Science | Nature | Cell | View More
Natural Products
2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone)
2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone)
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone)
Price:
CAS No.: 111316-17-7
Catalog No.: CFN91680
Molecular Formula: C16H16O5
Molecular Weight: 288.3 g/mol
Purity: >=98%
Type of Compound: Chalcones
Physical Desc.: Powder
Source: The peels of apple.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Wuerzburg (Germany)
  • University of Pretoria (South Africa)
  • Anna University (India)
  • University of Perugia (Italy)
  • University of the Basque Country (Spain)
  • Lund University (Sweden)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Vin?a Institute of Nuclear Scie... (Serbia)
  • VIB Department of Plant Systems... (Belgium)
  • University of British Columbia (Canada)
  • Universite de Lille1 (France)
  • More...
Package
Featured Products
Eupatorin

Catalog No: CFN97418
CAS No: 855-96-9
Price: $158/10mg
Dihydrotanshinone I

Catalog No: CFN97435
CAS No: 87205-99-0
Price: $60/20mg
Geniposidic acid

Catalog No: CFN98337
CAS No: 27741-01-1
Price: $30/20mg
N-p-trans-Coumaroyltyramine

Catalog No: CFN98494
CAS No: 36417-86-4
Price: $268/10mg
Dehydroevodiamine

Catalog No: CFN90944
CAS No: 67909-49-3
Price: $50/20mg
o-Methoxycinnamaldehyde

Catalog No: CFN93299
CAS No: 1504-74-1
Price: $40/20mg
Panaxydol

Catalog No: CFN92797
CAS No: 72800-72-7
Price: $448/20mg
Deapi-platycodin D

Catalog No: CFN90472
CAS No: 78763-58-3
Price: $268/10mg
Cordycepin

Catalog No: CFN98566
CAS No: 73-03-0
Price: $40/20mg
20-Hydroxyecdysone

Catalog No: CFN98873
CAS No: 5289-74-7
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) Description
Source: The peels of apple.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
(3E,5E,11E)-tridecatriene-7,9-diyn...

Catalog No: CFN95191
CAS No: N/A
Price: $318/5mg
Lariciresinol 4-O-glucoside

Catalog No: CFN95389
CAS No: 143663-00-7
Price: $318/5mg
1,2-Epoxy-10(14)-furanogermacren-6...

Catalog No: CFN95214
CAS No: 383368-24-9
Price: $318/10mg
Ganolucidic acid D

Catalog No: CFN95472
CAS No: 102607-22-7
Price: $413/5mg
5-O-Coumaroylquinic acid

Catalog No: CFN95507
CAS No: 32451-86-8
Price: $318/5mg
Umbelliferone 7-O-rutinoside

Catalog No: CFN95431
CAS No: 135064-04-9
Price: $318/10mg
Isomargaritene

Catalog No: CFN95304
CAS No: 64271-11-0
Price: $318/10mg
Ganoderic acid J

Catalog No: CFN95516
CAS No: 100440-26-4
Price: $318/10mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.4686 mL 17.343 mL 34.6861 mL 69.3722 mL 86.7152 mL
5 mM 0.6937 mL 3.4686 mL 6.9372 mL 13.8744 mL 17.343 mL
10 mM 0.3469 mL 1.7343 mL 3.4686 mL 6.9372 mL 8.6715 mL
50 mM 0.0694 mL 0.3469 mL 0.6937 mL 1.3874 mL 1.7343 mL
100 mM 0.0347 mL 0.1734 mL 0.3469 mL 0.6937 mL 0.8672 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
J Agric Food Chem . 2003 May 21;51(11):3309-3312.
Dihydrochalcones: evaluation as novel radical scavenging antioxidants[Pubmed: 12744659]
Dihydrochalcones are a family of bicyclic flavonoids, defined by the presence of two benzene rings joined by a saturated three carbon bridge. In the present study, we systematically examined the antioxidant activities of dihydrochalcones against the stable free radical (1,1-diphenyl-2-picrylhydrazyl) and lipid peroxidation in the erythrocyte membrane. All dihydrochalcones exhibited higher antioxidant activities than the corresponding flavanones. The (1)H NMR analysis indicated that the active dihydrochalcone has a time-averaged conformation in which the aromatic A ring is orthogonal to the carbonyl group, while the inactive dihydrochalcone such as 2'-O-methyl-phloretin has a strongly hydrogen-bonded phenolic hydroxyl group, suggestive of a coplanar conformation. A hydroxyl group at the 2'-position of the dihydrochalcone A ring, newly formed by reduction of the flavanone C ring, is an essential pharmacophore for its radical scavenging potential.
Phytochemistry . 2000 Nov;55(5):439-446.
(Rel)-1beta,2alpha-di-(2,4-dihydroxy-6-methoxybenzoyl)-3beta, 4alpha-di-(4-methoxyphenyl)-cyclobutane and other flavonoids from the aerial parts of Goniothalamus gardneri and Goniothalamus thwaitesii[Pubmed: 11140605]
The aerial parts of Goniothalamus gardneri (Annonaceae) has yielded the known flavonoids 2'-hydroxy-4,4',6'-trimethoxychalcone (flavokawain A), 2',4'-dihydroxy-4,6'-dimethoxydihydrochalcone, 4,2',4'-trihydroxy-6'-methoxydihydrochalcone, 5,7,4'-trimethoxyflavanone (naringenin trimethyl ether) and 7-hydroxy-5,4'-dimethoxyflavanone (tsugafolin) together with three novel compounds, the dimer characterised as (rel)-1beta,2alpha-di-(2,4-dihydroxy-6-methoxybenzoyl)-3beta,4alpha-di-(4-methoxyphenyl)-cyclobutane, 2',4'-dihydroxy-4,6'-dimethoxychalcone and 2'-hydroxy-4,4',6'-trimethoxydihydrochalcone. The last two have previously been synthesised but appear to be new natural products. A similar study of the aerial parts of G. thwaitesii led only to the isolation of the known flavonoids myricetin 4'-O-methyl ether-3-O-alpha-L-rhamnopyranoside (mearnsitrin) and myricetin-3-O-methyl ether (annulatin), together with the triterpenes friedelinol, friedelin and betulinic acid. All compounds were identified by spectroscopic analysis and, for known compounds, by comparison with published data.
Eupatorin

Catalog No: CFN97418
CAS No: 855-96-9
Price: $158/10mg
Dihydrotanshinone I

Catalog No: CFN97435
CAS No: 87205-99-0
Price: $60/20mg
Geniposidic acid

Catalog No: CFN98337
CAS No: 27741-01-1
Price: $30/20mg
N-p-trans-Coumaroyltyramine

Catalog No: CFN98494
CAS No: 36417-86-4
Price: $268/10mg
Dehydroevodiamine

Catalog No: CFN90944
CAS No: 67909-49-3
Price: $50/20mg
o-Methoxycinnamaldehyde

Catalog No: CFN93299
CAS No: 1504-74-1
Price: $40/20mg
Panaxydol

Catalog No: CFN92797
CAS No: 72800-72-7
Price: $448/20mg
Deapi-platycodin D

Catalog No: CFN90472
CAS No: 78763-58-3
Price: $268/10mg
Cordycepin

Catalog No: CFN98566
CAS No: 73-03-0
Price: $40/20mg
20-Hydroxyecdysone

Catalog No: CFN98873
CAS No: 5289-74-7
Price: $40/20mg
Tags: buy 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) | 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) supplier | purchase 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) | 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) cost | 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) manufacturer | order 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) | 2'-O-Methylphloretin (4,2',4'-Trihydroxy-6'-methoxydihydrochalcone) distributor