Science | Nature | Cell | View More
Natural Products
20R-Ginsenoside Rg2
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name 20R-Ginsenoside Rg2
Price: $218 / 20mg
CAS No.: 80952-72-3
Catalog No.: CFN90412
Molecular Formula: C42H72O13
Molecular Weight: 785.02 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The roots of Panax ginseng C. A. Mey.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $55.9 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Wuerzburg (Germany)
  • St. Jude Children Research Hosp... (USA)
  • Instytut Nawozów Sztucznych w ... (Poland)
  • National Cancer Institute (USA)
  • University of Lodz (Poland)
  • Florida International University (USA)
  • Universitas islam negeri Jakarta (Indonesia)
  • Cancer Research Initatives Foun... (Malaysia)
  • University of Eastern Finland (Finland)
  • Seoul National University of Sc... (Korea)
  • University of Sao Paulo (Brazil)
  • More...
Package
Featured Products
Benzoylmesaconine

Catalog No: CFN98575
CAS No: 63238-67-5
Price: $168/20mg
3-Isomangostin

Catalog No: CFN99724
CAS No: 19275-46-8
Price: $168/10mg
Salvianolic acid A

Catalog No: CFN99161
CAS No: 96574-01-5
Price: $128/20mg
Angelicin

Catalog No: CFN98854
CAS No: 523-50-2
Price: $30/20mg
Integerrimine

Catalog No: CFN00419
CAS No: 480-79-5
Price: $ /
Quercetin 3-O-glucoside-7-O-rhamno...

Catalog No: CFN90738
CAS No: 18016-58-5
Price: $538/5mg
Bakuchiol

Catalog No: CFN99047
CAS No: 10309-37-2
Price: $40/20mg
Pterostilbene

Catalog No: CFN90397
CAS No: 537-42-8
Price: $40/20mg
Arctigenin 4'-O-beta-gentiobioside

Catalog No: CFN90714
CAS No: 41682-24-0
Price: $268/5mg
Carnosic acid

Catalog No: CFN99102
CAS No: 3650-09-7
Price: $40/20mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Ginsenoside Rg2 may have a therapeutic potential for type 2 diabetic patients, it suppresses the hepatic glucose production via AMPK-induced phosphorylation of GSK3βand induction of SHP gene expression .Ginsenoside Rg2 can protect H9c2 cells against H2O2- induced injury through its actions of anti-oxidant and anti-apoptosis.20R-Ginsenoside Rg2 inhibits the cytokine interleukin 1 alpha (IL-1α)-induced reduction in gap junction-mediated intercellular communication (GJIC).
Targets: GSK-3 | IL Receptor | AMPK
In vitro:
Planta Med., 2001, 67(5):417-22.
Effects of ginsenosides from Panax ginseng on cell-to-cell communication function mediated by gap junctions.[Pubmed: 11488454 ]

METHODS AND RESULTS:
In the present study we examined the effects of 27 ginsenosides isolated from Panax ginseng on GJIC. The results show that compounds 1 (oleanolic acid), 2 (ginsenoside-R0), 3 (ginsenoside-Rb1), 5 (ginsenoside-Rb2), 7 (ginsenoside-Rd), 8 (ginsenoside-Rg3), 12 (panaxadial), 13 (notoginsenoside-R4), 17 [ginsenoside-Rg2 (20S)], 18 (ginsenoside-Rf), and 26 (ginsenoside-F3) did not obviously affect GJIC, whereas compounds 4 (ginsenoside-Rc), 6 (ginsenoside-Rb3), 9 (ginsenoside-Rd2), 10 (notoginsenoside-Fe), 11 (ginsenoside-Rh2),14 (ginsenoside-Ra1), 15 (ginsenoside-Re), 16 (20R-Ginsenoside Rg2 ), 19 (ginsenoside-Ia), 20 [ginsenoside-Rh1 (20S)], 21 [ginsenoside-Rh1 (20R)], 22 (ginsenoside-F1), 23 (protopanaxatriol), 24 (panaxatriol), 25 (ginsenoside-Rg1), and 27 (chikusetsaponin-L8) induced GJIC reductions at various degrees. Compounds 2, 7, and 8 protected against the tyrosine phosphatase inhibitor vanadate-induced GJIC reduction, while compounds 1, 5, 7, and 17 inhibited the cytokine interleukin 1 alpha (IL-1alpha)-induced reduction in GJIC. Nevertheless, no compounds protected against the protein kinase C (PKC) activator 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced GJIC inhibition. On the other hand, GJIC reductions induced by compounds 6, 9,10, 20, 21, 22, 24, and 25 were inhibited by the tyrosine kinase (TK) inhibitor genistein, while GJIC reductions induced by compounds 6, 9, 14, 16, 19, 21, and 24 were attenuated in the presence of the PKC inhibitor calphostin C. However, GJIC reductions induced by compounds 4, 23, and 27 were not inhibited either by genistein or by calphostin C.
CONCLUSIONS:
These data indicate that various mechanisms are responsible for effects of ginsenosides on GJIC.
20R-Ginsenoside Rg2 Description
Source: The roots of Panax ginseng C. A. Mey.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Euphorbia factor L24

