Science | Nature | Cell | View More
Natural Products
Momordicoside F1
Momordicoside F1
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Momordicoside F1
Price:
CAS No.: 81348-81-4
Catalog No.: CFN92306
Molecular Formula: C37H60O8
Molecular Weight: 632.9 g/mol
Purity: >=98%
Type of Compound: Triterpenoids
Physical Desc.: Powder
Source: The herbs of Mormodica charantia L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS    SDF    Manual
Similar structural: Comparison (Web)  (SDF)
Guestbook:
Contact Us
Order & Inquiry & Tech Support

Tel: (0086)-27-84237683
Tech: service@chemfaces.com
Order: manager@chemfaces.com
Address: 176, CheCheng Eest Rd., WETDZ, Wuhan, Hubei 430056, PRC
How to Order
Orders via your E-mail:

1. Product number / Name / CAS No.
2. Delivery address
3. Ordering/billing address
4. Contact information
Order: manager@chemfaces.com
Delivery time
Delivery & Payment method

1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

2. We accept: Wire transfer & Credit card & Paypal
Citing Use of our Products
* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
Our products had been exported to the following research institutions and universities, And still growing.
  • University of Medicine and Phar... (Romania)
  • University of Sao Paulo (Brazil)
  • Uniwersytet Jagielloński w Kra... (Poland)
  • Rio de Janeiro State University (Brazil)
  • Indian Institute of Science (India)
  • The University of Newcastle (Australia)
  • Regional Crop Research Institute (Korea)
  • National Cancer Institute (USA)
  • Amity University (India)
  • University of Pretoria (South Africa)
  • Korea Food Research Institute(K... (Korea)
  • More...
Package
Featured Products
Paclitaxel

Catalog No: CFN97759
CAS No: 33069-62-4
Price: $30/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Soyasaponin Aa

Catalog No: CFN90455
CAS No: 117230-33-8
Price: $ / mg
Cannabidiol

Catalog No: CFN99444
CAS No: 13956-29-1
Price: $40/20mg
Xanthotoxin

Catalog No: CFN98372
CAS No: 298-81-7
Price: $30/20mg
L-Menthol

Catalog No: CFN98123
CAS No: 2216-51-5
Price: $30/20mg
Aloin A

Catalog No: CFN99943
CAS No: 1415-73-2
Price: $30/20mg
Byakangelicol

Catalog No: CFN98167
CAS No: 26091-79-2
Price: $118/20mg
Procyanidin A1

Catalog No: CFN96495
CAS No: 103883-03-0
Price: $288/20mg
4',5,6,7-Tetramethoxyflavone

Catalog No: CFN91034
CAS No: 1168-42-9
Price: $258/5mg
Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Momordicoside F1 may have antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines.
In vitro:
Journal of Agricultural and Food Chemistry, 2013, 61(12):2979-2986.
Antiproliferative and hypoglycemic cucurbitane-type glycosides from the fruits of Momordica charantia.[Pubmed: 23432055 ]

METHODS AND RESULTS:
This paper reports that bioassay-guided fractionations of EtOH extract of Momordica charantia fruits led to the isolation of 15 cucurbitane-type triterpene glycosides including 4 new compounds, kuguaosides A-D (1-4), along with 11 known ones, charantoside A (5), momordicoside I (6), Momordicoside F1 (7), momordicoside F2 (8), momordicoside K (9), momordicoside L (10), and momordicoside U (11), goyaglycosides-b (12) and -d (13), 7β,25-dihydroxycucurbita-5,23(E)-dien-19-al 3-O-β-d-allopyranoside (14), and 25-hydroxy-5β,19-epoxycucurbita-6,23-dien-19-on-3β-ol 3-O-β-d-glucopyranoside (15). Their structures were elucidated on the basis of spectroscopic analyses and chemical methods. This study also established the HPLC-ELSD fingerprinting profile of an antiproliferative fraction of which 11 main peaks were identified.
CONCLUSIONS:
Biological evaluation showed that several isolated cucurbitane-type triterpene glycosides had antiproliferative activities against MCF-7, WiDr, HEp-2, and Doay human tumor cell lines. In addition, compound 14 showed potent hypoglycemic activities by glucose uptake assay.
Momordicoside F1 Description
Source: The herbs of Mormodica charantia L.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
11alpha-hydroxy-3,7-dioxo-5alpha-l...

