ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
3. Inhibitors
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: info@chemfaces.com
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Tel: (0086)-27-84237683
Fax: (0086)-27-84254680
E-mail: manager@chemfaces.com
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery time
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2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / $99.2 / In-stock |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
More articles cited ChemFaces products.
J Appl Biol Chem2021, 64(3):245-251.Front Pharmacol.2020, 11:566490.BMC Complement Med Ther. ...2020...Chem Pharm Bull (Tokyo)....2019...Biomed Pharmacother.2022, 146:112497.Internoational J of Toxicology...2020...Antioxidants (Basel).2021, 10(1):112. Research on Crops.2017, 18(2)
Oncotarget.2017, 8(64):108006-108019Toxicol Res.2019, 35(4):371-387Molecules.2018, 23(7):E1659Int J Oncol.2019, 55(1):320-330FEBS Lett.2015, 589(1):182-7Saudi Pharm J2020, 10.1016J Ethnopharmacol.2022, 282:114574. Tokyo Pharmaceutical University...2020...
Front Aging Neurosci.2019, 11:230Plant Sci.2020, 301:110656.J Cell Mol Med.2018, 22(9):4236-4242Journal of Ginseng Research...2021...Agriculture2022, 12(2),227.Phytomedicine.2015, 22(11):1027-36Mol Med Rep.2014, 9(5):1653-9
More...
Our products had been exported to the following research institutions and universities, And still growing.
Max Rubner-Institut (MRI) (Germany)Auburn University (USA)Institute of Bioorganic Chemist... (Poland)University of Otago (New Zealand)
Kyung Hee University (Korea)Centrum Menselijke Erfelijkheid (Belgium)Universidad Industrial de Santa... (Colombia)Florida A&M University (USA)
Biotech R&D Institute (USA)The Ohio State University (USA)University of Hertfordshire (United Kingdom)
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Effusol
Inquire / Order:
manager@chemfaces.com
Technical Inquiries:
service@chemfaces.com
Tel:
+86-27-84237783
Fax:
+86-27-84254680
Address:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Phytomedicine.2021, 84:153501. J Chromatogr Sci.2020, 58(6):485-493.Bio-protocol2018, 9(14):e3301J Microbiol Immunol Infect.2021, S1684-1182(21)00142-0. Biochem Pharmacol.2020, 178:114083Biol Pharm Bull.2020, 43(10):1534-1541.Front Plant Sci.2020, 11:630.J Agric Food Chem.2021, 69(11):3496-3510. Phytochem Anal.2013, 24(5):493-503J Nat Med.2020, 74(1):65-75
Related Screening Libraries
| Description: |
Effusol can induce caspase-3-mediated cytotoxicity in HT22 cells. |
| Targets: |
Caspase |
| In vitro: |
| J Nat Med. 2015 Jul;69(3):421-6. | | Chemical constituents isolated from Juncus effusus induce cytotoxicity in HT22 cells.[Pubmed: 25794817 ] | Effususol A (1), a new 9,10-dihydrophenanthrene, has been isolated from the medullae of Juncus effusus along with ten known compounds, Effusol (2), dehydroEffusol (3), juncusol (4), dehydrojuncusol (5), juncuenin B (6), dehydrojuncuenin B (7), juncuenin D (8), luteolin (9), luteolin 5-methyl ether (10), and 4-hydroxy-2,3-dimethyl-2-nonen-4-olide (11).
METHODS AND RESULTS:
The structure of 1 was elucidated on the basis of spectroscopic data. 2, 4, 6, 7, and 8 have induced caspase-3-mediated cytotoxicity in HT22 cells. |
|
| In vivo: |
| Nat Prod Commun. 2014 Aug;9(8):1177-8. | | Two new anxiolytic phenanthrenes found in the medullae of Juncus effusus.[Pubmed: 25233602] | Six phenanthrenes, 2-methoxy-7-hydroxy-1-methyl-5-vinyl phenanthrene (1), juncusin (2), dehydroEffusol (3), juncusol (4), Effusol (5), and dehydroeffusal (6), were isolated from the medullae of Juncus effusus L.
METHODS AND RESULTS:
Compounds 1 and 2 were identified as being new structures, and both of them showed anxiolytic activity at dosages of 10 and 2.5 mg/kg, respectively. |
|
Effusol Description
| Source: |
The stem of Juncus effusus L. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.9635 mL |
19.8177 mL |
39.6354 mL |
79.2707 mL |
99.0884 mL |
| 5 mM |
0.7927 mL |
3.9635 mL |
7.9271 mL |
15.8541 mL |
19.8177 mL |
| 10 mM |
0.3964 mL |
1.9818 mL |
3.9635 mL |
7.9271 mL |
9.9088 mL |
| 50 mM |
0.0793 mL |
0.3964 mL |
0.7927 mL |
1.5854 mL |
1.9818 mL |
| 100 mM |
0.0396 mL |
0.1982 mL |
0.3964 mL |
0.7927 mL |
0.9909 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
