Info: Read More
  • Home
  • Natural Products
  • Bioactive
  • Screening Libraries
  • Hot Products
  • Plant Catalog
  • Customer Support
  • Product Use Citation
  • About Us
  • Contact Us
  • How to Order
  • Delivery time
  • Science | Nature | Cell | View More
    Natural Products
    Murraol
    Information
    CAS No. 109741-38-0 Price
    Catalog No.CFN99097Purity>=98%
    Molecular Weight260.3 Type of CompoundCoumarins
    FormulaC15H16O4Physical DescriptionCryst.
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
    Citing Use of our Products
    How to Order
    Orders via your E-mail:

    1. Product number / Name / CAS No.
    2. Delivery address
    3. Ordering/billing address
    4. Contact information
    Sent to Email: info@chemfaces.com
    Contact Us
    Order & Inquiry & Tech Support

    Tel: (0086)-27-84237683
    Fax: (0086)-27-84254680
    E-mail: manager@chemfaces.com
    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
    Delivery time
    Delivery & Payment method

    1. Usually delivery time: Next day delivery by 9:00 a.m. Order now

    2. We accept: Wire transfer & Credit card & Paypal & Western Union
    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
  • Center for protein Engineering ... (Belgium)
  • Auburn University (USA)
  • University of Toulouse (France)
  • Nicolaus Copernicus Uniwersity (Poland)
  • Technical University of Denmark (Denmark)
  • Kazusa DNA Research Institute (Japan)
  • Ain Shams University (Egypt)
  • Universidade Federal de Pernamb... (Brazil)
  • Universidade Católica Portuguesa (Portugal)
  • University of Wisconsin-Madison (USA)
  • Universidad Veracuzana (Mexico)
  • More...
  • Package
    Featured Products
    Morusinol

    Catalog No: CFN97086
    CAS No: 62949-93-3
    Price: $318/5mg
    Isochlorogenic acid C

    Catalog No: CFN99120
    CAS No: 32451-88-0
    Price: $100/20mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $318/5mg
    Sibiricaxanthone B

    Catalog No: CFN90644
    CAS No: 241125-81-5
    Price: $238/20mg
    Decuroside I

    Catalog No: CFN95004
    CAS No: 96638-79-8
    Price: $318/5mg
    Tangeretin

    Catalog No: CFN90240
    CAS No: 481-53-8
    Price: $30/20mg
    2,4'-Dihydroxybenzophenone

    Catalog No: CFN92400
    CAS No: 606-12-2
    Price: $40/20mg

    Murraol

    Murraol
    Product Name Murraol
    CAS No.: 109741-38-0
    Catalog No.: CFN99097
    Molecular Formula: C15H16O4
    Molecular Weight: 260.3 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Cryst.
    Targets: Antifection
    Source: The herbs of Murraya exotica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
    Tel: +86-27-84237783
    Fax: +86-27-84254680

    Address:
    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
  • Molecules.2020, 25(23):5556.
  • Applied Biological Chemistry2022, 65(12)
  • Pharmaceutics.2021, 13(7):1028.
  • Nutrients.2017, 10(1)
  • Nat Commun.2021, 12(1):681.
  • Biochem Biophys Res Commun.2017, 482(4):1095-1101
  • Evid Based Complement Alternat Med.2021, 2021:8850744.
  • Anticancer Res.2018, 38(4):2127-2135
  • Aquaculture2017, 481:94-102
  • Sci Rep.2018, 8:15059
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Pro-osteoblastogenesis Compound Library
  • Coumarins Compound Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: Murraol shows the significant proliferative activities on osteoblast-like UMR106 cells lines at the concentration of 1 × 10-10 mol/L. It and auraptenol show 63 ug/mL MIC value against Klebsiella pneumoniae ATCC 4352 and Bacillus subtilis ATCC 9372.
    Targets: Antifection
    In vitro:
    Nat Prod Res. 2006 Aug;20(10):909-16.
    Antiproliferative effects of isopentenylated coumarins isolated from Phellolophium madagascariense Baker.[Pubmed: 16854718]

    METHODS AND RESULTS:
    From the leaves of Phellolophium madagascariense Baker (Apiaceae), an endemic herb to Madagascar, three known coumarins (osthol, Murraol and meranzin hydrate) have been isolated and identified. This is the first report of these compounds in this species. The structural elucidations were based on the analysis of physical and spectroscopic data.
    CONCLUSIONS:
    The anticancer activity of the three isolated compounds and of a synthetic sample of osthol was evaluated on L1210 mouse leukemia and on human prostatic cancer hormonosensitive LNCaP and hormonoindependent PC3 and DU145 cell lines.
    Molecules. 2017 Jul 1;22(7).
    Antibacterial Activities of Pyrenylated Coumarins from the Roots of Prangos hulusii.[Pubmed: 28671568 ]
    The dichloromethane extract of the roots of Prangos hulusii, a recently described endemic species from Turkey, has yielded nine known and one new prenylated coumarins.
    METHODS AND RESULTS:
    The structures were elucidated by spectroscopic methods and direct comparison with the reference compounds where available. The root extract and its prenylated coumarins exhibit antimicrobial activity against nine standard and six clinically isolated strains at a concentration between 5 and 125 µg/mL. In particular, the new coumarin, 4'-senecioiloxyosthol (1), displayed 5 µg/mL MIC (Minimum Inhibitory Concentration) value against Bacillus subtilis ATCC 9372, Murraol (4) and auraptenol (5) showed 63 µg/mL MIC value against Klebsiella pneumoniae ATCC 4352 and Bacillus subtilis ATCC 9372, and isoimperatorin (9) exhibited 16 µg/mL MIC value.
    Murraol Description
    Source: The herbs of Murraya exotica
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
    ChemFaces New Products and Compounds
    Selaginellin

    Catalog No: CFN95030
    CAS No: 941269-84-7
    Price: $/mg
    Euphorbia factor L25

    Catalog No: CFN95339
    CAS No: 303174-98-3
    Price: $368/5mg
    Andrographidine A

    Catalog No: CFN95210
    CAS No: 113963-37-4
    Price: $318/5mg
    Quercetin 3-O-beta-(6''-p-coumaroy...

