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    Saikosaponin H
    Information
    CAS No. 91990-63-5 Price $318 / 5mg
    Catalog No.CFN90902Purity>=98%
    Molecular Weight927.12Type of CompoundTriterpenoids
    FormulaC48H78O17Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
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    Saikosaponin H Description
    Source: The roots of Bupleurum chinense
    Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.

    PMID: 29328914

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.

    PMID: 29149595

    Scientific Reports 2017 Dec 11;7(1):17332.
    doi: 10.1038/s41598-017-17427-6.

    PMID: 29230013

    Molecules. 2017 Oct 27;22(11). pii: E1829.
    doi: 10.3390/molecules22111829.

    PMID: 29077044

    J Cell Biochem. 2018 Feb;119(2):2231-2239.
    doi: 10.1002/jcb.26385.

    PMID: 28857247

    Phytomedicine. 2018 Feb 1;40:37-47.
    doi: 10.1016/j.phymed.2017.12.030.

    PMID: 29496173
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.0786 mL 5.393 mL 10.7861 mL 21.5722 mL 26.9652 mL
    5 mM 0.2157 mL 1.0786 mL 2.1572 mL 4.3144 mL 5.393 mL
    10 mM 0.1079 mL 0.5393 mL 1.0786 mL 2.1572 mL 2.6965 mL
    50 mM 0.0216 mL 0.1079 mL 0.2157 mL 0.4314 mL 0.5393 mL
    100 mM 0.0108 mL 0.0539 mL 0.1079 mL 0.2157 mL 0.2697 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Saikosaponin H References Information
    Citation [1]

    Journal of Pharmaceutical Investigation,2008,38(1):57-61.

    Determination of saikosaponin derivatives in Bupleuri Radix using HPLC-ELSD.[Reference: WebLink]
    A HPLC-ELSD method was developed to determine saikosaponin derivatives from Bupleuri Radix. Eight saikosaponins, saikosaponin c, saikosaponin i, Saikosaponin H, saikosaponin a, saikosaponin b1, saikosaponin g, saikosaponin b2, and saikosaponin d, were analyzed under optimized HPLC conditions [column: Eclipse XDB (i.d., ; mobile phase: with 0.1% COOH (v/v) for solvent A and AcCN with 0.1% COOH (v/v) for solvent B, gradient elution; flow rate: 1mL/min; injection volume: ]. Good linearity was achieved in the range from 62.5 to for each compound, and intra-day precision and accuracy at each concentration level varied between 0.05 and 5.45% and between 93.9 and 109.6%, respectively, whereas those for inter-day variations were between 0.91 to 2.73% and 94.3 to 106.1%. This HPLC-ELSD method was applied for the determination of sakosaponins from Bupleuri Radix samples, and saikosaponin a , c and d were observed as major compounds. The other saikosaponins were shown under limit of quantification level thus couldn't be quantified. The present study suggested that the introduced HPLC-ELSD method is selective and reliable, and not only saikosaponin a, but also saikosaponin c and d should be employed as the standard markers for Bupleuri Radix.