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    Natural Products
    Arnicolide C
    Arnicolide C
    Information
    CAS No. 34532-67-7 Price $288 / 5mg
    Catalog No.CFN91996Purity>=98%
    Molecular Weight334.41Type of CompoundSesquiterpenoids
    FormulaC19H26O5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $244.8 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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    Arnicolide C

    Arnicolide C
    Product Name Arnicolide C
    CAS No.: 34532-67-7
    Catalog No.: CFN91996
    Molecular Formula: C19H26O5
    Molecular Weight: 334.41 g/mol
    Purity: >=98%
    Type of Compound: Sesquiterpenoids
    Physical Desc.: Powder
    Source: The herbs of Centipeda minima
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $288 / 5mg
    Inquire / Order: manager@chemfaces.com
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  • J Drug Target.2016, 24:1-28
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Sesquiterpenoids Compound Library
  • Biological Activity
    Description: Arnicolide C exhibits significant antiallergy activity.
    In vitro:
    Chemical & Pharmaceutical Bulletin, 1985, 33(9):4091.
    Biologically active constituents of Centipeda minima: Isolation of a new plenolin ester and the antiallergy activity of sesquiterpene lactones[Reference: WebLink]
    Two pseudoguianolide sesquiterpenes were isolated as antiallergic constituents of Centipeda minima, which has been used as a folk medicine in southeast Asia.
    METHODS AND RESULTS:
    One of the sesquiterpenes, 6-O-senesioylplenolin (2), is a new pseudoguaianolide sesquiterpene lactone, which was isolated along with known pseudoguaianolide, Arnicolide C (1). The two sesquiterpenes exhibited significant antiallergy activity in passive cutaneous anaphylaxis (PCA) tests. An amide isolated along with the sesquiterpenes was identified as aurantiamide acetate (3).
    CONCLUSIONS:
    Three flavonoids obtained from this plant also showed significant antiallergy activity.
    Arnicolide C Description
    Source: The herbs of Centipeda minima
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.9903 mL 14.9517 mL 29.9034 mL 59.8068 mL 74.7585 mL
    5 mM 0.5981 mL 2.9903 mL 5.9807 mL 11.9614 mL 14.9517 mL
    10 mM 0.299 mL 1.4952 mL 2.9903 mL 5.9807 mL 7.4759 mL
    50 mM 0.0598 mL 0.299 mL 0.5981 mL 1.1961 mL 1.4952 mL
    100 mM 0.0299 mL 0.1495 mL 0.299 mL 0.5981 mL 0.7476 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhongguo Zhong Yao Za Zhi. 2009 Jun;34(12):1520-2.
    Chemical constituents from Centipeda minima.[Pubmed: 19777837]
    To study the chemical constituents from Centipeda minima.
    METHODS AND RESULTS:
    The constituents were isolated by column chromatography on silica gel, Sephadex LH-20 and HPLC-ODS, and identified by spectroscopic methods.Ten compounds, (-)-cis-chrysanthenol-O-beta-D-glucopyranoside (1), methy 3,5-dicaffeoylquinate (2), 3,5-di-O-caffeoyl quinicacid (3), tricin (4), 2-amino-4-methyl-pentanoicacid (5), 2-amino-3-phenyl-propionic acid (6), 4-amino-4-carboxychroman-2-one (7), brevilin-A (8), Arnicolide C (9), arnicolide D (10) were isolated and identified.
    CONCLUSIONS:
    Compounds 1-7 were isolated from the plant for the first time.
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    >