors.2018, 44(2):168-179Drug Invention Today...2019...Nutr Metab (Lond).2019, 16:31
Molecules.2019, 24(19):E3417Molecules.2019, 24(22):E4022Food Sci Nutr.2019, 8(1):246-256Sci Rep.2019, 9:19059Oxid Med Cell Longev2019, 9056845:13United States Patent Application...2020...Biochem Biophys Res Commun....2020...
Our products had been exported to the following research institutions and universities, And still growing.
Michigan State University (USA)Chiang Mai University (Thailand)University of Lodz (Poland)Nicolaus Copernicus Uniwersity (Poland)
Georgia Institute of Technology (USA)Universite Libre de Bruxelles (Belgium)Medical University of Gdansk (Poland)Tokyo Woman's Christian University (Japan)
Rio de Janeiro State University (Brazil)National Chung Hsing University (Taiwan)Instituto Politécnico de Bragan?a (Portugal)
Related Screening Libraries
|| Momordicoside K has antidiabetic activity.|
|Nat Prod Commun. 2014 Jun;9(6):765-9. |
|Novel cucurbitane triterpenoids and anti-cholinesterase activities of constituents from Momordica charantia L.[Pubmed: 25115074]|
METHODS AND RESULTS:
The C-19 epimers of 5beta,19-epoxycucurbita-6,23(E),25(26)-triene-3f,19-diol (1) and 5/,19-epoxy-25-methoxycucurbita-6,23-diene-3beta,19-diol (2) along with (19R,23E)-5beta,19-epoxy-19-methoxycucurbita-6,23,25-trien-3beta-ol (3), (23E)-5beta,19-epoxycucurbita-6,23-diene-3beta,25-diol (4), ligballinol (5), charantin (6) and Momordicoside K(7) were isolated from the green fruits of Momordica charantia. The (S)-epimers of 1 and 2 are the first reports in nature.
The acetyl- and butyryl-cholinesterase inhibitory activities of the isolated compounds were evaluated, and 5 showed the highest activity of these compounds against butyrylcholinesterase (IC50 = 32.20 microM) with a reversible and non-competitive inhibition mode.
Momordicoside K Description
||The herbs of Mormodica charantia L.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.