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    Natural Products
    2,3-Dihydroxy-12-oleanen-28-oic acid
    Information
    CAS No. 26563-68-8 Price
    Catalog No.CFN98310Purity>=98%
    Molecular Weight472.7 Type of CompoundTriterpenoids
    FormulaC30H48O4Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    2,3-Dihydroxy-12-oleanen-28-oic acid

    2,3-Dihydroxy-12-oleanen-28-oic acid
    Product Name 2,3-Dihydroxy-12-oleanen-28-oic acid
    CAS No.: 26563-68-8
    Catalog No.: CFN98310
    Molecular Formula: C30H48O4
    Molecular Weight: 472.7 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The herbs of Rhododendron anthopogonoides Maxim
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: 2,3-Dihydroxy-olean-12-en-28-oic acids show a low cytotoxicity towards several human tumor cell lines.
    In vitro:
    Tetrahedron,2015,71(45):8528-34.
    Straightforward partial synthesis of four diastereomeric 2,3-dihydroxy-olean-12-en-28-oic acids from oleanolic acid[Reference: WebLink]

    METHODS AND RESULTS:
    The four diastereomeric 2,3-dihydroxy-olean-12-en-28-oic acids (maslinic, augustic, bredemolic and 3-epi-maslinic acid) were easily accessed from one single starting material, oleanolic acid. The procedures allow the medium-to-large scale preparation of these valuable starting materials.
    CONCLUSIONS:
    Except for maslinic acid, the triterpenoic acids showed only a low cytotoxicity towards several human tumor cell lines.
    2,3-Dihydroxy-12-oleanen-28-oic acid Description
    Source: The herbs of Rhododendron anthopogonoides Maxim
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Cell. 2018 Jan 11;172(1-2):249-261.e12.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.1155 mL 10.5775 mL 21.1551 mL 42.3101 mL 52.8877 mL
    5 mM 0.4231 mL 2.1155 mL 4.231 mL 8.462 mL 10.5775 mL
    10 mM 0.2116 mL 1.0578 mL 2.1155 mL 4.231 mL 5.2888 mL
    50 mM 0.0423 mL 0.2116 mL 0.4231 mL 0.8462 mL 1.0578 mL
    100 mM 0.0212 mL 0.1058 mL 0.2116 mL 0.4231 mL 0.5289 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Asian Nat Prod Res. 2014;16(7):753-8.
    Odorasides A and B, new sphingolipid glucosides from Klienia odora.[Pubmed: 24800634 ]

    METHODS AND RESULTS:
    Two new sphingolipid glucosides, odoraside A (1) and odoraside B (2), have been isolated from chloroform-soluble fraction of the total methanolic extract of Klienia odora, together with five known compounds, β-sitosterol (3), oleanolic acid (4), betulone (5), 2,3-Dihydroxy-12-oleanen-28-oic acid (6), and β-sitosterol 3-O-β-d-glucopyranoside (7).
    CONCLUSIONS:
    Their structures were assigned from (1)H and (13)C NMR spectra, DEPT and by 2D COSY, NOESY, HMQC, and HMBC experiments.
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