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    Natural Products
    1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
    1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
    Information
    CAS No. 776325-66-7 Price
    Catalog No.CFN97260Purity>=98%
    Molecular Weight396.4 Type of CompoundXanthones
    FormulaC23H24O6Physical DescriptionYellow powder
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    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

    1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
    Product Name 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone
    CAS No.: 776325-66-7
    Catalog No.: CFN97260
    Molecular Formula: C23H24O6
    Molecular Weight: 396.4 g/mol
    Purity: >=98%
    Type of Compound: Xanthones
    Physical Desc.: Yellow powder
    Source: The herbs of Garcinia xanthochymus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
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  • Biochemistry.2018, 57(40):5886-5896
  • PLoS One.2020, 15(2):e0220084.
  • Process Biochemistry2019, 87:213-220
  • J Chromatogr Sci.2015, 53(5):824-9
  • Chem. of Vegetable Raw Materials2020, 97-105
  • Sci Rep.2017, 7(1):3249
  • Psychopharmacology (Berl).2020, 10.1007
  • Molecules.2020, 25(15):3353.
  • Molecules.2016, 21(6)
  • Appl. Sci.2020, 10(16),5482.
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cytotoxic Compound Library
  • Xanthones Compound Library
  • Biological Activity
    Description: 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.
    In vitro:
    Chem Biodivers. 2007 May;4(5):940-6.
    Cytotoxic prenylated phenolic compounds from the twig bark of Garcinia xanthochymus.[Pubmed: 17511007]

    METHODS AND RESULTS:
    Three new hydroxylated xanthones with prenyl or geranyl substituents, compounds 1-3, were isolated from the twig bark of Garcinia xanthochymus, along with the four known compounds 1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone (4), 1,3,5,6-tetrahydroxy-4,7,8-triprenylxanthone (5), garciniaxanthone E (6), and 6-prenylapigenin (7). Their structures were elucidated by extensive spectroscopic analysis, including 1D- and 2D-NMR as well as HR-MS experiments.
    CONCLUSIONS:
    All compounds showed moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacked antifungal activity against Candida albicans.
    1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone Description
    Source: The herbs of Garcinia xanthochymus
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.5227 mL 12.6135 mL 25.227 mL 50.4541 mL 63.0676 mL
    5 mM 0.5045 mL 2.5227 mL 5.0454 mL 10.0908 mL 12.6135 mL
    10 mM 0.2523 mL 1.2614 mL 2.5227 mL 5.0454 mL 6.3068 mL
    50 mM 0.0505 mL 0.2523 mL 0.5045 mL 1.0091 mL 1.2614 mL
    100 mM 0.0252 mL 0.1261 mL 0.2523 mL 0.5045 mL 0.6307 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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