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2,3-Dihydroxy-12-oleanen-28-oic acid
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2,3-Dihydroxy-12-oleanen-28-oic acid
Price:
CAS No.: 26563-68-8
Catalog No.: CFN98310
Molecular Formula: C30H48O4
Molecular Weight: 472.7 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Rhododendron anthopogonoides Maxim
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
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Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: 2,3-Dihydroxy-olean-12-en-28-oic acids show a low cytotoxicity towards several human tumor cell lines.
In vitro:
Tetrahedron,2015,71(45):8528-34.
Straightforward partial synthesis of four diastereomeric 2,3-dihydroxy-olean-12-en-28-oic acids from oleanolic acid[Reference: WebLink]

METHODS AND RESULTS:
The four diastereomeric 2,3-dihydroxy-olean-12-en-28-oic acids (maslinic, augustic, bredemolic and 3-epi-maslinic acid) were easily accessed from one single starting material, oleanolic acid. The procedures allow the medium-to-large scale preparation of these valuable starting materials.
CONCLUSIONS:
Except for maslinic acid, the triterpenoic acids showed only a low cytotoxicity towards several human tumor cell lines.
2,3-Dihydroxy-12-oleanen-28-oic acid Description
Source: The herbs of Rhododendron anthopogonoides Maxim
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 2.1155 mL 10.5775 mL 21.1551 mL 42.3101 mL 52.8877 mL
5 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
10 mM 0.2116 mL 1.0578 mL 2.1155 mL 4.231 mL 5.2888 mL
50 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4231 mL 0.5289 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Asian Nat Prod Res. 2014;16(7):753-8.
Odorasides A and B, new sphingolipid glucosides from Klienia odora.[Pubmed: 24800634 ]

METHODS AND RESULTS:
Two new sphingolipid glucosides, odoraside A (1) and odoraside B (2), have been isolated from chloroform-soluble fraction of the total methanolic extract of Klienia odora, together with five known compounds, β-sitosterol (3), oleanolic acid (4), betulone (5), 2,3-Dihydroxy-12-oleanen-28-oic acid (6), and β-sitosterol 3-O-β-d-glucopyranoside (7).
CONCLUSIONS:
Their structures were assigned from (1)H and (13)C NMR spectra, DEPT and by 2D COSY, NOESY, HMQC, and HMBC experiments.
Capsaicin

Catalog No: CFN99917
CAS No: 404-86-4
Price: $50/20mg
Clerosterol

Catalog No: CFN90787
CAS No: 2364-23-0
Price: $ / mg
Isoliquiritin

Catalog No: CFN99155
CAS No: 5041-81-6
Price: $100/20mg
Mogroside IIe

Catalog No: CFN92191
CAS No: 88901-38-6
Price: $218/10mg
Syringetin

Catalog No: CFN70363
CAS No: 4423-37-4
Price: $ / mg
Diosgenin

Catalog No: CFN99515
CAS No: 512-04-9
Price: $30/20mg
Licoricesaponin G2

Catalog No: CFN92915
CAS No: 118441-84-2
Price: $368/20mg
Tormentic acid

Catalog No: CFN99434
CAS No: 13850-16-3
Price: $238/10mg
Tricin

Catalog No: CFN98841
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Picrasidine I

Catalog No: CFN99019
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