7-Methoxy-4-methylcoumarin | CAS:2555-28-4

7-Methoxy-4-methylcoumarin

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Description:

7-Methoxy-4-methylcoumarin is a coumarin derivative and fluorescent label, it displays good activity against B. subtilis.

Targets:

Antifection

In vitro:

Pak J Pharm Sci. 2015 May;28(3):819-23.

Potential antibacterial activity of coumarin and coumarin-3-acetic acid derivatives[Reference: WebLink]

Coumarin and coumarin-3-acetic acid derivatives were synthesized by reacting phenols with malic acid, ethyl acetoacetate and ethyl acetylsuccinate in appropriate reaction conditions.
METHODS AND RESULTS:
All synthesized compounds were subjected to test for their antimicrobial activities against variety of gram positive (Bacillus subtilis, Staphylococcus aureus) and gram negative bacterial stains (Shigella sonnei, Escherichia coli) by agar dilution method. Several of them exhibited appreciable good antibacterial activity against the different strains of gram positive and gram negative bacteria. These findings suggest a great potential of these compounds for screening and use as antibacterial agents for further studies with a battery of bacteria. Minimal inhibitory concentration values shows that experimental compounds were found less active in comparison to standard drug ciprofloxacin but showed parallel activity to moxifloxacin. From table 3, it can be concluded that all the compounds have displayed good activity against B. subtilis.
CONCLUSIONS:
Compounds were enough active against this bacterial strain especially 7-Methoxy coumarin (1), 7-Methyl coumarin (4), 6-methylcoumarin (5), 4,6-Dimethylcoumarin (7), 7-Methoxy-4-methylcoumarin (8) and 7-Methoxy-4-methylcoumarin-3- acetic acid (17). 6-Methylcoumarin (5), 7-methoxy-4- methylcoumarin (8) and 6-aminocoumarin-3-acetic acid (12) showed excellent activities against B. subtilis even better than standard drug amoxifloxacin.

7-Methoxy-4-methylcoumarin Description

Source:	The herbs of Eupatorium pauciflorum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	7-Methoxy-4-methylcoumarin
Price:	$40 / 20mg
CAS No.:	2555-28-4
Catalog No.:	CFN94405
Molecular Formula:	C₁₁H₁₀O₃
Molecular Weight:	190.20 g/mol
Purity:	>=98%
Type of Compound:	Coumarins
Physical Desc.:	Powder
Source:	The herbs of Eupatorium pauciflorum.
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antibacterial Compound Library Markers Compound Library Coumarins Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	5.2576 mL	26.2881 mL	52.5762 mL	105.1525 mL	131.4406 mL
5 mM	1.0515 mL	5.2576 mL	10.5152 mL	21.0305 mL	26.2881 mL
10 mM	0.5258 mL	2.6288 mL	5.2576 mL	10.5152 mL	13.1441 mL
50 mM	0.1052 mL	0.5258 mL	1.0515 mL	2.103 mL	2.6288 mL
100 mM	0.0526 mL	0.2629 mL	0.5258 mL	1.0515 mL	1.3144 mL

CFN94405	7-Methoxy-4-methylcoumarin	2555-28-4	190.20	C₁₁H₁₀O₃
CFN94425	6-Methoxy-4-methylcoumarin	6295-35-8	190.20	C₁₁H₁₀O₃
CFN92538	4,6-Dimethoxy-2H-1-benzopyran-2-one	53666-78-7	206.2	C₁₁H₁₀O₄
CFN97084	4,6,7-Trimethoxy-5-methylcoumarin	62615-63-8	250.3	C₁₃H₁₄O₅
CFN96263	Edgeworin	120028-43-5	322.3	C₁₈H₁₀O₆
CFN90329	Daphnoretin	2034-69-7	352.3	C₁₉H₁₂O₇
CFN96604	Isodaphnoretin B	944824-29-7	382.32	C₂₀H₁₄O₈
CFN95207	Isoeuphorbetin	50677-55-9	354.3	C₁₈H₁₀O₈
CFN96473	Triumbelletin	131559-54-1	482.39	C₂₇H₁₄O₉
CFN97913	Mellein	480-33-1	178.2	C₁₀H₁₀O₃