Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Dihydroperaksine
    Information
    CAS No. 16100-84-8 Price
    Catalog No.CFN99677Purity>=98%
    Molecular Weight312.4 Type of CompoundAlkaloids
    FormulaC19H24N2O2Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Gyeongsang National University (Korea)
  • Srinakharinwirot University (Thailand)
  • Celltrion Chemical Research Ins... (Korea)
  • Leibniz-Institut für Pflanzenb... (Germany)
  • Medical University of South Car... (USA)
  • Florida A&M University (USA)
  • Yale University (USA)
  • Universidad de Buenos Aires (Argentina)
  • China Medical University (Taiwan)
  • VIB Department of Plant Systems... (Belgium)
  • Istanbul University (Turkey)
  • More...
  • Package
    Featured Products
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $413/5mg
    (-)-Pinoresinol

    Catalog No: CFN92287
    CAS No: 81446-29-9
    Price: $268/5mg
    Ginsenoside Rg6

    Catalog No: CFN90565
    CAS No: 147419-93-0
    Price: $318/5mg
    Leachianone A

    Catalog No: CFN97560
    CAS No: 97938-31-3
    Price: $218/5mg
    Pd-C-II

    Catalog No: CFN95003
    CAS No: N/A
    Price: $358/5mg
    Sikokianin A

    Catalog No: CFN92155
    CAS No: 106293-99-6
    Price: $433/5mg
    alpha-Amyrin

    Catalog No: CFN92377
    CAS No: 638-95-9
    Price: $318/5mg

    Dihydroperaksine

    Dihydroperaksine
    Product Name Dihydroperaksine
    CAS No.: 16100-84-8
    Catalog No.: CFN99677
    Molecular Formula: C19H24N2O2
    Molecular Weight: 312.4 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The herbs of Rauvolfia verticillata
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Plants (Basel).2020, 9(11):1555.
  • PLoS One.2018, 13(3):e0193386
  • Phytomedicine.2020, 79, 153351
  • Cell Rep.2020, 32(11):108158.
  • Org Biomol Chem.2017, 15(31):6483-6492
  • Chem Biol Interact.2019, 315:108910
  • J Sep Sci.2018, 41(9):1938-1946
  • JABS2020, 14:2(2020)
  • Exp Mol Med.2020, 52(4):629-642.
  • Sci Rep. 2017, 12953(7)
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Biological Activity
    Description: Reference standards.
    Dihydroperaksine Description
    Source: The herbs of Rauvolfia verticillata
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Randaiol

    Catalog No: CFN96098
    CAS No: 87562-14-9
    Price: $333/5mg
    Isopsoralenoside

    Catalog No: CFN92225
    CAS No: 905954-18-9
    Price: $338/5mg
    ent-16beta,17-dihydroxy-9(11)-kaur...

    Catalog No: CFN95172
    CAS No: 55483-24-4
    Price: $318/10mg
    Clemastanin B

    Catalog No: CFN95064
    CAS No: 112747-98-5
    Price: $298/10mg
    Shancigusin I

    Catalog No: CFN95061
    CAS No: 1435488-35-9
    Price: $168/5mg
    Bryonamide A

    Catalog No: CFN91056
    CAS No: 75268-14-3
    Price: $268/5mg
    2''-O-Rhamnosylicariside II

    Catalog No: CFN92551
    CAS No: 135293-13-9
    Price: $238/5mg
    Sagittatoside A

    Catalog No: CFN90139
    CAS No: 118525-35-2
    Price: $318/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.201 mL 16.0051 mL 32.0102 mL 64.0205 mL 80.0256 mL
    5 mM 0.6402 mL 3.201 mL 6.402 mL 12.8041 mL 16.0051 mL
    10 mM 0.3201 mL 1.6005 mL 3.201 mL 6.402 mL 8.0026 mL
    50 mM 0.064 mL 0.3201 mL 0.6402 mL 1.2804 mL 1.6005 mL
    100 mM 0.032 mL 0.1601 mL 0.3201 mL 0.6402 mL 0.8003 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Org Chem. 2014 Nov 7;79(21):10030-48.
    General strategy for synthesis of C-19 methyl-substituted sarpagine/macroline/ajmaline indole alkaloids including total synthesis of 19(S),20(R)-dihydroperaksine, 19(S),20(R)-dihydroperaksine-17-al, and peraksine.[Pubmed: 25247616]

    METHODS AND RESULTS:
    A detailed account of the development of a general strategy for synthesis of the C-19 methyl-substituted alkaloids including total synthesis of 19(S),20(R)-Dihydroperaksine-17-al (1), 19(S),20(R)-Dihydroperaksine (2), and peraksine (6) is presented. Efforts directed toward the total synthesis of macrosalhine chloride (5) are also reported. Important to success is the sequence of chemical reactions which include a critical haloboration reaction, regioselective hydroboration, and controlled oxidation (to provide sensitive enolizable aldehydes at C-20). In addition, the all-important Pd-catalyzed α-vinylation reaction has been extended to a chiral C-19 alkyl-substituted substrate for the first time.
    CONCLUSIONS:
    Synthesis of the advanced intermediate 64 completes an improved formal total synthesis of talcarpine (26) and provides a starting point for synthesis of macroline-related alkaloids 27-31. Similarly, extension of this synthetic strategy in the ring A oxygenated series should provide easy access to the northern hemisphere 32b of the bisindoles angustricraline, alstocraline, and foliacraline (Figure 4 ).
    Org Lett. 2011 Oct 7;13(19):5216-9.
    Regiospecific, enantiospecific total synthesis of C-19 methyl substituted sarpagine alkaloids dihydroperaksine-17-al and dihydroperaksine.[Pubmed: 21877687]

    METHODS AND RESULTS:
    The optically active tetracyclic ketone 8 was converted into the pentacylic core 14 of the C-19 methyl substituted N(a)-H sarpagine and ajmaline alkaloids via a critical haloboration reaction. The ketone 14 was then employed in the total synthesis of 19(S),20(R)-Dihydroperaksine-17-al (1) and 19(S),20(R)-Dihydroperaksine (2).
    CONCLUSIONS:
    The key regioselective hydroboration and controlled oxidation-epimerization sequence developed in this approach should provide a general method to functionalize the C(20)-C(21) double bond in the ajmaline-related indole alkaloids.
    Ganoderic acid DM

    Catalog No: CFN99815
    CAS No: 173075-45-1
    Price: $413/5mg
    (-)-Pinoresinol

    Catalog No: CFN92287
    CAS No: 81446-29-9
    Price: $268/5mg
    Ginsenoside Rg6

    Catalog No: CFN90565
    CAS No: 147419-93-0
    Price: $318/5mg
    Leachianone A

    Catalog No: CFN97560
    CAS No: 97938-31-3
    Price: $218/5mg
    Pd-C-II

    Catalog No: CFN95003
    CAS No: N/A
    Price: $358/5mg
    Sikokianin A

    Catalog No: CFN92155
    CAS No: 106293-99-6
    Price: $433/5mg
    alpha-Amyrin

    Catalog No: CFN92377
    CAS No: 638-95-9
    Price: $318/5mg