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    Sequosempervirin D
    Sequosempervirin D
    Information
    CAS No. 864719-19-7 Price
    Catalog No.CFN97603Purity>=98%
    Molecular Weight356.42Type of CompoundLignans
    FormulaC21H24O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Description: Sequosempervirin D is a natural product from Sequoia sempervirens.
    In vitro:
    Chem Biodivers. 2005 Apr;2(4):497-505.
    Norlignans from Sequoia sempervirens.[Pubmed: 17191998 ]

    METHODS AND RESULTS:
    Six new norlignans, named sequosempervirin B, sequosempervirin C, Sequosempervirin D, sequosempervirin E, sequosempervirin F, sequosempervirin G (1-6), together with three known norlignans, agatharesinol (7), agatharesinol acetonide (8), and sugiresinol (9), were isolated from the branches and leaves of Sequoia sempervirens. Their structures were determined mainly by high-resolution mass spectroscopy (HR-MS), and various 1D- and 2D-NMR methods, as well as, in the case of 1, by means of X-ray diffraction.
    CONCLUSIONS:
    Compound 8 showed anticancer activity towards the A549 non-small-cell lung-cancer cell line (IC50 = 27.1 microM). The acetone extract of S. sempervirens was found to be antifungal towards Candida glabrata (IC50 = 15.98 microg/ml), and both the acetone and MeOH extracts inhibited the proteolytic activity of cathepsin B (IC50 = 4.58 and 5.49 microg/ml, resp.).
    Sequosempervirin D Description
    Source: The heartwoods of Sequoia sempervirens
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.8057 mL 14.0284 mL 28.0568 mL 56.1136 mL 70.142 mL
    5 mM 0.5611 mL 2.8057 mL 5.6114 mL 11.2227 mL 14.0284 mL
    10 mM 0.2806 mL 1.4028 mL 2.8057 mL 5.6114 mL 7.0142 mL
    50 mM 0.0561 mL 0.2806 mL 0.5611 mL 1.1223 mL 1.4028 mL
    100 mM 0.0281 mL 0.1403 mL 0.2806 mL 0.5611 mL 0.7014 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.