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    Natural Products
    Neoglycyrol
    Information
    CAS No. 23013-84-5 Price $338 / 10mg
    Catalog No.CFN90792Purity>=98%
    Molecular Weight366.4Type of CompoundCoumarins
    FormulaC21H18O6Physical DescriptionPowder
    Download Manual    COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $186.7 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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  • Package
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    Neoglycyrol

    Neoglycyrol
    Product Name Neoglycyrol
    CAS No.: 23013-84-5
    Catalog No.: CFN90792
    Molecular Formula: C21H18O6
    Molecular Weight: 366.4 g/mol
    Purity: >=98%
    Type of Compound: Coumarins
    Physical Desc.: Powder
    Source: The roots of Glycyrrhiza uralensis Fisch.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $338 / 10mg
    Inquire / Order: manager@chemfaces.com
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    1 Building, No. 83, CheCheng Rd., Wuhan Economic and Technological Development Zone, Wuhan, Hubei 430056, PRC
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cardioprotective Compound Library
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  • Biological Activity
    Description: Neoglycyrol shows some cardioprotective effects .
    In vitro:
    Zhejiang Da Xue Xue Bao Yi Xue Ban. 2015 Mar;44(2):145-53.
    Screening of active compounds with myocardial protective effects from Tongmai Yangxin pill[Pubmed: 26038132]
    Based on cell model and HPLC-MS technology, to screen myocardial protection active compounds from traditional patent medicine Tongmai Yangxin pill (TMYXP).
    METHODS AND RESULTS:
    Fractions of TMYXP were prepared by high performance liquid preparation technology. The cardioprotective effects of prepared fractions were tested on H2O2 oxidation-damaged H9c2 myocardiocytes. The active components were analyzed by high performance liquid chromatography (HPLC) coupled with high resolution mass spectrometry. The possible active compounds were putatively identified by comparison of their MS ions and molecular weight with literatures. Ten TMYXP components presented significant myocardial protective activities, 5 of which were investigated and presented good dose-effect relationships. Their median effective concentrations (EC50) were respectively 11.66, 17.44, 13.10, 7.332, 15.15 μg/mL. Totally, 11 potential active compounds were analyzed and identified, including Glycyrrhizic acid, Glycycoumarin, Licoisoflavone, Ophiopogonin D', Licoricon, Gancaonin L, Neoglycyrol, Emodin, Angeloylgomisin H, Angeloylgomisin Q and Glyasperin A.
    CONCLUSIONS:
    The myocardial protection active compounds of TMYXP were screened successfully.
    Neoglycyrol Description
    Source: The roots of Glycyrrhiza uralensis Fisch.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.7293 mL 13.6463 mL 27.2926 mL 54.5852 mL 68.2314 mL
    5 mM 0.5459 mL 2.7293 mL 5.4585 mL 10.917 mL 13.6463 mL
    10 mM 0.2729 mL 1.3646 mL 2.7293 mL 5.4585 mL 6.8231 mL
    50 mM 0.0546 mL 0.2729 mL 0.5459 mL 1.0917 mL 1.3646 mL
    100 mM 0.0273 mL 0.1365 mL 0.2729 mL 0.5459 mL 0.6823 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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