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    Natural Products
    Maculosidin
    Maculosidin
    Information
    CAS No. 522-19-0 Price $413 / 5mg
    Catalog No.CFN95126Purity>=98%
    Molecular Weight259.3Type of CompoundAlkaloids
    FormulaC14H13NO4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $289.1 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Maculosidin

    Maculosidin
    Product Name Maculosidin
    CAS No.: 522-19-0
    Catalog No.: CFN95126
    Molecular Formula: C14H13NO4
    Molecular Weight: 259.3 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The herbs of Esenbeckia litoralis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $413 / 5mg
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  • Molecules.2020, 25(23):5556.
  • J Agric Food Chem.2016, 64(35):6783-90
  • Neuropharmacology2019, 151437
  • Nutrients.2018, 10(10)
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  • Evid Based Complement Alternat Med.2017, 2017:6360836
  • Natural Product Communications2020, doi: 10.1177.
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  • Eur Rev Med Pharmacol Sci.2020, 24(9):5127-5139.
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Biological Activity
    Description: Maculosidine affect the PS I electron acceptors on leaf discs, it can inhibit ATP synthesis, basal, phosphorylating and uncoupled electron transport acting as Hill reaction inhibitors on spinach chloroplasts.
    In vitro:
    Phytochemistry. 1999 Sep;52(1):95-8.
    Quinoline alkaloids from Acronychia laurifolia.[Pubmed: 10466225 ]

    METHODS AND RESULTS:
    In the search for natural inhibitors of plant growth, we investigate the mechanism of action of the natural furoquinoline alkaloids isolated from Balfourodendron riedelianum (Rutaceae): evolitrine (1), kokusaginine (2), γ-fagarine (3), skimmianine (4) and Maculosidine (5) on the photosynthesis light reactions. Their effect on the electron transport chain on thylakoids was analyzed. Alkaloids 1, 2, 4 and 5 inhibited ATP synthesis, basal, phosphorylating and uncoupled electron transport acting as Hill reaction inhibitors on spinach chloroplasts. Alkaloid 3 was not active. The inhibition and interaction site of alkaloids 1, 2, 4 and 5 on the non-cyclic electron transport chain was studied by polarography and fluorescence of the chlorophyll a (Chl a).
    CONCLUSIONS:
    The results indicate that the target for 1 was localized on the donor and acceptor side of PS II. In addition alkaloids 2 and 5 affect the PS I electron acceptors on leaf discs.
    Maculosidin Description
    Source: The herbs of Esenbeckia litoralis
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.8565 mL 19.2827 mL 38.5654 mL 77.1307 mL 96.4134 mL
    5 mM 0.7713 mL 3.8565 mL 7.7131 mL 15.4261 mL 19.2827 mL
    10 mM 0.3857 mL 1.9283 mL 3.8565 mL 7.7131 mL 9.6413 mL
    50 mM 0.0771 mL 0.3857 mL 0.7713 mL 1.5426 mL 1.9283 mL
    100 mM 0.0386 mL 0.1928 mL 0.3857 mL 0.7713 mL 0.9641 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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