ChemFaces is a professional high-purity natural products manufacturer.
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2. Pharmacological research
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
|Size /Price /Stock
||10 mM * 1 mL in DMSO / $351.1 / In-stock||Other Packaging
||*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
More articles cited ChemFaces products.
Inflammation.2015, 38(4):1502-16Jour. of Stored Pro & Postharvest...2016...Polytechnic University of Catalon...2017...Viruses.2017, 9(10)Int J Mol Sci.2018, 19(2)Molecules.2018, 23(12):E3103Biochem Biophys Res Commun....2018...Toxicol In Vitro.2018, 52:94-105
J Herbmed Pharmacol.2018, 7(4):280-286Virulence.2018, 9(1):588-603BMC Microbiol.2019, 19(1):78Int J Mol Sci.2019, 20(23):E6071Molecules.2019, 24(10):E1926Exp Biol Med (Maywood)....2019...J Clin Med.2019, 8(10):E1664Plos One.2020, 10.1371
Neurochem Int.2020, 133:104629Biotechnol Bioeng....2020...Nutrients2020, 12(3):811.Phytomedicine.2020, 153440. Food Chem. 2020, 320:126530Bull. Pharm. Sci., Assiut Univers...2020...Rev. Chim.2020, 71(3),558-564
Our products had been exported to the following research institutions and universities, And still growing.
Calcutta University (India)Complutense University of Madrid (Spain)Pennsylvania State University (USA)Uniwersytet Gdański (Poland)
Massachusetts General Hospital (USA)Universidade Federal de Pernamb... (Brazil)Universidade da Beira Interior (Germany)Chang Gung University (Taiwan)
Heidelberg University (Germany)Sanford Burnham Prebys Medical ... (USA)Vin?a Institute of Nuclear Scie... (Serbia)
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1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
Sci Rep.2017, 7:40345Biochem Biophys Res Commun.2020, 527(4):889-895.J Ethnopharmacol.2017, 198:91-97BMC Complement Med Ther. 2020, 20(1):91.Molecules.2019, 24(9):E1719Phytomedicine.2018, 38:12-23Tea Res. Ins. Of China2017, 1-12J. Soc. Cosmet. Sci. Korea2016, 163-171Am J Chin Med.2016, 44(8):1719-1735Korean Journal of Pharmacognosy.2020, 51(2):100-106
Related Screening Libraries
|Size /Price /Stock
||10 mM * 100 uL in DMSO / Inquiry / In-stock |
10 mM * 1 mL in DMSO / Inquiry / In-stock
||Alkaloids Compound Library
|| N-trans-Caffeoyltyramine has both arginase inhibitory property and antioxidant capacity.|
|Pmio, 2016, 3(03):e64-e67. |
|In Vitro Mammalian Arginase Inhibitory and Antioxidant Effects of Amide Derivatives Isolated from the Hempseed Cakes (Cannabis sativa).[Reference: WebLink]|
METHODS AND RESULTS:
In an effort to identify novel inhibitors of arginase, a phytochemical study was performed on hempseed cakes (Cannabis sativa L.). It led to the isolation of a new lignanamide, cannabisin I ( 1), together with seven known lignanamides, cannabisins A, B, C, F, M, 3,3′-demethylgrossamide, grossamide, and two phenylpropanoid amides, N-trans-caffeoyltyramine and N-trans-caffeoyloctopamine, among which was later identified for the first time from C. sativa. Their structures were elucidated by comprehensive analysis of NMR spectroscopy and mass spectrometry data. These compounds were evaluated on mammal arginase (purified liver bovine arginase), showing that N-trans-caffeoyltyramine exhibited the higher activity with an IC50 value of 20.9 µM, which remains, however, less active than the reference compound S-(2-boronoethyl)-l-cysteine (IC50 = 4.3 µM). Radical scavenging capacity of these compounds was determined by the ORAC-FL method.
All tested cannabisins displayed antioxidant activity close to or better than the reference compounds. N-trans-Caffeoyltyramine has both arginase inhibitory property and antioxidant capacity.
||The roots of Litsea hypophaea
||Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
||Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: firstname.lastname@example.org
||The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
|Biochemical Systematics & Ecology, 2015, 58:265-269. |
|Phenylpropanoid amides from the roots of Solanum melongena L. (Solanaceae).[Reference: WebLink]|
METHODS AND RESULTS:
Phytochemical investigation of the roots of Solanum melongena L. led to the isolation of 16 phenylpropanoid amides (1–16). Their structures were identified by analysis of spectroscopic data and comparison with those reported in the literature.
This is the first report of the natural occurrence of N-trans-sinapoyloctopamine (9) and N-trans-caffeoyloctopamine (10). N-trans-feruloylnoradrenline (12) and N-cis-feruloylnoradrenline (16) were isolated from the genus Solanum for the first time.
Four compounds including 3-(4-hydroxyphenyl)-N-[2-(4-hydroxyphenyl)-2-methoxyethyl] acrylamide (5), 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)-2-methoxyethyl] acrylamide (6), N-trans-p-coumaroylnoradrenline (11), and N-cis-p-coumaroyloctopamine (15) were firstly reported from S. melongena. The chemotaxonomic significance of these compounds was summarized.