    Catalog No: CFN95088
    CAS No: 143061-65-8
    Price: $338/10mg
    Neoarctin B

    Catalog No: CFN95243
    CAS No: 155969-67-8
    Price: $318/10mg
    Phyllanthusiin C

    Catalog No: CFN95260
    CAS No: 142674-52-0
    Price: $368/5mg
    Yuanhunine

    Catalog No: CFN95179
    CAS No: 104387-15-7
    Price: $368/5mg
    Daucoidin A

    Catalog No: CFN95275
    CAS No: 103629-87-4
    Price: $318/5mg
    Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

    Cell. 2018 Jan 11;172(1-2):249-261.e12.
    doi: 10.1016/j.cell.2017.12.019.
    IF=36.216(2019)

    PMID: 29328914

    Cell Metab. 2020 Mar 3;31(3):534-548.e5.
    doi: 10.1016/j.cmet.2020.01.002.
    IF=22.415(2019)

    PMID: 32004475

    Mol Cell. 2017 Nov 16;68(4):673-685.e6.
    doi: 10.1016/j.molcel.2017.10.022.
    IF=14.548(2019)

    PMID: 29149595

    ACS Nano. 2018 Apr 24;12(4): 3385-3396.
    doi: 10.1021/acsnano.7b08969.
    IF=13.903(2019)

    PMID: 29553709

    Nature Plants. 2016 Dec 22;3: 16206.
    doi: 10.1038/nplants.2016.205.
    IF=13.297(2019)

    PMID: 28005066

    Sci Adv. 2018 Oct 24;4(10): eaat6994.
    doi: 10.1126/sciadv.aat6994.
    IF=12.804(2019)

    PMID: 30417089
    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.8417 mL 19.2086 mL 38.4172 mL 76.8344 mL 96.043 mL
    5 mM 0.7683 mL 3.8417 mL 7.6834 mL 15.3669 mL 19.2086 mL
    10 mM 0.3842 mL 1.9209 mL 3.8417 mL 7.6834 mL 9.6043 mL
    50 mM 0.0768 mL 0.3842 mL 0.7683 mL 1.5367 mL 1.9209 mL
    100 mM 0.0384 mL 0.1921 mL 0.3842 mL 0.7683 mL 0.9604 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Zhong Cao Yao, 2016, 47(17):2993-6.
    Download citationShare Request full-text Chemical constituents isolated from fruits of Cnidium monnieri and their effects on proliferation of UMR106 cells[Reference: WebLink]
    To study the chemical constituents from the fruits of Cnidium monnieri and their effects on proliferation of UMR106 cells.
    METHODS AND RESULTS:
    The constituents were separated by column chromatography, and their structures were elucidated by spectroscopic data analyses. The proliferation of all isolated compounds on osteoblast-like UMR106 cells was determined. Nine compounds were isolated and identified as 5,7-dihydroxy-6,8-dimethoxy-2-methyl-4H-chromen-4-one (1), 5-hydroxy-2- hydroxymethyl-4H-chromen-4-one (2), (+)-marmesin (3), bergaptol (4), isobergapten (5), 7-hydroxy-8-(2',3'-dihydroxy-3'-methyl-butyl)-coumarin (6), Murraol (7), coniferyl aldehyde (8), and m-hydroxybenzoic acid (9). Compounds 1, 3, and 7 showed the significant proliferative activities on UMR106 cells lines at the concentration of 1 × 10⁻1⁰ mol/L and the proliferative ratios were 31.55%, 32.39% and 30.87%.
    CONCLUSIONS:
    Compounds 1-6 are isolated from the specie of Cnidium Cusson for the first time. Compounds 1, 3, and 7 increase UMR106 cells proliferation to some extent.
    Morusinol

    Catalog No: CFN97086
    CAS No: 62949-93-3
    Price: $318/5mg
    Isochlorogenic acid C

    Catalog No: CFN99120
    CAS No: 32451-88-0
    Price: $100/20mg
    Chrysin 6-C-arabinoside 8-C-glucos...

    Catalog No: CFN92284
    CAS No: 185145-33-9
    Price: $318/5mg
    Sibiricaxanthone B

    Catalog No: CFN90644
    CAS No: 241125-81-5
    Price: $238/20mg
    Decuroside I

    Catalog No: CFN95004
    CAS No: 96638-79-8
    Price: $318/5mg
    Tangeretin

    Catalog No: CFN90240
    CAS No: 481-53-8
    Price: $30/20mg
    2,4'-Dihydroxybenzophenone

    Catalog No: CFN92400
    CAS No: 606-12-2
    Price: $40/20mg