Azadirachtin | CAS:11141-17-6 | Manufacturer ChemFaces

Azadirachtin

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Description:

Azadirachtin has antifungal activity, it used as insecticides.

Targets:

Antifection

In vitro:

Annu Rev Entomol. 2019 Oct 8.

Botanical Insecticides in the Twenty-First Century-Fulfilling Their Promise?[Pubmed: 31594414]

METHODS AND RESULTS:
Academic interest in plant natural products with insecticidal properties has continued to grow in the past 20 years, while commercialization of new botanical insecticides and market expansion of existing botanicals has lagged considerably behind. Insecticides based on pyrethrum and neem (Azadirachtin) continue to be standard bearers in this class of pesticides, but globally, their increased presence is largely a consequence of introduction into new jurisdictions. Insecticides based on plant essential oils are just beginning to emerge as useful plant protectants. Some countries (such as Turkey, Uruguay, the United Arab Emirates, and Australia) have relaxed regulatory requirements for specific plant extracts and oils, while in North America and the European Union, stricter requirements have slowed progress toward commercialization of new products.
CONCLUSIONS:
Botanicals are likely to remain niche products in many agricultural regions and may have the greatest impact in developing countries in tropical regions where the source plants are readily available and conventional products are both expensive and dangerous to users.

Toxins (Basel). 2019 Oct 5;11(10). pii: E579.

In Vitro Activity of Neem (Azadirachta indica) Oil on Growth and Ochratoxin A Production by Aspergillus carbonarius Isolates.[Pubmed: 31590398]

Aspergillus carbonarius is a saprobic filamentous fungus, food spoiling fungus and a producer of ochratoxin A (OTA) mycotoxin.
METHODS AND RESULTS:
In this study, the in vitro antifungal activity of neem oil (0.12% p/p of Azadirachtin) was evaluated against the growth of six strains of A. carbonarius and the production of OTA. Four different concentrations of neem oil were tested in addition to three incubation times. Only the concentration of 0.3% of neem oil inhibited more than 95% of the strain's growth (97.6% ± 0.5%), while the use of 0.5% and 1.0% of neem oil showed lower antifungal activity, 40.2% ± 3.1 and 64.7% ± 1.1, respectively. There was a complete inhibition of OTA production with 0.1% and 0.3% neem oil in the four strains isolated in the laboratory from grapes.
CONCLUSIONS:
The present study shows that neem essential oil can be further evaluated as an auxiliary method for the reduction of mycelial growth and OTA production.

Azadirachtin Description

Source:	The barks of Azadirachta Indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Product Name	Azadirachtin
Price:
CAS No.:	11141-17-6
Catalog No.:	CFN91084
Molecular Formula:	C₃₅H₄₄O₁₆
Molecular Weight:	720.72 g/mol
Purity:	>=98%
Type of Compound:	Triterpenoids
Physical Desc.:	Powder
Source:	The barks of Azadirachta Indica
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS
Similar structural:	Comparison
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Triterpenoids Compound Library Antifection Inhibitor Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	1.3875 mL	6.9375 mL	13.875 mL	27.75 mL	34.6875 mL
5 mM	0.2775 mL	1.3875 mL	2.775 mL	5.55 mL	6.9375 mL
10 mM	0.1388 mL	0.6938 mL	1.3875 mL	2.775 mL	3.4688 mL
50 mM	0.0278 mL	0.1388 mL	0.2775 mL	0.555 mL	0.6938 mL
100 mM	0.0139 mL	0.0694 mL	0.1388 mL	0.2775 mL	0.3469 mL

CFN70413	4',5,7-Trihydroxy 3,6,8-trimethoxyflavone	57393-71-2	360.3	C₁₈H₁₆O₈
CFN95145	Rhamnocitrin 3-apiosyl-(1->2)-glucoside	148031-68-9	594.5	C₂₇H₃₀O₁₅
CFN90145	Diacerein	13739-02-1	368.29	C₁₉H₁₂O₈
CFN00010	AAL Toxin TE2	176590-38-8	531.68	C₂₇H₄₉NO₉