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1. Reference standards
2. Pharmacological research
3. Inhibitors
Quercetin 3,3'-dimethyl ether
Citing Use of our Products
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
| Size /Price /Stock |
10 mM * 1 mL in DMSO / Inquiry |
Other Packaging |
*Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap |
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Inflammation.2015, 38(4):1502-16Plants (Basel).2020, 9(11):1535.FASEB J.2019, 33(8):9685-9694Biochem Biophys Res Commun....2018...Phytomedicine.2018, 38:45-56Chemistry of Vegetable Raw Materi...2019...Toxicol Appl Pharmacol....2022...Int J Mol Med.2019, 43(6):2516-2522
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Our products had been exported to the following research institutions and universities, And still growing.
University of South Australia (Australia)National Research Council of Ca... (Canada)Nicolaus Copernicus Uniwersity (Poland)Wageningen University (Netherlands)
VIB Department of Plant Systems... (Belgium)University of Minnesota (USA)Leibniz-Institut für Pflanzenb... (Germany)Kyung Hee University (Korea)
Calcutta University (India)University of Auckland (New Zealand)University of Virginia (USA)
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Quercetin 3,3'-dimethyl ether
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manager@chemfaces.com
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service@chemfaces.com
Tel:
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BMC Complement Altern Med.2019, 19(1):11RSC Advances2017, 86Korean Journal of Pharmacognosy2018, 49(1):76-83Fitoterapia.2022, 105141.The Japan Society for Analytical Chemistry2018, 67(4):201-206Nat Prod Sci.2016, 22(2)Processes2021, 9(5),831.ACS Nano.2018, 12(4):3385-3396Oncol Rep.2021, 46(1):143.Biochem Pharmacol.2017, 130:10-20
Related Screening Libraries
| Description: |
Quercetin 3,3'-dimethyl ether may have moderate estrogenic activity. |
| Targets: |
Estrogen receptor | Progestogen receptor |
| In vitro: |
| Phytochemistry. 2002 Jun;60(4):385-7. | | A benzoquinone and flavonoids from Cyperus alopecuroides.[Pubmed: 12031430] |
METHODS AND RESULTS:
A benzoquinone, named alopecuquinone, was isolated from the ethanol extract of the inflorescences of Cyperus alopecuroides.
Its structure was primarily elucidated by spectroscopic analysis including 1H, 13C NMR, APT, HMQC, 1H-1H COSY and CIMS. The known flavonoids, vicenin 2, orientin, diosmetin, Quercetin 3,3'-dimethyl ether and its 3,4'-dimethyl ether, were also isolated and characterized.
CONCLUSIONS:
The ethanol extract of the plant material showed moderate estrogenic activity using a strain of Saccharomyces cerevisiae. |
|
Quercetin 3,3'-dimethyl ether Description
| Source: |
The fruits of Narthecium ossifragum. |
| Solvent: |
Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| Storage: |
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
|
| After receiving: |
The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling. |
ChemFaces New Products and Compounds
Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals
Cell. 2018 Jan 11;172(1-2):249-261.e12. doi: 10.1016/j.cell.2017.12.019.
IF=36.216(2019)PMID: 29328914
Cell Metab. 2020 Mar 3;31(3):534-548.e5. doi: 10.1016/j.cmet.2020.01.002.
IF=22.415(2019)PMID: 32004475
Mol Cell. 2017 Nov 16;68(4):673-685.e6. doi: 10.1016/j.molcel.2017.10.022.
IF=14.548(2019)PMID: 29149595
ACS Nano. 2018 Apr 24;12(4): 3385-3396. doi: 10.1021/acsnano.7b08969.
IF=13.903(2019)PMID: 29553709
Nature Plants. 2016 Dec 22;3: 16206. doi: 10.1038/nplants.2016.205.
IF=13.297(2019)PMID: 28005066
Sci Adv. 2018 Oct 24;4(10): eaat6994. doi: 10.1126/sciadv.aat6994.
IF=12.804(2019)PMID: 30417089
Calculate Dilution Ratios(Only for Reference)
|
1 mg |
5 mg |
10 mg |
20 mg |
25 mg |
| 1 mM |
3.0277 mL |
15.1387 mL |
30.2773 mL |
60.5547 mL |
75.6934 mL |
| 5 mM |
0.6055 mL |
3.0277 mL |
6.0555 mL |
12.1109 mL |
15.1387 mL |
| 10 mM |
0.3028 mL |
1.5139 mL |
3.0277 mL |
6.0555 mL |
7.5693 mL |
| 50 mM |
0.0606 mL |
0.3028 mL |
0.6055 mL |
1.2111 mL |
1.5139 mL |
| 100 mM |
0.0303 mL |
0.1514 mL |
0.3028 mL |
0.6055 mL |
0.7569 mL |
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
| Structure Identification: |
| Phytochemistry. 2016 Dec;132:76-85. | | Toxic aromatic compounds from fruits of Narthecium ossifragum L.[Pubmed: 27720435 ] | The intake of Narthecium ossifragum, commonly known as bog asphodel, has been associated with toxic effects observed in sheep for centuries. Although the plant has been studied for five centuries little is known about its chemical constituents.
METHODS AND RESULTS:
Six previously undescribed natural products, naringenin(3 → 6″)luteolin, naringenin(3 → 6″)chrysoeriol, liovil 4-O-β-glucopyranoside, 2,6-dimethoxy cinnamic acid, (E)-4-(3-hydroxy-2,2-dimethylchroman-6-yl)but-3-en-2-one and (E)-4-(4-(((E)-4-hydroxy-3-methylbut-2-en-1-yl)oxy)phenyl)but-3-en-2-one, have been identified from fruits of N. ossifragum for the first time. In addition, the rare natural product 4-hydroxy-3-(3-methylbut-2-enyl)benzaldehyde and the five known compounds 4-hydroxycinnamic acid, Quercetin 3,3'-dimethyl ether, quercetin 3,7-dimethyl ether, chrysoeriol 7-O-β-glucopyranoside and the di-C-glycosylflavone isoschaftoside were all characterized for the first time from the fruits of N. ossifragum.
CONCLUSIONS:
The discovery of sufficient amounts of 4-hydroxy-3-(3-methylbut-2-enyl)benzaldehyde in fresh plant material of N. ossifragum to allow complete structure elucidation by NMR and HRMS supports the possibility that fungi associated with N. ossifragum may be able to produce enough toxins to play a significant role in the pathogenicity of N. ossifragum. |
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