ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: email@example.com
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $400.2 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Arch Pharm Res.2015, 38(6):1080-9Semyung University2017, 149407Molecules.2017, 22(3)Srinagarind Medical Journal2017, 32(1)Biochem Biophys Res Commun....2017...LWT-Food Science and Technology...2017...Asian J of Pharmaceutical&Clinica...2018...Int J Mol Sci.2018, 19(2)
Sci Rep.2018, 8:9267Front Pharmacol.2019, 10:1355Nutr Res Pract2019, 13:e45Neuropharmacology2019, 151437Genes Genomics.2020, 10.1007Plant Foods Hum Nutr.2020, 10.1007Nutrients2020, 12(2):488Neurochem Int.2020, 133:104629
Int J Pharmacol2020, 16:1-9Nutrients.2020, 12(3):595.BMC Plant Biol.2020, 20(1):214. J Biochem Mol Toxicol....2020...Korean Herb. Med. Inf....2020...Biorxiv.2020, doi: 10.1101.Natural Product Communications...2020...
Our products had been exported to the following research institutions and universities, And still growing.
Universita' Degli Studi Di Cagl... (Italy)Julius Kühn-Institut (Germany)Harvard University (USA)Universidad de Buenos Aires (Argentina)
Universidad Miguel Hernández (Spain)Max-Planck-Insitut (Germany)Uniwersytet Gdański (Poland)Institute of Pathophysiology Me... (Austria)
University of Helsinki (Finland)University of Maryland (USA)Yale University (USA)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Proc Natl Acad Sci USA.2016, 113(30):E4407-1Integr Cancer Ther.2018, 17(3):832-843Nutrients.2019, 11(4):E936Food Chem.2017, 221:1135-1144Int J Biol Macromol.2018, 112:1093-1103Biomed Sci Letters.2020, 26:319-326Mol Med Rep.2015, 12(5):7789-95Food Chem.2020, 332:127412Br J Pharmacol.2018, 175(6):902-923Korean Journal of Pharmacognosy2018, 49(3):270-277
Related Screening Libraries
||Herpetone exhibits protective effects on CCl(4)-induced hepatocyte injury, it shows anti-hepatitis B virus (HBV) activity. |
|Molecules. 2016 Dec 27;22(1). pii: E14. |
|Anti-HBV Activities of Three Compounds Extracted and Purified from Herpetospermum Seeds.[Pubmed: 28035986 ]|
|The goal of this research was to evaluate the anti-hepatitis B virus (HBV) activities of three compounds extracted and purified from Herpetospermum seeds (HS) on HepG2.2.15 cells.
METHODS AND RESULTS:
Herpetin (HPT), Herpetone (HPO), and herpetfluorenone (HPF) were isolated from HS and identified using HR-ESI-MS and NMR. Different concentrations of the drugs were added to the HepG2.2.15 cells. Cell toxicity was observed with an MTT assay, cell culture supernatants were collected, and HBsAg and HBeAg were detected by ELISA. The content of HBV DNA was determined via quantitative polymerase chain reaction (PCR) with fluorescent probes.
The 50% toxicity concentration (TC50) of HPF was 531.48 μg/mL, suggesting that this species is less toxic than HPT and HPO.
HPT and HPF showed more potent antiviral activities than HPO. The 50% inhibition concentration (IC50) values of HPF on HBsAg and HBeAg were 176.99 and 134.53 μg/mL, respectively, and the corresponding therapeutic index (TI) values were 2.66 and 3.49, respectively. HPT and HPF were shown to significantly reduce the level of HBV DNA in the HepG2.2.15 culture medium compared to the negative control. This initial investigation of the anti-HBV constituents of HS yielded three compounds that revealed a synergistic effect of multiple components in the ethnopharmacological use of HS.
||The fruits of Herpetospermum pedunculosum
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Chem Pharm Bull (Tokyo). 2008 Feb;56(2):192-3. |
|Two new coumarins from Herpetospermum caudigerum.[Pubmed: 18239307]|
METHODS AND RESULTS:
The ethyl acetate extract from the seeds of Herpetospermum caudigerum was found to show protective effects on carbon tetrachloride (CCl(4)) and thioacetamide (TAA)-induced acute hepatic injuries in mice. From the ethyl acetate extract, two new coumarins, herpetolide A (1) and herpetolide B (2), along with four known compounds, Herpetone (3), dehydrodiconiferyl alcohol (4), 2,4-dihydroxypyrimidine (5) and stigmasterol (6) were isolated.
The structures of the new coumarins were elucidated on the basis of chemical and physicochemical evidences. Herpetone exhibited protective effects on CCl(4)-induced hepatocyte injury.