Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Effusol
    Information
    CAS No. 73166-28-6 Price $238 / 10mg
    Catalog No.CFN90815Purity>=98%
    Molecular Weight252.3Type of CompoundPhenols
    FormulaC17H16O2Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $99.2 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Max Rubner-Institut (MRI) (Germany)
  • Auburn University (USA)
  • Institute of Bioorganic Chemist... (Poland)
  • University of Otago (New Zealand)
  • Kyung Hee University (Korea)
  • Centrum Menselijke Erfelijkheid (Belgium)
  • Universidad Industrial de Santa... (Colombia)
  • Florida A&M University (USA)
  • Biotech R&D Institute (USA)
  • The Ohio State University (USA)
  • University of Hertfordshire (United Kingdom)
  • More...
  • Package
    Featured Products
    Cyanidin-3-O-glucoside chloride

    Catalog No: CFN99740
    CAS No: 7084-24-4
    Price: $118/20mg
    Terrestrosin K

    Catalog No: CFN90822
    CAS No: 193605-07-1
    Price: $218/10mg
    Picroside III

    Catalog No: CFN99567
    CAS No: 64461-95-6
    Price: $228/20mg
    20-Deoxocarnosol

    Catalog No: CFN92175
    CAS No: 94529-97-2
    Price: $463/5mg
    Pyrocurzerenone

    Catalog No: CFN96169
    CAS No: 20013-75-6
    Price: $388/20mg
    3,5-Di-O-caffeoylquinic acid methy...

    Catalog No: CFN90857
    CAS No: 159934-13-1
    Price: $388/5mg
    3,6'-Disinapoyl sucrose

    Catalog No: CFN90578
    CAS No: 139891-98-8
    Price: $90/20mg

    Effusol

    Effusol
    Product Name Effusol
    CAS No.: 73166-28-6
    Catalog No.: CFN90815
    Molecular Formula: C17H16O2
    Molecular Weight: 252.3 g/mol
    Purity: >=98%
    Type of Compound: Phenols
    Physical Desc.: Powder
    Targets: Caspase
    Source: The stem of Juncus effusus L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $238 / 10mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Phytomedicine.2021, 84:153501.
  • J Chromatogr Sci.2020, 58(6):485-493.
  • Bio-protocol2018, 9(14):e3301
  • J Microbiol Immunol Infect.2021, S1684-1182(21)00142-0.
  • Biochem Pharmacol.2020, 178:114083
  • Biol Pharm Bull.2020, 43(10):1534-1541.
  • Front Plant Sci.2020, 11:630.
  • J Agric Food Chem.2021, 69(11):3496-3510.
  • Phytochem Anal.2013, 24(5):493-503
  • J Nat Med.2020, 74(1):65-75
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cytotoxic Compound Library
  • Phenols Compound Library
  • Caspase Inhibitor Library
  • Biological Activity
    Description: Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells.
    Targets: Caspase
    In vitro:
    J Nat Med. 2015 Jul;69(3):421-6.
    Chemical constituents isolated from Juncus effusus induce cytotoxicity in HT22 cells.[Pubmed: 25794817 ]
    Effususol A (1), a new 9,10-dihydrophenanthrene, has been isolated from the medullae of Juncus effusus along with ten known compounds, Effusol (2), dehydroEffusol (3), juncusol (4), dehydrojuncusol (5), juncuenin B (6), dehydrojuncuenin B (7), juncuenin D (8), luteolin (9), luteolin 5-methyl ether (10), and 4-hydroxy-2,3-dimethyl-2-nonen-4-olide (11).
    METHODS AND RESULTS:
    The structure of 1 was elucidated on the basis of spectroscopic data. 2, 4, 6, 7, and 8 have induced caspase-3-mediated cytotoxicity in HT22 cells.
    In vivo:
    Nat Prod Commun. 2014 Aug;9(8):1177-8.
    Two new anxiolytic phenanthrenes found in the medullae of Juncus effusus.[Pubmed: 25233602]
    Six phenanthrenes, 2-methoxy-7-hydroxy-1-methyl-5-vinyl phenanthrene (1), juncusin (2), dehydroEffusol (3), juncusol (4), Effusol (5), and dehydroeffusal (6), were isolated from the medullae of Juncus effusus L.
    METHODS AND RESULTS:
    Compounds 1 and 2 were identified as being new structures, and both of them showed anxiolytic activity at dosages of 10 and 2.5 mg/kg, respectively.
    Effusol Description
    Source: The stem of Juncus effusus L.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Fuzitine

    Catalog No: CFN95337
    CAS No: 142287-96-5
    Price: $318/5mg
    Isoengeletin

    Catalog No: CFN95284
    CAS No: 30987-58-7
    Price: $318/5mg
    Suchilactone

    Catalog No: CFN95010
    CAS No: 50816-74-5
    Price: $338/5mg
    Hydroxytyrosol 1-O-glucoside

    Catalog No: CFN95367
    CAS No: 76873-99-9
    Price: $318/10mg
    New compound 9

    Catalog No: CFN95342
    CAS No: N/A
    Price: $413/5mg
    7-O-(4-beta-D-glucopyranosyloxy-3-...

    Catalog No: CFN95365
    CAS No: 469899-55-6
    Price: $368/5mg
    1-Methoxycarbonyl-beta-carboline-N...

    Catalog No: CFN95023
    CAS No: 74690-74-7
    Price: $318/5mg
    Parvisoflavanone

    Catalog No: CFN95077
    CAS No: 49776-79-6
    Price: $413/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.9635 mL 19.8177 mL 39.6354 mL 79.2707 mL 99.0884 mL
    5 mM 0.7927 mL 3.9635 mL 7.9271 mL 15.8541 mL 19.8177 mL
    10 mM 0.3964 mL 1.9818 mL 3.9635 mL 7.9271 mL 9.9088 mL
    50 mM 0.0793 mL 0.3964 mL 0.7927 mL 1.5854 mL 1.9818 mL
    100 mM 0.0396 mL 0.1982 mL 0.3964 mL 0.7927 mL 0.9909 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Cyanidin-3-O-glucoside chloride

    Catalog No: CFN99740
    CAS No: 7084-24-4
    Price: $118/20mg
    Terrestrosin K

    Catalog No: CFN90822
    CAS No: 193605-07-1
    Price: $218/10mg
    Picroside III

    Catalog No: CFN99567
    CAS No: 64461-95-6
    Price: $228/20mg
    20-Deoxocarnosol

    Catalog No: CFN92175
    CAS No: 94529-97-2
    Price: $463/5mg
    Pyrocurzerenone

    Catalog No: CFN96169
    CAS No: 20013-75-6
    Price: $388/20mg
    3,5-Di-O-caffeoylquinic acid methy...

    Catalog No: CFN90857
    CAS No: 159934-13-1
    Price: $388/5mg
    3,6'-Disinapoyl sucrose

    Catalog No: CFN90578
    CAS No: 139891-98-8
    Price: $90/20mg