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    Natural Products
    Shegansu B
    Information
    CAS No. 291535-65-4 Price
    Catalog No.CFN92424Purity>=98%
    Molecular Weight514.5Type of CompoundPhenols
    FormulaC30H26O8Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)
    Citing Use of our Products
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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  • Biological Activity
    Description: Shegansu B exhibits significant in vitro anti-influenza viral activity in MDCK cells.
    Targets: Influenza virus
    In vitro:
    Planta Med. 2010 Nov;76(16):1874-6.
    In vitro anti-influenza viral activities of stilbenoids from the lianas of Gnetum pendulum.[Pubmed: 20539973]

    METHODS AND RESULTS:
    The anti-influenza viral activities of six stilbenoids from the lianas of Gnetum pendulum C. Y. Cheng were evaluated with two different assays, neuraminidase (NA) activity assay and cytopathic effect (CPE) reduction assay.
    CONCLUSIONS:
    The NA assay results showed that all six stilbenoids exerted an NA inhibitory effect, while the CPE assay indicated that among them, isorhapontigenin (2), gnetupendin B (3), Shegansu B (4), and gnetin D 6) exhibit significant in vitro anti-influenza viral activity in MDCK cells, with IC(50) values from 0.67 to 11.99 µg/mL in comparison to the positive controls oseltamivir acid and ribavirin whose IC(50) values were 0.040 and 5.54 µg/mL, respectively.
    Shegansu B Description
    Source: The herbs of Gnetum montanum Markgr.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    IF=36.216(2019)

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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 1.9436 mL 9.7182 mL 19.4363 mL 38.8727 mL 48.5909 mL
    5 mM 0.3887 mL 1.9436 mL 3.8873 mL 7.7745 mL 9.7182 mL
    10 mM 0.1944 mL 0.9718 mL 1.9436 mL 3.8873 mL 4.8591 mL
    50 mM 0.0389 mL 0.1944 mL 0.3887 mL 0.7775 mL 0.9718 mL
    100 mM 0.0194 mL 0.0972 mL 0.1944 mL 0.3887 mL 0.4859 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2000;2(3):169-75.
    A new stilbene dimer--shegansu B from Belamcanda chinensis.[Pubmed: 11256690]

    METHODS AND RESULTS:
    A new dimeric stilbene, named Shegansu B (1) was isolated from the ethanolic extract of the roots of Belamtantida chinensis (L.) DC., along with the known compounds isorhapontigenin, resveratol, p-hydroxybenzoic acid, iridin, tectoridin, tectorigenin and daucosterol. The structures were elucidated by means of spectroscopic evidence including 2D-NMR studies.