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    Natural Products
    Thalifoline
    Information
    CAS No. 21796-15-6 Price
    Catalog No.CFN92336Purity>=98%
    Molecular Weight207.2Type of CompoundAlkaloids
    FormulaC11H13NO3Physical DescriptionPowder
    Download     COA    MSDS    SDFSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Thalifoline

    Thalifoline
    Product Name Thalifoline
    CAS No.: 21796-15-6
    Catalog No.: CFN92336
    Molecular Formula: C11H13NO3
    Molecular Weight: 207.2 g/mol
    Purity: >=98%
    Type of Compound: Alkaloids
    Physical Desc.: Powder
    Targets: Antifection
    Source: The herbs of Thalictrum aquilegifolium
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
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  • FEBS Lett.2015, 589(1):182-7
  • Molecules.2020, 25(9):2081.
  • Korean Journal of Pharmacognosy2018, 49(1):76-83
  • J Biol Chem.2014, 289(3):1723-31
  • Cell Physiol Biochem.2017, 44(4):1381-1395
  • Evid Based Complement Alternat Med.2020, 2020:1970349.
  • Nutrients.2019, 11(6):E1380
  • Food Chem.2017, 221:1135-1144
  • Biol Pharm Bull.2018, 41(11):1685-1693
  • Int J Mol Sci. 2014, 15(5):8443-57
  • Related Screening Libraries
    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
    10 mM * 1 mL in DMSO / Inquiry / In-stock
    Related Libraries
  • Antifungal Compound Library
  • Alkaloids Compound Library
  • Antifection Inhibitor Library
  • Biological Activity
    Description: Thalifoline shows antifungal activity, with 100 ug against Fusarium oxysporum f. sp. lycopersici.
    Targets: Antifection
    In vitro:
    Phytochemistry Letters, 2011 , 4 (1) :22-5.
    Monophyllidin, a new alkaloid L-proline derivative from Zanthoxylum monophyllum[Reference: WebLink]

    METHODS AND RESULTS:
    A new L-proline derivative, monophyllidin (1), together with four known compounds, Thalifoline (2), berberine (3), jathrorrhizine (4) and 3β-glucositosterol (5) has been isolated from the bark of Zanthoxylum monophyllum. The structure of compound 1 was elucidated on the basis of extensive spectroscopic data analysis. Characterization of compounds 2–5 was based on spectral analysis and comparison with reported data.
    CONCLUSIONS:
    Compound 3 showed antibacterial activity against the five bacterial strains used, while 1, 4 and 5 presented only antibacterial activity against Enterococcus faecalis. Compounds 2 and 4 showed antifungal activity, with 100 μg against Fusarium oxysporum f. sp. lycopersici.
    Thalifoline Description
    Source: The herbs of Thalictrum aquilegifolium
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 4.8263 mL 24.1313 mL 48.2625 mL 96.5251 mL 120.6564 mL
    5 mM 0.9653 mL 4.8263 mL 9.6525 mL 19.305 mL 24.1313 mL
    10 mM 0.4826 mL 2.4131 mL 4.8263 mL 9.6525 mL 12.0656 mL
    50 mM 0.0965 mL 0.4826 mL 0.9653 mL 1.9305 mL 2.4131 mL
    100 mM 0.0483 mL 0.2413 mL 0.4826 mL 0.9653 mL 1.2066 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    Australian Journal of Chemistry.1981;34(1):195 - 207.
    Alkaloids of Cryptocarya longifolia: X-Ray Crystal Structure of Thalifoline and Longifolonine.[Reference: WebLink]

    METHODS AND RESULTS:
    The known alkaloids reticuline (1), coclaurine (3), N-methylcoclaurine (2), laurotetanine (7), N-methyl-laurotetanine (8), laurolitsine (10), isoboldine (9), norisocorydine (6), norargemonine (ll), bisnorargemonine (12), Thalifoline (16) and scoulerine (13) were isolated from the New Caledonian plant Cryptocarya longifolia together with two new bases, longifolidine (4) and longifolonine (14).
    CONCLUSIONS:
    Spectroscopic methods were used for identification and structural investigation, and X-ray crystallographic analysis to determine the structures of Thalifoline and longifolonine.
    Chemistry of Natural Compounds, 2017,53( 3) : 504–7.
    Isoquinoline Alkaloids from Michelia fuscata[Reference: WebLink]

    METHODS AND RESULTS:
    Two new isoquinoline alkaloids, fuscatine A (1) and fuscatine B (2), along with 21 compounds including eight isoquinoline alkaloids, norThalifoline (3), Thalifoline (4), corydaldine (5), N-methylcorydaldine (6), (6,7-dimethoxyisoquinolinyl)-(4′-methoxyphenyl)-methanone (7),(6,7-dimethoxyisoquinolinyl)-(4′-hydroxyphenyl)-methanone (8), liriodenine (9), and corydine (10); two steroids, β-sitosterone and stigmasterone; six benzenoids, p-hydroxybenzaldehyde, p-hydroxybenzoic acid, 3,4-dimethoxybenzoic acid, methylparaben, syringic acid, and coniferyl aldehyde; one quinone 2,6-dimethoxy-p-benzoquinone, and one sesquiterpene, caryophyllene oxide, are isolated from the stems of Michelia fuscata (Magnoliaceae).
    CONCLUSIONS:
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