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Pilloin
Pilloin
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Pilloin
Price: $218 / 10mg
CAS No.: 32174-62-2
Catalog No.: CFN96503
Molecular Formula: C17H14O6
Molecular Weight: 314.29 g/mol
Purity: >=98%
Type of Compound: Flavonoids
Physical Desc.: Powder
Source: The herbs of Marrubium cylleneum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison (Web)  (SDF)
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* Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / $109.4 / In-stock
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Pilloin exerts a cytotoxic action targeted at the transformed lymphoblasts.
In vitro:
Pharmaceutical Biology, 2008, 40(4):245-248.
Effects of the Flavonoid Pilloin Isolated from Marrubium cylleneum on Mitogen-Induced Lymphocyte Transformation[Reference: WebLink]
Flavonoids are known to exhibit a wide range of biological functions.
METHODS AND RESULTS:
In the present study, the possible immunomodulatory and cytotoxic effects of Pilloin, a flavone extracted from the Greek endemic herb Marrubium cylleneum were investigated by using the in vitro lymphocyte transformation and the cytotoxicity assays, respectively. Apigenin was used as the control flavonoid.
CONCLUSIONS:
Pilloin exerted a cytotoxic action targeted at the transformed lymphoblasts. On the other hand, the glycosylated flavonoid chrysoeriol-7- O -ß-D-(3β- E-p -coumaroyl)-glucopyranoside was inactive, providing further evidence that glycosylation may eliminate the effects of aglycones.
Pilloin Description
Source: The herbs of Marrubium cylleneum.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)

PMID: 29328914

Cell Metab. 2020 Mar 3;31(3):534-548.e5.
doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)

PMID: 32004475

Mol Cell. 2017 Nov 16;68(4):673-685.e6.
doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)

PMID: 29149595

ACS Nano. 2018 Apr 24;12(4): 3385-3396.
doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)

PMID: 29553709

Nature Plants. 2016 Dec 22;3: 16206.
doi: 10.1038/nplants.2016.205.
IF=13.297(2019)

PMID: 28005066

Sci Adv. 2018 Oct 24;4(10): eaat6994.
doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)

PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1818 mL 15.9089 mL 31.8177 mL 63.6355 mL 79.5444 mL
5 mM 0.6364 mL 3.1818 mL 6.3635 mL 12.7271 mL 15.9089 mL
10 mM 0.3182 mL 1.5909 mL 3.1818 mL 6.3635 mL 7.9544 mL
50 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.2727 mL 1.5909 mL
100 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.6364 mL 0.7954 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Price: $30/20mg
Rhaponiticin

Catalog No: CFN98569
CAS No: 155-58-8
Price: $60/20mg
Swertiajaponin

Catalog No: CFN90652
CAS No: 6980-25-2
Price: $218/10mg
Ferruginol

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CAS No: 514-62-5
Price: $ / mg
Ginsenoside Ra2

Catalog No: CFN93293
CAS No: 83459-42-1
Price: $218/5mg
Liquiritigenin

Catalog No: CFN99156
CAS No: 578-86-9
Price: $30/20mg
Kaempferol-3-O-galactoside

Catalog No: CFN92079
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Price: $238/10mg
Momordicine I

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Price: $368/10mg
Capsanthin

Catalog No: CFN70366
CAS No: 465-42-9
Price: $ / mg
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