Catalog No: CFN95334
CAS No: 1613700-13-2
Price: $318/5mg
Somnifericin

Catalog No: CFN95280
CAS No: 173693-57-7
Price: $318/5mg
Benzyl beta-D-glucopyranoside

Catalog No: CFN95427
CAS No: 4304-12-5
Price: $318/10mg
3'-Angeloyloxy-4'-senecioyloxy-2',...

Catalog No: CFN95123
CAS No: 1221686-60-7
Price: $398/5mg
Rhamnocitrin 3-glucoside

Catalog No: CFN95134
CAS No: 41545-37-3
Price: $318/10mg
Vanillic acid glucoside

Catalog No: CFN95257
CAS No: 32142-31-7
Price: $318/5mg
Methyl ganoderate A

Catalog No: CFN95550
CAS No: 105742-78-7
Price: $413/5mg
Lariciresinol 4-O-glucoside

Catalog No: CFN95389
CAS No: 143663-00-7
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.2739 mL 6.3693 mL 12.7385 mL 25.4771 mL 31.8463 mL
5 mM 0.2548 mL 1.2739 mL 2.5477 mL 5.0954 mL 6.3693 mL
10 mM 0.1274 mL 0.6369 mL 1.2739 mL 2.5477 mL 3.1846 mL
50 mM 0.0255 mL 0.1274 mL 0.2548 mL 0.5095 mL 0.6369 mL
100 mM 0.0127 mL 0.0637 mL 0.1274 mL 0.2548 mL 0.3185 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Benzoylmesaconine

Catalog No: CFN98575
CAS No: 63238-67-5
Price: $168/20mg
3-Isomangostin

Catalog No: CFN99724
CAS No: 19275-46-8
Price: $168/10mg
Salvianolic acid A

Catalog No: CFN99161
CAS No: 96574-01-5
Price: $128/20mg
Angelicin

Catalog No: CFN98854
CAS No: 523-50-2
Price: $30/20mg
Integerrimine

Catalog No: CFN00419
CAS No: 480-79-5
Price: $ /
Quercetin 3-O-glucoside-7-O-rhamno...

Catalog No: CFN90738
CAS No: 18016-58-5
Price: $538/5mg
Bakuchiol

Catalog No: CFN99047
CAS No: 10309-37-2
Price: $40/20mg
Pterostilbene

Catalog No: CFN90397
CAS No: 537-42-8
Price: $40/20mg
Arctigenin 4'-O-beta-gentiobioside

Catalog No: CFN90714
CAS No: 41682-24-0
Price: $268/5mg
Carnosic acid

Catalog No: CFN99102
CAS No: 3650-09-7
Price: $40/20mg
Tags: buy 20R-Ginsenoside Rg2 | 20R-Ginsenoside Rg2 supplier | purchase 20R-Ginsenoside Rg2 | 20R-Ginsenoside Rg2 cost | 20R-Ginsenoside Rg2 manufacturer | order 20R-Ginsenoside Rg2 | 20R-Ginsenoside Rg2 distributor