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    Asperglaucide
    Information
    CAS No. 56121-42-7 Price $238 / 5mg
    Catalog No.CFN98937Purity>=98%
    Molecular Weight444.5 Type of CompoundAlkaloids
    FormulaC27H28N2O4Physical DescriptionPowder
    Download Manual    COA    MSDSSimilar structuralComparison (Web)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $238 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Nematicidal Compound Library
  • Alkaloids Compound Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: Asperglaucide shows some nematocidal property against M. incognita.
    Targets: Antifection
    In vitro:
    Chemistry & Biodiversity,2006,3(2):224–230.
    New Antioxidant Phenolic Glycosides from Walsura yunnanensis[Reference: WebLink]
    Four new polyphenolic glycosides (1–4) were isolated from the BuOH extract of the bark of Walsura yunnanenis C. Y. Wu.
    METHODS AND RESULTS:
    These compounds comprise two lignans, i.e., the 9-O-α-l-arabinopyranosides 1 and 2 of (−)-isolariciresinol and of (+)-5-methoxyisolariciresinol, respectively, and the two phenolic glycosides 3,4,5-trimethoxyphenyl 2-O-(α-l-fucopyranosyl)-β-d-glucopyranoside (3) and 3,5-dihydroxyphenyl 6-O-(4-hydroxy-3,5-dimethoxybenzoyl)-β-d-glucopyranoside (walsuraside; 4). In addition, three known compounds, 3,4,5-trimethoxyphenyl β-d-glucopyranoside, Asperglaucide, and butyl α-d-fructofuranoside were identified. Their structures were elucidated spectroscopically and by chemical transformation (hydrolysis).
    CONCLUSIONS:
    The new compounds 1, 2, and 4 displayed significant antioxidant activities, with IC50 values in the range of ca. 42 to 49 μg/ml.
    Quím Nova, 2003, 26(3):335-9
    Isolamento e avaliação da atividade nematicida de constituintes químicos de Mucuna cinerea contra Meloidogyne incognita e Heterodera glycines[Reference: WebLink]

    METHODS AND RESULTS:
    Phytochemical investigation of the aerial parts and roots of mucuna cinerea led to the isolation of a mixture of fatty acids, triacylglicerols, b-sitosterol, stigmasterol, stigmasterol glucoside, daucosterol, Asperglaucide (4) and the isoflavonoids prunetin (1), genistein (2), medicarpin (3), daidzein (5), 7-o-a-glycopiranosyl daidzein (6). an in vitro bioassay was carried out with compounds 1-4, at the concentration of 50 and 5 mg ml-1 against the phytonematodes m. incognita and h. glycines.
    CONCLUSIONS:
    although the four compounds showed some nematocidal property, the most active was (1), causing 70% mortality of m. incognita at the concentration of 50 mg ml-1.
    Asperglaucide Description
    Source: The herbs of Walsura yunnanensis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
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    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2497 mL 11.2486 mL 22.4972 mL 44.9944 mL 56.243 mL
    5 mM 0.4499 mL 2.2497 mL 4.4994 mL 8.9989 mL 11.2486 mL
    10 mM 0.225 mL 1.1249 mL 2.2497 mL 4.4994 mL 5.6243 mL
    50 mM 0.045 mL 0.225 mL 0.4499 mL 0.8999 mL 1.1249 mL
    100 mM 0.0225 mL 0.1125 mL 0.225 mL 0.4499 mL 0.5624 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2007 Sep-Dec;9(6-8):763-70.
    Dicliptercerebroside, a novel cerebroside from Dicliptera chinensis.[Pubmed: 17994394]

    METHODS AND RESULTS:
    A novel cerebroside named dicliptercerebroside (1) was isolated from the whole herb of Dicliptera chinensis, together with two known compounds Asperglaucide (2) and amidoalcohol (3) for the first time from the title plant. Their structures were elucidated using spectroscopic methods.
    CONCLUSIONS:
    The structure of dicliptercerebroside was determined as 1-O-beta-D-glucopyranosyl-2N-[(2'R)-2'-hydroxy-(9Z)-palmitoleoyl]-2S,3S,4R-C(20)-phytosphingosine.