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2-Hydroxy-3-methoxybenzoic acid glucose ester
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|Size /Price /Stock
||10 mM * 1 mL in DMSO / $227.8 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
New Zealand J. Forestry Sci.2014, 44:17Pharmacogn Mag.2015, 11:S585-91Molecules.2015, 20(10):19172-88Planta Med.2016, 82(13):1208-16Free Radic Biol Med.2017, 112:191-199Pharmacol Rep.2017, 69(6):1224-1231Food Res Int.2017, 96:40-45Phys Chem Chem Phys....2018...
Molecules.2018, 23(9):E2121International Food Research Journ...2018...Korean Journal of Pharmacognosy...2018...Biochem Biophys Res Commun....2018...Nutr Metab (Lond).2019, 16:31J Nat Med.2020, 74(1):65-75Toxins (Basel).2020, 12(4):210. South African J of Botany...2020...
Food Chem.2020, 327:126992.Bull. Pharm. Sci., Assiut Univers...2020...Dicle Tip Dergisi2020, 47(2),423-430.Korean Herb. Med. Inf....2020...Biology (Basel).2020, 9(11):363. Analytical Letters.2020, doi 10.1008Institut Pasteur Korea...2020...
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Ain Shams University (Egypt)Mahatma Gandhi University (India)University of Limpopo (South Africa)University of Malaya (Malaysia)
University of Toulouse (France)University of Eastern Finland (Finland)Auburn University (USA)Massachusetts General Hospital (USA)
Uniwersytet Medyczny w ?odzi (Poland)Pennsylvania State University (USA)University of Maryland School o... (USA)
2-Hydroxy-3-methoxybenzoic acid glucose ester
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Pharm Biomed Anal2016, 118:183-194Saudi Pharm J2020, 10.1016Molecules.2019, 24(11):E2044J Basic Clin Physiol Pharmacol.2016, 27(1):1-8Asian J Beauty Cosmetol2016, 14(3):249-257Front Immunol.2017, 8:1542The Japan Society for Analytical Chemistry2018, 67(4):201-206Org Biomol Chem.2017, 15(31):6483-6492Ulm University Medical Center2020, doi: 10.18725.J Med Food.2019, 22(10):1067-1077
Related Screening Libraries
||2-Hydroxy-3-methoxybenzoic acid glucose ester shows a potent antagonistic activity against platelet activating factor (PAF), it can prevent the mice from the PAF-induced death at a dose of 300 micrograms/mouse. |
|Arch Pharm Res. 1998 Aug;21(4):436-9. |
|PAF antagonistic activity of 2-hydroxy-3-methoxybenzoic acid glucose ester from Gentiana scabra.[Pubmed: 9875472]|
|In order to find out anti-platelet activating factor (PAF) from natural resources, Korean medicinal plants used for the treatments of peripheral circulation disorders were tested for their possible protective effects on PAF-induced anaphylactic shock.
METHODS AND RESULTS:
From the above screening, the methanol extract of Gentiana scabra showed a potent antagonistic activity against PAF. Water suspension of the extract was partitioned with CH2Cl2 and EtOAc, successively. The EtOAc fraction which showed the highest activity was chromatographed on silica gel to yield 6 fractions. From the fraction which showed higher PAF-antagonistic activity than the other fractions, compound 1 was isolated by recrystallization.
On the basis of spectral data, compound 1 was identified as 2-Hydroxy-3-methoxybenzoic acid glucose ester. The compound prevented the mice from the PAF-induced death at a dose of 300 micrograms/mouse.
2-Hydroxy-3-methoxybenzoic acid glucose ester Description
||The whole plants of Gentiana scabra.
||DMSO, Pyridine, Methanol, Ethanol, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
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||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.