Gynostemma pentaphyllum, also called jiaogulan is an herbaceous vine of the family Cucurbitaceae (cucumber or gourd family) indigenous to the southern reaches of China, northern Vietnam, southern Korea, and Japan. Jiaogulan is best known as an herbal medicine reputed to have powerful antioxidant and adaptogenic effects purported to increase longevity.

Clinical research has indicated a number of therapeutic qualities of Jiaogulan, such as lowering cholesterol and high blood pressure, strengthening immunity, and inhibiting cancer growth.
The plant is best known for its use as an herbal medicine. It has not seen widespread use in traditional Chinese medicine (TCM) because it grows far from central China where TCM evolved; consequently, it was not included in the standard pharmacopoeia of the TCM system.

Jiaogulan is most often consumed as an herbal tea, and is also available as an alcohol extract and in capsule or pill form.