ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
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Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / Inquiry||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Int J Mol Sci.2015, 16(8):18396-411Clin Exp Pharmacol Physiol....2015...Korean Herb. Med. Inf. 2016, 4(1):35-42Evid Based Complement Alternat Me...2017...Food Chem.2017, 221:1135-1144J Food Compos Anal2017, 62:197-204Plant J.2017, 90(3):535-546Fitoterapia.2018, 124:92-102
Mol Pharm.2018, 15(8):3285-3296BMC Pharmacol Toxicol.2018, 19(1):5Bioorg Med Chem.2018, 26(14):4201-4208Phytother Res.2018, 32(5):923-932J Sep Sci.2018, 41(11):2488-2497The Japan Society for Analytical ...2018...Biorxiv2019, 10.1101Nutrients.2019, 12(1)
BMC Microbiol.2019, 19(1):78Molecules.2019, 24(24),4583Med Sci Monit.2019, 25:9499-9508Int J Food Sci Nutr.2019, 70(7):825-833Br J Pharmacol.2020, 10.1111Food and Chemical Toxicology...2020...Neurochem Int.2020, 133:104629
Our products had been exported to the following research institutions and universities, And still growing.
Auburn University (USA)University of Stirling (United Kingdom)Massachusetts General Hospital (USA)Shanghai Institute of Biochemis... (China)
Copenhagen University (Denmark)University of Vienna (Austria)Chulalongkorn University (Thailand)The Ohio State University (USA)
Mahidol University (Thailand)Indian Institute of Science (India)St. Jude Children Research Hosp... (USA)
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Alkaloids Compound Library
|| Nicotine 1'-N-oxide is a natural product from tobacco smoke. |
Nicotine 1'-N-oxide Description
||From tobacco smoke.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
Recent ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Chromatogr. 1993 Feb 26;612(2):302-9. |
|Determination of nicotine and its main metabolites in urine by high-performance liquid chromatography.[Pubmed: 8468389]|
METHODS AND RESULTS:
Nicotine and its main metabolites (cotinine, trans-3'-hydroxycotinine, trans-3'-hydroxycotinine glucuronide, Nicotine 1'-N-oxide and 3-pyridylcarbinol) were analysed in urine after liquid-liquid extraction by high-performance liquid chromatography using norephedrine as internal standard, ultraviolet detection at 260 nm and scanning ultraviolet spectra with a photodiode-array detector. The conjugated trans-3'-hydroxycotinine was determined after enzymatic hydrolysis. Specific determination of 3-pyridylcarbinol was also carried out. Owing to its good selectivity, sensitivity and reproducibility, the method was applied to the analysis of urine samples from smokers and non-smokers.
The results obtained suggest that the urinary markers used to assess active smoking or exposure to environmental tobacco smoke must be not only nicotine and cotinine, but also their main free and conjugated metabolites.