ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Myriceric acid C
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More articles cited ChemFaces products.
Oncology LettersJan. 25, 2018;Badan Litbangkes Kemenkes RINo 4 (2016)Preprints.25 Dec. 2017;Korean J. of Horticultural Sci. & Tech. No.2, 2017.2Journal of Analytical ChemistryAug. 2017;
ScientificWorldJournal. 2014 Feb 9.Evid Based Complement Alternat Med. 2017:6360836.Sci Rep. 2017 Aug 15;J. Acta Agr. Scandinavica17 Apr 2017LWT - Food Science and Technology2017 Jan.
Plant Cell Physiol.2018 Jan 1;Korean J. of Food Sci. and TechApril 2016J Chromatogr B Analyt Tec. Bio. Life Sci. 2017 Oct 1;Horticultural Science2016
Our products had been exported to the following research institutions and universities, And still growing.
Copenhagen University (Denmark)Universidade Católica Portuguesa (Portugal)FORTH-IMBB (Greece)Mahidol University (Thailand)
University of Helsinki (Finland)Fraunhofer-Institut für Molekul... (Germany)University of Wuerzburg (Germany)University of Hull (United Kingdom)
University of Eastern Finland (Finland)Shanghai Institute of Biochemist... (China)Regional Crop Research Institute (Korea)
|| Myriceric acid C has cytotoxic activity against human lung carcinoma and breast carcinoma.|
|Chem Pharm Bull (Tokyo). 2005 Jan;53(1):56-9. |
|Constituents from the stems of Hibiscus taiwanensis.[Pubmed: 15635230]|
METHODS AND RESULTS:
Five new compounds, hibicuslide A (1), hibicuslide B (2), hibicuslide C (3), hibicutaiwanin (4), hibicusin (5), and fifty-one known compounds have been isolated from the stems of Hibiscus taiwanensis. The structures of these compounds were determined by spectroscopic and chemical transformation methods.
Among them, mansonone H (19) and uncarinic acid A (30) inhibited HIV replication in H9 lymphocyte cells.
The 9,9'-O-feruloyl-(-)-secoisolaricinresinol (12), Myriceric acid C (29), and uncarinic acid A (30) showed cytotoxic activity against human lung carcinoma and breast carcinoma.
Myriceric acid C Description
||The herbs of Myrica cerifera
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.PMID: 29328914
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.PMID: 29149595
Scientific Reports 2017 Dec 11;7(1):17332.doi: 10.1038/s41598-017-17427-6.PMID: 29230013
Molecules. 2017 Oct 27;22(11). pii: E1829.doi: 10.3390/molecules22111829.PMID: 29077044
J Cell Biochem. 2018 Feb;119(2):2231-2239.doi: 10.1002/jcb.26385. PMID: 28857247
Phytomedicine. 2018 Feb 1;40:37-47. doi:10.1016/j.phymed.2017.12.030PMID: 29496173
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Chem Pharm Bull (Tokyo). 1996 Feb;44(2):343-51. |
|Endothelin receptor antagonist triterpenoid, myriceric acid A, isolated from Myrica cerifera, and structure activity relationships of its derivatives.[Pubmed: 8998841]|
METHODS AND RESULTS:
As the first non-peptide endothelin receptor antagonist from a higher plant, a new triterpenoid, myriceric acid A (50-235) (1) was isolated from the bayberry, Myrica cerifera. Myriceric acid A (1) inhibited not only an endothelin-1-induced increase in cytosolic free Ca2+ concentration (IC50 = 11 +/- 2 nM) but [125I]endothelin-1 binding in rat aortic smooth muscle cells (Ki = 66 +/- 15 nM).
Two new related triterpenoids, Myriceric acid C (6), and myriceric acid D (8), were also isolated. Furthermore, the chemical modification of these natural products led to the synthesis of sulfated derivatives (13, 14, 15) which showed 1.5 to 20 times higher affinity for endothelin receptors. The structure activity relationships of myriceric acids and their derivatives are discussed.