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Neonuezhenide
Neonuezhenide
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Neonuezhenide
Price:
CAS No.: 96382-91-1
Catalog No.: CFN89171
Molecular Formula: C31H42O18
Molecular Weight: 702.65 g/mol
Purity: >=98%
Type of Compound: Iridoids
Physical Desc.: Oil
Source: The rhizomes of Cyperus rotundus.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Neonuezhenide exhibits strong antioxidant effect against hemolysis of red blood cells induced by free radicals.
In vitro:
Chem Pharm Bull (Tokyo). 2001 Jun;49(6):780-4.
Antioxidative glucosides from the fruits of Ligustrum lucidum.[Pubmed: 11411539]
.
METHODS AND RESULTS:
The ethanol extract of the fruits of Ligustrum lucidum was shown to have inhibitory effects on the hemolysis of red blood cells induced by 2,2'-azo-bis-(2-amidinopropane) dihydrochloride. Bioassay-guided analysis led to the isolation of ten secoiridoid glucosides. Two of them were new, lucidumosides C and D. Their structures were elucidated by spectroscopic methods. The other eight compounds were identified as oleoside dimethyl ester, ligustroside, oleuropein, nuezhenide, isonuezhenide, Neonuezhenide, lucidumoside A and lucidumoside B.
CONCLUSIONS:
Five compounds, oleoside dimethyl ester, oleuropein, Neonuezhenide, lucidumoside B and lucidumoside C, exhibited strong antioxidant effect against hemolysis of red blood cells induced by free radicals.
Neonuezhenide Description
Source: The rhizomes of Cyperus rotundus.
Solvent: DMSO, Pyridine, Methanol, Ethanol, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 1.4232 mL 7.1159 mL 14.2318 mL 28.4637 mL 35.5796 mL
5 mM 0.2846 mL 1.4232 mL 2.8464 mL 5.6927 mL 7.1159 mL
10 mM 0.1423 mL 0.7116 mL 1.4232 mL 2.8464 mL 3.558 mL
50 mM 0.0285 mL 0.1423 mL 0.2846 mL 0.5693 mL 0.7116 mL
100 mM 0.0142 mL 0.0712 mL 0.1423 mL 0.2846 mL 0.3558 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
Protocol
Structure Identification:
Chem Pharm Bull (Tokyo). 2016;64(1):73-7.
New Iridoid Glycosides with Antidepressant Activity Isolated from Cyperus rotundus.[Pubmed: 26726748]

METHODS AND RESULTS:
Based on bioactive screening results, two new iridoid glycosides, named rotunduside G (1) and rotunduside H (2), were isolated from the rhizomes of Cyperus rotundus, together with four known ones, negundoside (3), nishindaside (4), isooleuropein (5) and Neonuezhenide (6). Their structures were elucidated on the basis of spectroscopic methods and from literature values.
CONCLUSIONS:
In mice models of despair, 1 and 2 showed significant antidepressant activity.
Arctiin

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CAS No: 20362-31-6
Price: $30/20mg
Ginkgolide C

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CAS No: 15291-76-6
Price: $30/20mg
Piperine

Catalog No: CFN99919
CAS No: 94-62-2
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Daidzin

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Price: $40/20mg
Isoimperatorin

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CAS No: 482-45-1
Price: $40/20mg
Acetyleugenol

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Tectoridin

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Ardisiacrispin A

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Soyasapogenol C

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Curzerenone

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