ChemFaces is a professional high-purity natural products manufacturer.
Product Intended Use
1. Reference standards
2. Pharmacological research
Citing Use of our Products
How to Order
Orders via your E-mail:
1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Sent to Email: email@example.com
Order & Inquiry & Tech Support
Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
Delivery & Payment method
1. Usually delivery time: Next day delivery by 9:00 a.m. Order now
2. We accept: Wire transfer & Credit card & Paypal & Western Union
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $58.6 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Molecules. 2013, 18(11):14105-21Molecules.2015, 20(11):20014-30Oncotarget.2015, 6(31):30831-49Phytomedicine.2016, 23(4):331-9The Japan Society for Analy. Chem...2017...Pharmacol Rep.2017, 69(6):1224-1231Sci Rep.2017, 7:40345Malaysian J of Fundamental and Ap...2018...
Molecules.2018, 23(12):E3103J of Health Science and Alternati...2019...Saf Health Work.2019, 10(2):196-204Molecules.2019, 24(19):E3417Med Sci Monit.2019, 25:9499-9508Chinese Pharmacological Bulletin...2019...J Food Biochem.2019, 43(9):e12970Chemistry of Natural Compounds...2019...
Int J Oncol.2019, 55(1):320-330Int J Food Sci Nutr.2019, 70(7):825-833Pharmacognosy Journal....2020...J Vet Sci.2020, 21(3):e39.Molecules.2020, 25(20):4851.Molecules.2020, 25(7):1625.Biorxiv.2020, doi: 10.1101.
Our products had been exported to the following research institutions and universities, And still growing.
Chulalongkorn University (Thailand)University of Bonn (Germany)FORTH-IMBB (Greece)Monash University (Australia)
Vin?a Institute of Nuclear Scie... (Serbia)Gyeongsang National University (Korea)Universite Libre de Bruxelles (Belgium)Institute of Chinese Materia Me... (China)
Universidad de La Salle (Mexico)Universidade da Beira Interior (Germany)Chinese University of Hong Kong (China)
Inquire / Order:
1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Chemistry of Plant Materials.2019, 215-222J Pharm Biomed Anal.2017, 140:274-280Int J Mol Sci.2019, 20(16):E4015Postharvest Biol Tec2019, 149:18-26J Exp Bot.2016, 67(12):3777-88Evid Based Complement Alternat Med.2017, 2017:1583185Front Pharmacol.2020, 11:683.Natural Product Communications2020, doi: 10.1177.J Chromatogr A.2017, 1518:46-58Molecules.2020, 25(11):2599.
Related Screening Libraries
||Linderalactone shows hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with the EC(50) value of 98.0 microM. It shows significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB, the IC50 is 8.48 microg/mL.
||Immunology & Inflammation related|
|Nat Prod Res. 2005 Apr;19(3):283-6. |
|Anti-inflammatory furanogermacrane sesquiterpenes from Neolitsea parvigemma.[Pubmed: 15702642]|
METHODS AND RESULTS:
Six furanogermacrane sesquiterpenes, pseudoneolinderane (1), Linderalactone (2), zeylanidine (3), zeylanicine (4), deacetylzeylanidine (5), and neolitrane (6), isolated from the stems of Neolitsea parvigemma, were tested for anti-inflammatory activities.
Among them, 1 and 2 showed significant inhibitory effects on superoxide anion generation by human neutrophils in response to fMLP/CB. The IC50 of 1 and 2 were found to be 3.21 and 8.48 microg/mL, respectively.
||The roots of Lindera aggregata
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|J Nat Prod. 2009 Aug;72(8):1497-501. |
|Sesquiterpene lactones from the root tubers of Lindera aggregata.[Pubmed: 19639966]|
Phytochemical investigation of the root tubers of Lindera aggregata resulted in the isolation of five new sesquiterpene lactones, linderagalactones A-E (1-5), along with eight known sesquiterpenoids, 3-eudesmene-1beta,11-diol, hydroxylindestenolide, strychnistenolide, hydroxyisogermafurenolide, atractylenolide III, linderane, neoLinderalactone, and Linderalactone.
METHODS AND RESULTS:
The structures and relative configurations of 1-5 were determined by spectroscopic methods, especially HRESIMS and 2D NMR techniques. The absolute configurations of 1-4 were defined by comparison of quantum chemical TDDFT calculated and experimental ECD spectra. Linderagalactone A (1) is a halogenated sesquiterpene lactone possessing a unique rearranged carbon skeleton. Linderagalactone E (5), linderane, hydroxylindestenolide, and Linderalactone showed hepatoprotective activity against H2O2-induced oxidative damages on HepG2 cells with EC(50) values of 67.5, 167.0, 42.4, and 98.0 microM, respectively.
|Zhongguo Zhong Yao Za Zhi. 2001 Nov;26(11):765-7. |
|Studies on constituents of the leaves of Lindera aggregata (Sims) Kosterm.[Pubmed: 12776349]|
|To study the antibacterial and anti-inflammatory constituents of the leaves of Lindera aggrega.
METHODS AND RESULTS:
Compounds were isolated by colum chromatography, and the structures were identified by spectroscopic methods.
Six compounds were isolated and identified as mixture of 6-Acetyllindenanolide B-1 and B-2(I), dehydrolindestrenolide (II), hydroxylinderstrenolide (III), Linderalactone (IV), kameofero (V), beta-sitosterol (VI).
These compounds were obtained from the leaves of Lindera aggregata for the first time.