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Taberdivarine H
Taberdivarine H
ChemFaces products have been cited in many studies from excellent and top scientific journals
Product Name Taberdivarine H
Price:
CAS No.: 1662688-34-7
Catalog No.: CFN96650
Molecular Formula: C20H22N2O2
Molecular Weight: 322.41 g/mol
Purity: >=98%
Type of Compound: Alkaloids
Physical Desc.: Powder
Source: The aerial parts of Tabernaemontana officinalis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Download: COA    MSDS
Similar structural: Comparison
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According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
Other Packaging *Packaging according to customer requirements(100uL/well, 200uL/well and more), and Container use Storage Tube With Screw Cap
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Related Screening Libraries
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10 mM * 1 mL in DMSO / Inquiry / In-stock
Related Libraries
Biological Activity
Description: Taberdivarine H is a natural product from Tabernaemontana officinalis.
In vitro:
Phytochemistry. 2015 Dec;120:46-52.
Cytotoxic indole alkaloids from Tabernaemontana officinalis.[Pubmed: 25687604 ]

METHODS AND RESULTS:
Continued interest in cytotoxic alkaloids resulted in the isolation of 37 alkaloids including 29 known monoterpenoid indole alkaloids from the aerial parts of Tabernaemontana officinalis. Of the remaining 8 alkaloids, six were bisindole alkaloids named taberdivarine A, taberdivarine B, taberdivarine C, taberdivarine D, taberdivarine E, taberdivarine F (1-6) and the two were monomers named taberdivarine G and Taberdivarine H (7-8).
CONCLUSIONS:
Alkaloids 1 and 2 are voaphylline-vobasinyl type bisindole alkaloids, a structural type previously unknown, while 3-6 exhibited cytotoxicity against three human cancer cell lines HeLa, MCF-7, and SW480 with IC50 values ranging from 1.42 to 11.35 μM.
Taberdivarine H Description
Source: The aerial parts of Tabernaemontana officinalis.
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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Recently, ChemFaces products have been cited in many studies from excellent and top scientific journals

Cell. 2018 Jan 11;172(1-2):249-261.e12.
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PMID: 29328914

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doi: 10.1016/j.cmet.2020.01.002.
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Sci Adv. 2018 Oct 24;4(10): eaat6994.
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Calculate Dilution Ratios(Only for Reference)
1 mg 5 mg 10 mg 20 mg 25 mg
1 mM 3.1016 mL 15.5082 mL 31.0164 mL 62.0328 mL 77.541 mL
5 mM 0.6203 mL 3.1016 mL 6.2033 mL 12.4066 mL 15.5082 mL
10 mM 0.3102 mL 1.5508 mL 3.1016 mL 6.2033 mL 7.7541 mL
50 mM 0.062 mL 0.3102 mL 0.6203 mL 1.2407 mL 1.5508 mL
100 mM 0.031 mL 0.1551 mL 0.3102 mL 0.6203 mL 0.7754 mL
* Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
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Gypenoside XLIX

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CAS No: 94987-08-3
Price: $118/20mg
Asperuloside

Catalog No: CFN99467
CAS No: 14259-45-1
Price: $118/20mg
Canthin-6-one

Catalog No: CFN98730
CAS No: 479-43-6
Price: $318/5mg
Isochlorogenic acid A

Catalog No: CFN99118
CAS No: 2450-53-5
Price: $50/20mg
Chebulanin

Catalog No: CFN92294
CAS No: 166833-80-3
Price: $ / mg
Soybean phospholipid

Catalog No: CFN93800
CAS No: 8002-43-5
Price: $30/20mg
Osthol

Catalog No: CFN98765
CAS No: 484-12-8
Price: $30/20mg
Geraniin

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gamma-Mangostin

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CAS No: 31271-07-5
Price: $70/20mg
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