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    Natural Products
    Triptocalline A
    Information
    CAS No. 201534-10-3 Price
    Catalog No.CFN96477Purity>=98%
    Molecular Weight442.64Type of CompoundTriterpenoids
    FormulaC28H42O4Physical DescriptionPowder
    Download     COA    MSDSSimilar structuralComparison (Web)  (SDF)
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    According to end customer requirements, ChemFaces provide solvent format. This solvent format of product intended use: Signaling Inhibitors, Biological activities or Pharmacological activities.
    Size /Price /Stock 10 mM * 1 mL in DMSO / Inquiry
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    Triptocalline A

    Triptocalline A
    Product Name Triptocalline A
    CAS No.: 201534-10-3
    Catalog No.: CFN96477
    Molecular Formula: C28H42O4
    Molecular Weight: 442.64 g/mol
    Purity: >=98%
    Type of Compound: Triterpenoids
    Physical Desc.: Powder
    Source: The roots of Tripterygium wilfordii Hook.f.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Price:
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    Size /Price /Stock 10 mM * 100 uL in DMSO / Inquiry / In-stock
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  • Biological Activity
    Description: Triptocalline A shows an inhibitory effect on rat lens aldose reductase.
    Triptocalline A Description
    Source: The roots of Tripterygium wilfordii Hook.f.
    Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
    Storage: Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 24 months(2-8C).

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20C. Generally, these will be useable for up to two weeks. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please email to: service@chemfaces.com

    After receiving: The packaging of the product may have turned upside down during transportation, resulting in the natural compounds adhering to the neck or cap of the vial. take the vial out of its packaging and gently shake to let the compounds fall to the bottom of the vial. for liquid products, centrifuge at 200-500 RPM to gather the liquid at the bottom of the vial. try to avoid loss or contamination during handling.
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    Calculate Dilution Ratios(Only for Reference)
    1 mg 5 mg 10 mg 20 mg 25 mg
    1 mM 2.2592 mL 11.2959 mL 22.5917 mL 45.1834 mL 56.4793 mL
    5 mM 0.4518 mL 2.2592 mL 4.5183 mL 9.0367 mL 11.2959 mL
    10 mM 0.2259 mL 1.1296 mL 2.2592 mL 4.5183 mL 5.6479 mL
    50 mM 0.0452 mL 0.2259 mL 0.4518 mL 0.9037 mL 1.1296 mL
    100 mM 0.0226 mL 0.113 mL 0.2259 mL 0.4518 mL 0.5648 mL
    * Note: If you are in the process of experiment, it's need to make the dilution ratios of the samples. The dilution data of the sheet for your reference. Normally, it's can get a better solubility within lower of Concentrations.
    Protocol
    Structure Identification:
    J Nat Prod. 2003 Sep;66(9):1191-6.
    Structures of new friedelane-type triterpenes and eudesmane-type sesquiterpene and aldose reductase inhibitors from Salacia chinensis.[Pubmed: 14510595 ]

    METHODS AND RESULTS:
    Three new friedelane-type triterpenes named salasones A (1), B (2), and C (3), a new norfriedelane-type triterpene, salaquinone A (4), and a new acylated eudesmane-type sesquiterpene, salasol A (5), were isolated from the 80% aqueous methanolic extract of the stems of Salacia chinensis collected in Thailand.
    CONCLUSIONS:
    Their stereostructures were elucidated on the basis of chemical and physicochemical evidence. In addition, six constituents, 3beta,22beta-dihydroxyolean-12-en-29-oic acid, tingenone, tingenine B, regeol A, Triptocalline A, and mangiferin, were found to show an inhibitory effect on rat lens aldose reductase.
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