Abrine | CAS:526-31-8; 21339-55-9 | Manufacturer ChemFaces

Abrine

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Size /Price /Stock	10 mM * 1 mL in DMSO / $8.9 / In-stock
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Description:

Abrine shows comparable ABTS radical cation scavenging activities and reduces power to two commercial antioxidants (BHT and Trolox).

In vitro:

Food Funct. 2014 Sep;5(9):2268-77.

In vitro antioxidant activities and anti-proliferative properties of the functional herb Abrus cantoniensis and its main alkaloid abrine.[Pubmed: 25059572 ]

Abrus cantoniensis is a common and popular vegetative food consumed as beverage, soup and folk medicine in the tropical and subtropical areas of Asia. It has been claimed valuable for cleansing toxicants in the liver. However, the functional effects of A. cantoniensis have not yet been scientifically explored. This study comprehensively evaluated the in vitro antioxidant and anti-proliferative capacities of the herbal extract and the main alkaloid Abrine.
METHODS AND RESULTS:
Abrine was qualitatively and quantitatively determined in methanol extract (ME) using HPLC-DAD and LC-MS/MS. The results showed that ME, ethyl acetate fraction (EF) and Abrine exhibited comparable ABTS radical cation scavenging activities and reducing power to two commercial antioxidants (BHT and Trolox). The EF exerted strong cellular antioxidant activity and selective cytotoxicity against three cancer cell lines in a dose-dependent manner. Biological assays revealed that the EF induced cell cycle arrest at G2/M and apoptosis in MCF-7 and Hep3B cells after 48 h of treatment.
CONCLUSIONS:
Thus, A. cantoniensis exerted potent cellular antioxidant and anti-proliferative properties, highlighting why it has been traditionally used as a functional food.

Abrine Description

Source:	The seeds of Abrus precatorius
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Abrine
Price:	$30 / 20mg
CAS No.:	526-31-8; 21339-55-9
Catalog No.:	CFN90202
Molecular Formula:	C₁₂H₁₄N₂O₂
Molecular Weight:	218.25 g/mol
Purity:	>=98%
Type of Compound:	Alkaloids
Physical Desc.:	Powder
Source:	The seeds of Abrus precatorius
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Antioxidants Compound Library Alkaloids Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	4.5819 mL	22.9095 mL	45.819 mL	91.638 mL	114.5475 mL
5 mM	0.9164 mL	4.5819 mL	9.1638 mL	18.3276 mL	22.9095 mL
10 mM	0.4582 mL	2.291 mL	4.5819 mL	9.1638 mL	11.4548 mL
50 mM	0.0916 mL	0.4582 mL	0.9164 mL	1.8328 mL	2.291 mL
100 mM	0.0458 mL	0.2291 mL	0.4582 mL	0.9164 mL	1.1455 mL

CFN96036	1-Methoxyindole-3-carboxylic acid	91913-76-7	191.2	C₁₀H₉NO₃
CFN96052	Caulilexin C	30536-48-2	186.2	C₁₁H₁₀N₂O
CFN91557	N-Methylserotonin	1134-01-6	190.2	C₁₁H₁₄N₂O
CFN91430	Bufobutanoic acid	74010-65-4	276.3	C₁₄H₁₆N₂O₄
CFN98111	Gramine	87-52-5	174.25	C₁₁H₁₄N₂
CFN91165	Bufotenine	487-93-4	204.3	C₁₂H₁₆N₂O
CFN91166	Cinobufotenine	60657-23-0	219.3	C₁₃H₁₉N₂O
CFN90037	Melatonin	73-31-4	232.28	C₁₃H₁₆N₂O₂
CFN90202	Abrine	526-31-8; 21339-55-9	218.25	C₁₂H₁₄N₂O₂
CFN90634	Hypaphorine	487-58-1	246.3	C₁₄H₁₈N₂O₂