ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $413 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Ind Crops Prod.2014, 62:173-178Molecules.2016, 21(6)Molecules.2017, 22(2)J.Acta Agriculturae Scandinavica...2017...Anal Chim Acta.2018, 1039:162-171Fitoterapia.2018, 124:92-102Neuropharmacology.2018, 131:68-82Molecules.2018, 23(11):E2837
International Food Research Journ...2018...Korean Journal of Pharmacognosy...2018...Arch Biochem Biophys.2018, 644:93-99Virulence.2018, 9(1):588-603Int J Mol Sci.2019, 20(8):E1855Molecules.2019, 24(10):E1930Saudi Pharm J.2019, 27(1):145-153Phytomedicine.2019, 62:152962
Food and Chemical Toxicology...2020...Evid-Based Compl Alt2020, 7202519:13Int J Mol Sci.2020, 21(19),7070.SCOPUS.2020, 836-847.Analytical Letters.2020, doi 10.1008American Association for Anatomy...2020...J Korean Soc Food Sci Nutr...2020...
Our products had been exported to the following research institutions and universities, And still growing.
The Institute of Cancer Research (United Kingdom)St. Jude Children Research Hosp... (USA)University of Toronto (Canada)Tohoku University (Japan)
Utrecht University (Netherlands)Imperial College London (United Kingdom)Korea Food Research Institute(K... (Korea)Utah State University (USA)
University of Toulouse (France)University of the Basque Country (Spain)Worcester Polytechnic Institute (USA)
6alpha-Hydroxypolyporenic acid C
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Planta Med.2018, 84(15):1101-1109Appl. Sci.2020, 10(4),1304Int. Conference on Med. Sci. and Bio.2017, 17973J Drug Target.2016, 24:1-28Am J Chin Med.2016, 44(8):1719-1735Biomedicine & Pharmacotherapy2020, 125:109950Molecules.2020, 25(18):4283.Evid Based Complement Alternat Med.2018, 2018:8565132Nat Commun.2019, 10(1):2745J. of Agricultural Science2015, 1916-9760
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Triterpenoids Compound Library
||6alpha-Hydroxypolyporenic acid C is a natural product from Wolfiporia cocos (Schw.) Ryv.|
|Zhongguo Zhong Yao Za Zhi. 2008 Jul;33(13):1596-601. |
|Absorption of triterpenoid compounds from Indian bread (Poria cocos) across human intestinal epithelial (Caco-2) cells in vitro.[Pubmed: 18837324]|
|To study the absorption of 3-epidehydrotumulosic acid (EDHTA), polyporenic acid C (PPAC) and 6alpha-Hydroxypolyporenic acid C (HPPA) isolated from the sclerotium of Poria cocos. In human intestinal epithelial. |
METHODS AND RESULTS:
By using Caco-2 (the human colonic adenocarcinoma cell lines) cells monolayer as an intestinal epithelial cell model, the permeability of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were studied from apical side (AP side) to basolateral side (BL side) or from BL side to AP side.The P(app) values of EDHTA and PPAC were at a nearly same magnitude with those of propranolol, and 6alpha-Hydroxypolyporenic acid C lied between those of propranolol and atenolol. On the other hand, the efflux transport of EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C were higher 1.78, 1.91 and 2. 47 times more than its influx transport with 0.56, 0.52 and 0.41 rate of P(app A --> B)/P(app (B --> A).
EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C can be absorbed across intestinal epithelial cells, among EDHTA and PPAC will be completely. 6alpha-Hydroxypolyporenic acid C will be moderately absorbed compounds. EDHTA, PPAC and 6alpha-Hydroxypolyporenic acid C may have been involved in efflux mechanism in Caco-2 cells monolayers model from the basolateral-to-apical direction.
6alpha-Hydroxypolyporenic acid C Description
||The roots of Wolfiporia cocos (Schw.) Ryv.
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.