Catalog No: CFN95592
CAS No: 1245703-70-1
Price: $413/5mg
Leachianol F

Catalog No: CFN95147
CAS No: 164123-50-6
Price: $318/5mg
Dipsacus saponin X

Catalog No: CFN95359
CAS No: 146100-01-8
Price: $318/20mg
Schisphenlignan I

Catalog No: CFN95586
CAS No: 1542234-14-9
Price: $318/5mg
Spinacetin

Catalog No: CFN95194
CAS No: 3153-83-1
Price: $318/5mg
Silychristin B

Catalog No: CFN95160
CAS No: 879325-58-3
Price: $318/5mg
Polygalasaponin XLIX

Catalog No: CFN95117
CAS No: 1033593-12-2
Price: $318/10mg
2''-O-acetylsaikosaponin A

Catalog No: CFN95085
CAS No: 102934-42-9
Price: $318/5mg
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.58 mL 7.9001 mL 15.8003 mL 31.6006 mL 39.5007 mL
5 mM 0.316 mL 1.58 mL 3.1601 mL 6.3201 mL 7.9001 mL
10 mM 0.158 mL 0.79 mL 1.58 mL 3.1601 mL 3.9501 mL
50 mM 0.0316 mL 0.158 mL 0.316 mL 0.632 mL 0.79 mL
100 mM 0.0158 mL 0.079 mL 0.158 mL 0.316 mL 0.395 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
CHEMICAL & PHARMACEUTICAL BULLETIN, 1982, 30(11):3977-3986.
Studies on the Constituents of Momordica charantia L. III. Characterization of New Cucurbitacin Glycosides of the Immature Fruits. (1). Structures of Momordicosides G, F1, F2 and I[Reference: WebLink]

METHODS AND RESULTS:
Several non-bitter cucurbitacin glycosides were isolated together with two bitter cucurbitacin glycosides from the immature fruits of Momordica charantia L. (Cucurbitaceae), and four of the non-bitter glycosides, momordicoside G, Momordicoside F1, momordicoside F2 and momordicoside I, were characterized from chemical and spectral evidence as folows ; G, 3-O-β-D-allopyranoside of 5, 19-epoxy-25-methoxy-5β-cucurbita-6, 23-dien-3β-ol ; F1, 3-O-β-D-glucopyranoside of 5, 19-epoxy-25β-methoxy-5β-cucurbita-6, 23-dien-3β-ol ; F2, 3-O-β-D-allopyranoside of 5, 19-epoxy-5β-cucurbita-6, 23-diene-3β, 25-diol ; I, 3-O-β-D-glucopyranoside of 5, 19-epoxy-5β-cucurbita-6, 23-diene-3β, 25-diol.
Paclitaxel

Catalog No: CFN97759
CAS No: 33069-62-4
Price: $30/20mg
Betulin

Catalog No: CFN98710
CAS No: 473-98-3
Price: $30/20mg
Soyasaponin Aa

Catalog No: CFN90455
CAS No: 117230-33-8
Price: $ / mg
Cannabidiol

Catalog No: CFN99444
CAS No: 13956-29-1
Price: $40/20mg
Xanthotoxin

Catalog No: CFN98372
CAS No: 298-81-7
Price: $30/20mg
L-Menthol

Catalog No: CFN98123
CAS No: 2216-51-5
Price: $30/20mg
Aloin A

Catalog No: CFN99943
CAS No: 1415-73-2
Price: $30/20mg
Byakangelicol

Catalog No: CFN98167
CAS No: 26091-79-2
Price: $118/20mg
Procyanidin A1

Catalog No: CFN96495
CAS No: 103883-03-0
Price: $288/20mg
4',5,6,7-Tetramethoxyflavone

Catalog No: CFN91034
CAS No: 1168-42-9
Price: $258/5mg
Tags: buy Momordicoside F1 | Momordicoside F1 supplier | purchase Momordicoside F1 | Momordicoside F1 cost | Momordicoside F1 manufacturer | order Momordicoside F1 | Momordicoside F1 distributor