ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: firstname.lastname@example.org
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $7.0 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules.2017, 22(6)J of L. Chroma.&Related Tech...2017...Sci Rep.2021, 11(1):10931.Appl. Sci.2020, 10(4),1304Planta Med.2019, 85(4):347-355Korean Herb. Med. Inf....2020...Braz J Med Biol Res....2021...Biol Pharm Bull.2018, 41(11):1645-1651
Molecules.2021, 26(4):1084.Molecules.2017, 22(2)Pharmaceutics2022, 14(2),376.PLoS One.2018, 13(3):e0193386Biochem Biophys Res Commun....2018...The Japan Society for Analytical ...2018...Front Pharmacol.2017, 8:205Pharmacognosy Magazine...2017...
Tea Res. Ins. Of China2017, 1-12Korean J Pain.2021, 34(4):405-416.Biochem Biophys Res Commun....2020...Anticancer Res.2021, 41(3):1357-1364.Molecules.2021, 26(6):1738. Nat Prod Communications2018, 10.1177J Int Med Res....2021...
Our products had been exported to the following research institutions and universities, And still growing.
Massachusetts General Hospital (USA)Imperial College London (United Kingdom)Universidad de Antioquia (Colombia)Texas A&M University (USA)
Heinrich-Heine-University Düss... (Germany)University of Toronto (Canada)Max Rubner-Institut (MRI) (Germany)University of Malaya (Malaysia)
Seoul National University of Sc... (Korea)The Australian National University (Australia)Ateneo de Manila University (Philippines)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
J Ethnopharmacol.2019, 228:132-141Tumour Biol.2015, 36(9):7027-34Exp Biol Med (Maywood).2019, 244(18):1665-1679Phytomedicine.2016, 23(4):331-9Bioorg Med Chem.2020, 28(12):115553.Process Biochemistry2019, 85:106-115Phytochem Anal.2013, 24(5):493-503LWT2021, 138:110397.Foods.2021, 10(11):2754.J Cancer.2019, 10(23):5843-5851
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Miscellaneous Compound Library
|| Hexanoic acid is a potent natural priming agent of proven efficiency in a wide range of host plants and pathogens. It can early activate broad-spectrum defenses by inducing callose deposition and the salicylic acid (SA) and jasmonic acid (JA) pathways。|
|Frontiers in Plant ence, 2014, 5(488):488. |
|Priming of plant resistance by natural compounds. Hexanoic acid as a model.[Pubmed: 25324848]|
|Some alternative control strategies of currently emerging plant diseases are based on the use of resistance inducers. This review highlights the recent advances made in the characterization of natural compounds that induce resistance by a priming mechanism. These include vitamins, chitosans, oligogalacturonides, volatile organic compounds, azelaic and pipecolic acid, among others. Overall, other than providing novel disease control strategies that meet environmental regulations, natural priming agents are valuable tools to help unravel the complex mechanisms underlying the induced resistance (IR) phenomenon.
METHODS AND RESULTS:
The data presented in this review reflect the novel contributions made from studying these natural plant inducers, with special emphasis placed on Hexanoic acid (Hx), proposed herein as a model tool for this research field. Hx is a potent natural priming agent of proven efficiency in a wide range of host plants and pathogens. It can early activate broad-spectrum defenses by inducing callose deposition and the salicylic acid (SA) and jasmonic acid (JA) pathways. Later it can prime pathogen-specific responses according to the pathogen’s lifestyle. Interestingly, Hx primes redox-related genes to produce an anti-oxidant protective effect, which might be critical for limiting the infection of necrotrophs.
Our Hx-IR findings also strongly suggest that it is an attractive tool for the molecular characterization of the plant alarmed state, with the added advantage of it being a natural compound.
|J Plant Physiol,2011 Mar 1;168(4):359-66. |
|Priming for JA-dependent defenses using hexanoic acid is an effective mechanism to protect Arabidopsis against B. cinerea.[Pubmed: 20950893]|
METHODS AND RESULTS:
Soil drench treatments with Hexanoic acid can effectively protect Arabidopsis plants against Botrytis cinerea through a mechanism based on a stronger and faster accumulation of JA-dependent defenses. Plants impaired in ethylene, salicylic acid, abscisic acid or glutathion pathways showed intact protection by Hexanoic acid upon B. cinerea infection. Accordingly, no significant changes in the SA marker gene PR-1 in either the SA or ABA hormone balance were observed in the infected and treated plants. In contrast, the JA signaling pathway showed dramatic changes after Hexanoic acid treatment, mainly when the pathogen was present. The impaired JA mutants, jin1-2 and jar1, were unable to display Hexanoic acid priming against the necrotroph. In addition, Hexanoic acid-treated plants infected with B. cinerea showed priming in the expression of the PDF1.2, PR-4 and VSP1 genes implicated in the JA pathways. Moreover, JA and OPDA levels were primed at early stages by Hexanoic acid. Treatments also stimulated increased callose accumulation in response to the pathogen. Although callose accumulation has proved an effective IR mechanism against B. cinerea, it is apparently not essential to express Hexanoic acid-induced resistance (HxAc-IR) because the mutant pmr4.1 (callose synthesis defective mutant) is protected by treatment.
We recently described how Hexanoic acid treatments can protect tomato plants against B. cinerea by stimulating ABA-dependent callose deposition and by priming OPDA and JA-Ile production.
We clearly demonstrate here that Hx-IR is a dependent plant species, since this acid protects Arabidopsis plants against the same necrotroph by priming JA-dependent defenses without enhancing callose accumulation.
Hexanoic acid Description
||The fruits of Apple
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: email@example.com
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.