Resorcinol | CAS:108-46-3 | Manufacturer ChemFaces

Resorcinol

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Description:

Resorcinol is an antiseptic and a disinfectant, and a chemical intermediate for the production of many other pharmaceuticals，is used to treat acne, seborrheic dermatitis, eczema, psoriasis, and other skin disorders.

In vivo:

Clin Exp Dermatol. 2010 Jan;35(1):36-40.

Resorcinol peels as a possible self-treatment of painful nodules in hidradenitis suppurativa.[Pubmed: 19549239 ]

Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by abscess formation localized to apocrine sweat gland-bearing skin. The most important factor in patients' overall assessment of disease severity is pain. The duration of abscesses takes days to weeks and are always painful. AIM: To assess the efficacy of self-treatment with topical 15% Resorcinol in an open study.
METHODS AND RESULTS:
The case notes of 12 women with stage 1 or 2 HS treated with topical Resorcinol and followed up for at least 1 year were reviewed. The patients rated the efficacy of treatment on global maximum pain of nodules and abscesses on a visual analogue scale (VAS) and by self-report of the mean duration (days) of a painful lesion. RESULTS: All patients experienced a significant decrease in pain as assessed by VAS and reported a reduction in mean duration of the painful abscesses.
CONCLUSIONS:
Topical treatment with 15% Resorcinol reduced pain from painful nodules in all patients with HS. Further trials are warranted to confirm these results.

Resorcinol Description

Source:	The herbs of Cordia ecalyculata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage:	Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C). Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com
After receiving:	The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.

Structure Identification:

Phys Chem Chem Phys. 2015 Feb 4;17(7):5236-47.

Structural investigation of resorcinol based symmetrical banana mesogens by XRD, NMR and polarization measurements.[Pubmed: 25603887]

Synthesis and structural characterization of two novel symmetrical banana mesogens built from Resorcinol with seven phenyl rings linked by ester and imine with a terminal dodecyl/dodecyloxy chain has been carried out. Density functional theory (DFT) has been employed for obtaining the geometry optimized structures, the dipole moments and (13)C NMR chemical shifts. The HOPM and DSC studies revealed enantiotropic B2 and B7 phases for the dodecyl and dodecyloxy homologs respectively. The powder X-ray studies of both the mesogens indicate the presence of layer ordering. The polarization measurements reveal an anti-ferroelectric switching for the B2 phase of the dodecyl homolog whose structure has been identified as SmCSPA. The B7 phase of the dodecyloxy homolog was found to be non-switchable. High resolution (13)C NMR study of the dodecyl homolog in its mesophase has been carried out. (13)C-(1)H dipolar couplings obtained from the 2-dimensional separated local field spectroscopy experiment were used to obtain the orientational order parameters of the different segments of the mesogen. Very large (13)C-(1)H dipolar couplings observed for the carbons of the central phenyl ring (9.7-12.3 kHz) in comparison to the dipolar couplings of those of the side arm phenyl rings (less than 3 kHz) are a direct consequence of the ordering in the banana phase and the shape of the molecule. From the ratio of the local order parameter values, the bent-angle of the mesogen could be determined in a straight forward manner to be 120.5°.

Product Name	Resorcinol
Price:	$30 / 20mg
CAS No.:	108-46-3
Catalog No.:	CFN99089
Molecular Formula:	C₆H₆O₂
Molecular Weight:	110.1 g/mol
Purity:	>=98%
Type of Compound:	Phenols
Physical Desc.:	Cryst.
Source:	The herbs of Cordia ecalyculata
Solvent:	Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download:	COA MSDS SDF Manual
Similar structural:	Comparison (Web) (SDF)
Guestbook:

Size /Price /Stock	10 mM * 100 uL in DMSO / Inquiry / In-stock 10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries	Analgesia Compound Library Phenols Compound Library

	1 mg	5 mg	10 mg	20 mg	25 mg
1 mM	9.0827 mL	45.4133 mL	90.8265 mL	181.653 mL	227.0663 mL
5 mM	1.8165 mL	9.0827 mL	18.1653 mL	36.3306 mL	45.4133 mL
10 mM	0.9083 mL	4.5413 mL	9.0827 mL	18.1653 mL	22.7066 mL
50 mM	0.1817 mL	0.9083 mL	1.8165 mL	3.6331 mL	4.5413 mL
100 mM	0.0908 mL	0.4541 mL	0.9083 mL	1.8165 mL	2.2707 mL

CFN90452	Sesamol	533-31-3	138.12	C₇H₆O₃
CFN98398	Isotachioside	31427-08-4	302.3	C₁₃H₁₈O₈
CFN97527	4-Hydroxy-2-methoxyphenol 1-O-(6-O-syringoyl)glucoside	945259-61-0	482.4	C₂₂H₂₆O₁₂
CFN95381	New compound 14	N/A	524.5	C₂₄H₂₈O₁₃
CFN99092	Tachioside	109194-60-7	302.3	C₁₃H₁₈O₈
CFN98027	3,4-Dimethoxyphenol	2033-89-8	154.2	C₈H₁₀O₃
CFN97405	3,4-Dimethoxyphenyl beta-D-glucoside	84812-00-0	316.3	C₁₄H₂₀O₈
CFN98343	Phlorin	28217-60-9	288.3	C₁₂H₁₆O₈
CFN99366	2,4,6-Trimethoxyphenol 1-O-beta-D-glucopyranoside	125288-25-7	346.3	C₁₅H₂₂O₉
CFN99329	1,2-Benzenediol	120-80-9	110.1	C₆H₆O₂