ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
SBRAS2016, 12Acta Chromatographica2016, 29(3)Biochem Systematics and Ecology...2017...Sci Rep. 2017, 12953(7)BMC Complement Altern Med....2017...J Ethnopharmacol.2017, 198:205-213FEMS Microbiol Lett.2017, 364(11)Front Plant Sci.2017, 8:723
Fitoterapia.2018, 124:92-102Food Quality and Safety2018, 2:213-219Saf Health Work.2019, 10(2):196-204Molecules.2019, 24(21):E3834Med Sci Monit.2019, 25:9499-9508Int Immunopharmacol.2019, 71:22-31Process Biochemistry2019, 87:213-220Br J Pharmacol.2020, 10.1111
Food and Chemical Toxicology...2020...J Sep Sci.2020, 201901140Biosci Biotechnol Biochem....2020...J of Apicultural Research2020, 10.1080Asian Pac J Cancer Prev. ...2020...J Biomed Sci.2020, 27(1):60.J of Pharmaceutical Analysis...2020...
More...
Our products had been exported to the following research institutions and universities, And still growing.
Korea Intitute of Science and T... (Korea)Almansora University (Egypt)Melbourne University (Australia)Uniwersytet Medyczny w ?odzi (Poland)
Utrecht University (Netherlands)Universidad de Antioquia (Colombia)Universidade de Franca (Brazil)Chulalongkorn University (Thailand)
Srinakharinwirot University (Thailand)The Ohio State University (USA)University of Indonesia (Indonesia)
More...
5,7,4'-Trimethoxyafzelechin
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
FASEB J.2019, 33(8):9685-9694Sci Rep. 2018, 1-9J Bone Miner Res.2017, 32(12):2415-2430Food Chem.2019, 290:286-294Institut Pasteur Korea2020, doi: 10.21203.J Pharm Biomed Anal.2016, 129:50-59Saudi Pharm J.2019, 27(1):145-153PLoS One.2017, 12(3):e0173585Journal of Third Military Medical University2018, 40(12):1073-1078Natural Product Communications2020, doi: 10.1177.
Related Screening Libraries
| Size /Price /Stock |
10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
|
Related Libraries |
Flavonoids Compound Library |
| Description: |
5,7,4'-Trimethoxyafzelechin is a natural product from Celastrus orbiculatus. |
5,7,4'-Trimethoxyafzelechin Description
| Source: |
The herbs of Celastrus orbiculatus |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.1611 mL |
15.8053 mL |
31.6106 mL |
63.2211 mL |
79.0264 mL |
| 5 mM |
0.6322 mL |
3.1611 mL |
6.3221 mL |
12.6442 mL |
15.8053 mL |
| 10 mM |
0.3161 mL |
1.5805 mL |
3.1611 mL |
6.3221 mL |
7.9026 mL |
| 50 mM |
0.0632 mL |
0.3161 mL |
0.6322 mL |
1.2644 mL |
1.5805 mL |
| 100 mM |
0.0316 mL |
0.1581 mL |
0.3161 mL |
0.6322 mL |
0.7903 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| J Oleo Sci. 2008;57(8):431-5. | | Alpha-glucosidase inhibitor from Bergenia ligulata.[Pubmed: 18622126] | Inhibitory compound of alpha-glucosidase activity, (+)-afzelechin (1), was isolated from rhizomes of Bergenia ligulata.
METHODS AND RESULTS:
The structure was identified by IR, EI-MS, (1)H and (13)C NMR spectroscopy. The ID(50) (50% inhibition dose) value of compound 1 was 0.13 mM. To investigate the structure-activity relationship, (+)-afzelechin tetraacetate (2), (+)-5,7,4'-Trimethoxyafzelechin (3), (+)-tetramethoxyafzelechin (4), and (+)-3-acetyl-5,7,4'-Trimethoxyafzelechin (5) as the derivatives of compound 1 were evaluated as well. |
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