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    Natural Products
    Pilloin
    Pilloin
    Information
    CAS No. 32174-62-2 Price $218 / 10mg
    Catalog No.CFN96503Purity>=98%
    Molecular Weight314.29Type of CompoundFlavonoids
    FormulaC17H14O6Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    Address: No. 83, CheCheng Rd., WETDZ, Wuhan, Hubei 430056, PRC
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    * Packaging according to customer requirements(5mg, 10mg, 20mg and more). We shipped via FedEx, DHL, UPS, EMS and others courier.
    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / $120.4 / In-stock
    Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
    Our products had been exported to the following research institutions and universities, And still growing.
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    Pilloin

    Pilloin
    Product Name Pilloin
    CAS No.: 32174-62-2
    Catalog No.: CFN96503
    Molecular Formula: C17H14O6
    Molecular Weight: 314.29 g/mol
    Purity: >=98%
    Type of Compound: Flavonoids
    Physical Desc.: Powder
    Source: The herbs of Marrubium cylleneum.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price: $218 / 10mg
    Inquire / Order: manager@chemfaces.com
    Technical Inquiries: service@chemfaces.com
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  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Cytotoxic Compound Library
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  • Biological Activity
    Description: Pilloin exerts a cytotoxic action targeted at the transformed lymphoblasts.
    In vitro:
    Pharmaceutical Biology, 2008, 40(4):245-248.
    Effects of the Flavonoid Pilloin Isolated from Marrubium cylleneum on Mitogen-Induced Lymphocyte Transformation[Reference: WebLink]
    Flavonoids are known to exhibit a wide range of biological functions.
    METHODS AND RESULTS:
    In the present study, the possible immunomodulatory and cytotoxic effects of Pilloin, a flavone extracted from the Greek endemic herb Marrubium cylleneum were investigated by using the in vitro lymphocyte transformation and the cytotoxicity assays, respectively. Apigenin was used as the control flavonoid.
    CONCLUSIONS:
    Pilloin exerted a cytotoxic action targeted at the transformed lymphoblasts. On the other hand, the glycosylated flavonoid chrysoeriol-7- O -ß-D-(3β- E-p -coumaroyl)-glucopyranoside was inactive, providing further evidence that glycosylation may eliminate the effects of aglycones.
    Pilloin Description
    Source: The herbs of Marrubium cylleneum.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 3.1818 mL 15.9089 mL 31.8177 mL 63.6355 mL 79.5444 mL
    5 mM 0.6364 mL 3.1818 mL 6.3635 mL 12.7271 mL 15.9089 mL
    10 mM 0.3182 mL 1.5909 mL 3.1818 mL 6.3635 mL 7.9544 mL
    50 mM 0.0636 mL 0.3182 mL 0.6364 mL 1.2727 mL 1.5909 mL
    100 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.6364 mL 0.7954 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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