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    Natural Products
    N-trans-caffeoyloctopamine
    N-trans-caffeoyloctopamine
    Information
    CAS No. 1378868-10-0 Price $413 / 5mg
    Catalog No.CFN95264Purity>=98%
    Molecular Weight315.3Type of CompoundAlkaloids
    FormulaC17H17NO5Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $351.1 / In-stock
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    N-trans-caffeoyloctopamine

    N-trans-caffeoyloctopamine
    Product Name N-trans-caffeoyloctopamine
    CAS No.: 1378868-10-0
    Catalog No.: CFN95264
    Molecular Formula: C17H17NO5
    Molecular Weight: 315.3 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Source: The roots of Litsea hypophaea
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $413 / 5mg
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Alkaloids Compound Library
  • Biological Activity
    Description: N-trans-Caffeoyltyramine has both arginase inhibitory property and antioxidant capacity.
    In vitro:
    Pmio, 2016, 3(03):e64-e67.
    In Vitro Mammalian Arginase Inhibitory and Antioxidant Effects of Amide Derivatives Isolated from the Hempseed Cakes (Cannabis sativa).[Reference: WebLink]

    METHODS AND RESULTS:
    In an effort to identify novel inhibitors of arginase, a phytochemical study was performed on hempseed cakes (Cannabis sativa L.). It led to the isolation of a new lignanamide, cannabisin I ( 1), together with seven known lignanamides, cannabisins A, B, C, F, M, 3,3′-demethylgrossamide, grossamide, and two phenylpropanoid amides, N-trans-caffeoyltyramine and N-trans-caffeoyloctopamine, among which was later identified for the first time from C. sativa. Their structures were elucidated by comprehensive analysis of NMR spectroscopy and mass spectrometry data. These compounds were evaluated on mammal arginase (purified liver bovine arginase), showing that N-trans-caffeoyltyramine exhibited the higher activity with an IC50 value of 20.9 µM, which remains, however, less active than the reference compound S-(2-boronoethyl)-l-cysteine (IC50 = 4.3 µM). Radical scavenging capacity of these compounds was determined by the ORAC-FL method.
    CONCLUSIONS:
    All tested cannabisins displayed antioxidant activity close to or better than the reference compounds. N-trans-Caffeoyltyramine has both arginase inhibitory property and antioxidant capacity.
    N-trans-caffeoyloctopamine Description
    Source: The roots of Litsea hypophaea
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1716 mL 15.8579 mL 31.7158 mL 63.4317 mL 79.2896 mL
    5 mM 0.6343 mL 3.1716 mL 6.3432 mL 12.6863 mL 15.8579 mL
    10 mM 0.3172 mL 1.5858 mL 3.1716 mL 6.3432 mL 7.929 mL
    50 mM 0.0634 mL 0.3172 mL 0.6343 mL 1.2686 mL 1.5858 mL
    100 mM 0.0317 mL 0.1586 mL 0.3172 mL 0.6343 mL 0.7929 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Biochemical Systematics & Ecology, 2015, 58:265-269.
    Phenylpropanoid amides from the roots of Solanum melongena L. (Solanaceae).[Reference: WebLink]

    METHODS AND RESULTS:
    Phytochemical investigation of the roots of Solanum melongena L. led to the isolation of 16 phenylpropanoid amides (1–16). Their structures were identified by analysis of spectroscopic data and comparison with those reported in the literature.
    CONCLUSIONS:
    This is the first report of the natural occurrence of N-trans-sinapoyloctopamine (9) and N-trans-caffeoyloctopamine (10). N-trans-feruloylnoradrenline (12) and N-cis-feruloylnoradrenline (16) were isolated from the genus Solanum for the first time. Four compounds including 3-(4-hydroxyphenyl)-N-[2-(4-hydroxyphenyl)-2-methoxyethyl] acrylamide (5), 3-(4-hydroxy-3-methoxyphenyl)-N-[2-(4-hydroxyphenyl)-2-methoxyethyl] acrylamide (6), N-trans-p-coumaroylnoradrenline (11), and N-cis-p-coumaroyloctopamine (15) were firstly reported from S. melongena. The chemotaxonomic significance of these compounds was summarized.
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